English
















طباعة هذه الصفحة
الاسم: ا.د / ماريان الفونس محروس راغب
القسم: الكيمياء الصيدلية  
البريد الالكتروني: marianne.alphonse@pharma.cu.edu.eg  
الفاكس:
داخلي رقم.: 3183
الغرفة: C / 718
السيرة الذاتية: ملف السيرة الذاتية
Scholar: https://scholar.cu.edu.eg/?q=Marianne Alphonse Mahrouse
الموقع الالكتروني:
قائمة النشر - Publications 1) Determination of some antihypertensive agents as single component and in combination with hydrochlorothiazide. Bulletin of Faculty of Pharmacy, Cairo University, 2003, 41(3)/p.27-46
2) Simultaneous determination of indapamide and captopril in binary mixtures by derivative spectro-photometry and TLC densitometry. Bulletin of Faculty of Pharmacy, Cairo University, 2006, 44(2)/p. 63-76
3) Spectroscopic and chromatographic determination of fluvastatin sodium in presence of its acid degradate. International Journal of PharmTech Research, 2010, 2(1)/p. 875-898
4) Development and validation of a stability indicatimg HPLC method for the simultaneous determination of captopril and indapamide Analytical Chemistry: An Indian Journal, 2013, 12(6)/p. 222-232
5) Reversed-phase ion-pair HPLC and TLC-densitometric methods for the simultaneous determination of ciprofloxacin hydrochloride and metronidazole in tablets, Chromatographia, DOI:10.1007/s10337-010-1898-x, 2011, 73/p. 297-305
6) Validated spectrophotometric methods for the simultaneous determination of ciprofloxacin hydrochloride and metronidazole in tablets, Chemical and Pharmaceutical Bulletin, 2011, 59(12)/p. 1485-1493
7) Development and validation of a UV spectrophotometric method for the simultaneous determination of ciprofloxacin hydrochloride and metronidazole in binary mixture, Journal of Chemical and Pharmaceutical Research, 2012, 4(11)/
p. 4710-4715
8) A validated spectrofluorimetric method for the determination of nifuroxazide through coumarin formation using experimental design, Chemistry Central Journal, DOI:10.1186/1752-153X-7-90, 2013, 7:90/p. 1-12
9) Utility of experimental design in pre-column derivatization for the analysis of tobramycin by HPLC—fluorescence detection: Application to ophthalmic solution and human plasma, Analytical Chemistry Insights,
DOI: 10.4137/ACI.S11612, 2013, 8/p. 9–20
10) Simultaneous determination of amlodipine besylate and atorvastatin calcium in binary mixture by spectrofluorimetry and HPLC coupled with fluorescence detection, Analytical Chemistry Insights, DOI: 10.4137/ACI.S12921, 2013, 8/p. 107–115
11) Validated derivative spectrophotometric and chromatographic methods for the determination of doxazosin mesylate in presence of its degradation product and/or related impurity, International Journal of Pharmaceutical Analysis
(Recent Science Publications), 2013, 38(2)/p. 1146-1155
12) Validated difference spectrophotometric and stability indicating HPLC estimation of linezolid in tablets, International Journal of Pharmaceutical Analysis (Recent Science Publications), 2013, 38(2)/p. 1166-1173
13) Stability indicating spectrophotometric and TLC densitometric methods for the determination of gemifloxacin mesylate in tablet form, Analytical Chemistry: an Indian Journal, 2013, 12(5)/p. 165-176
14) Spectrophotometric determination of oxybutynin hydrochloride via charge - transfer complexation reaction International, Journal of Pharmaceutical and Chemical Sciences, 2013, 2(4)/p. 2024-2033
15) Spectrofluorimetric determination of gemifloxacin mesylate and linezolid in pharmaceutical formulation: Application of quinone-based fluorophores and enhanced native fluorescence, Acta Pharmaceutica, DOI:
10.2478/acph-2014-0005, 2014, 64/p. 15-28
16) Resolution of overlapped spectra for the determination of ternary mixture using different and modified spectrophotometric methods, Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy,
DOI:10.1016/j.saa.2016.04.003, 2016, 165/p. 127 - 137
17) Experimental design approach in HPLC method development: Application for the simultaneous determination of sacubitril and valsartan in presence of their impurities and investigation of degradation kinetics, Chromatographia, DOI: 10.1007/s10337-017-3425-9, 2018, 81/p.139-156
18) In vitro metabolism study of a novel P38 kinase inhibitor: in silico predictions, structure elucidation using MS/MS-I, Future Medicinal Chemistry, DOI: 10.4155/fmc-2017-0126, 2018, 10(2)/p. 201–220
19) Determination of four anti-epileptic drugs in plasma using ultra- performance liquid chromatography with mass detection technique, Biomedical Chromatography, DOI: 10.1002/bmc.4253, 2018, 32(8)/p. 1-9
20) A validated reversed-phase high-performance liquid chromatography method for simultaneous determination of five antiepileptic drugs used in the treatment of lennox-gastaut syndrome in their pharmaceutical dosage forms, Asian Journal of Pharmaceutical and Clinical Research, DOI:10.22159/ajpcr.2018.v11i5.24143, 2018, 11(5)/p. 167-173
21) Simultaneous HPLC determination of betamethasone esters-containing mixtures: Analysis of their topical preparations, Journal of Chromatographic Science, DOI: 10.1093/ chromsci/bmy047, 2018, 56(8)/p. 716 - 723
22) Smart spectrophotometric methods based on normalized spectra for simultaneous determination of alogliptin and metformin in their combined tablets, Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy, DOI:10.1016/j.saa.2018.07.004, 2018, 204/p. 743-747
23) Different resolution techniques for management of overlapped spectra: Application for the determination of novel co-formulated hypoglycemic drugs in their combined pharmaceutical dosage form, Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy, DOI:10.1016/j.saa.2018.06.072, 2018, 205/p. 235-242
24) Simultaneous ultraperformance liquid chromatography/tandem mass spectrometry determination of four antihypertensive drugs in human plasma using hydrophilic-lipophilic balanced reversed phase sorbents sample preparation protocol, Biomedical Chromatography, DOI:10.1002/bmc.4362, 2018, 32(12)/p. 1-10 (e4362)
25) A validated RP-HPLC method for the determination of rosuvastatin in presence of sacubitril/valsartan in rat plasma: Application to in vivo evaluation of OATP-mediated drug interaction potential between rosuvastatin and sacubitril/valsartan, Microchemical Journal, DOI:10.1016/j.microc.2018.07.021, 2018, 143/p. 31-38
26) A validated LC-MS/MS method for simultaneous determination of linagliptin and metformin in spiked human plasma coupled with solid phase extraction: Application to a pharmacokinetic study in healthy volunteers, Journal of Pharmaceutical and Biomedical Analysis, DOI: 10.1016/j.jpba.2018.09.052, 2019, 163/p. 153-161
27) Validated chromatographic methods for simultaneous estimation of cinnarizine in binary mixture with domperidone and paracetamol in tablets, Current Pharmaceutical Analysis, DOI:10.2174/1573412914666180307154921, 2019, 15(5)/p. 429-438
28) Validated chromatographic methods for the simultaneous estimation of etamsylate and mefenamic acid in presence of their main impurities, Current Pharmaceutical Analysis, DOI:10.2174/1573412914666180423142911, 2019, 15(6)/p. 624-631
29) Experimental design methodology for optimization and robustness determination in ion pair RP-HPLC method development: Application for the simultaneous determination of metformin hydrochloride, alogliptin benzoate and repaglinide in tablets, Microchemical journal, DOI:10.1016/j.microc.2019.03.038, 2019, 147/p. 691-706
30) A validated RP‐HPLC method for the evaluation of the influence of grapefruit juice on liver S9 activation of sacubitril, Biomedical Chromatography, DOI: 10.1002/bmc.4553, 2019, 33(8)/p. 1-8(e4553)
31) Novel spectrophotometric methods for the determination of Leflunomide and Diacerein in binary mixtures, Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy, DOI:10.1016/j.saa.2019.05.026, 2019, 220/p. 117-121
32) Determination of rufinamide in the presence of 1-[(2,6-difluorophenyl) methyl]-1H-1,2,3-triazole-4 carboxylic acid using RP-HPLC and derivative ratio methods as stability indicating assays to be applied on its dosage form, Journal of AOAC INTERNATIONAL, DOI:10.1093/jaoacint/qsaa020, 2020, 103(5)/p. 1215-1222
33) Simultaneous determination of cefixime and erdosteine in combined dosage form using validated spectrophotometric methods, Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy, DOI:
10.1016/j.saa.2020.118647, 2020, 241/p. 1386-1425
34) Validated LC–MS/MS method for the simultaneous determination of enalapril maleate, nitrendipine,
hydrochlorothiazide, and their major metabolites in human plasma, Biomedical chromatography, DOI: 10.1002/bmc.4955 2020, 34(12)/p. 1-11
(e4955)
35) Simultaneous determination of enalapril maleate and nitrendipine intablets using spectrophotometric methods manipulating ratio spectra, Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy, DOI:
10.1016/j.saa.2020.118894, 2021, 244/118894
36) Development and bio-analytical validation of chromatographic determination method of rufinamide in presence of its metabolite in human plasma, Journal of chromatographic science, DOI:10.1093/chromsci/bmaa142, 2021, bmaa142/p. 1-7
37) Synchronized determination of the novel heart failure combination therapy containing sacubitril calcium and valsartan by a validated spectrofluorimetric method, Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy, DOI:10.1016/j.saa.2021.119613, 2021, 253/119613
38) Smart spectrophotometric methods for the simultaneous determination of newly co-formulated hypoglycemic drugs in binary mixtures, Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy, DOI:
10.1016/j.saa.2021.119763, 2021, 257/119763
39) Synchronized determination of sacubitril and valsartan with some co-administered drugs in human plasma via UPLC-MS/MS method using solid phase extraction, Biomedical chromatography, DOI: 10.1002/bmc.5203, 2021, 35(10)/
p. 1-17(e5203)
40) Application of experimental design in HPLC method optimization and robustness for the simultaneous
determination of canagliflozin, empagliflozin, linagliptin, and metformin in tablet, Biomedical chromatography,
DOI: 10.1002/bmc.5155, 2021, 35(10)/p. 1-17 (e5155)
حقوق النسخ © كل الحقوق محفوظة كلية الصيدلة جامعة القاهرة | القصر العيني, القاهرة, جمهورية مصر العربية |رقم بريدي 11562
للاتصال بنا | تليفون: 23639307 - 23624917 - 2363245 - (00202) | فاكس: 23628246