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Name: Professor Dr. / Emad Basalious Bashir Basalious
Department: Pharmaceutics and Industrial Pharmacy  
Email: emad.basalious@pharma.cu.edu.eg  
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C.V.: C.V. File
Scholar: https://www.semanticscholar.org/author/E.-B.-Basalious/8593368?sort=pub-date
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Latest List of Publications Scientific Publications
International Scientific Publications (Scopus; 40)
1. Ramadan, A., Basalious, E., Abdallah, M., (2021), Industrial application of QbD and NIR chemometric models in quality improvement of Immediate release tablets,
Saudi Pharmaceutical Journal June 29(6): 516-526,
https://doi.org/10.1016/j.jsps.2021.04.012
2. Shaeer, O., Raheem, A. A., Elfeky, H., Seif, A., Abdel-Raheem, T. M., Elsegeiny, A., Soliman, M. S., Basalious, E. B., & Shaeer, K. (2021), Urethral instillation of chlorhexidine gel is an effective method of sterilisation, Arab journal of urology, 19(3), 419–422, https://doi.org/10.1080/2090598X.2021.1956832

3. Mohsen, K., Azzazy, H.M.E., Allam, N.K., Basalious, E.B., (2020), Intranasal lipid nanocapsules for systemic delivery of nimodipine into the brain: In vitro optimization and in vivo pharmacokinetic study, Material Science and Engineering: C 116, 111236,
https://doi.org/10.1016/j.msec.2020.111236
4. Farrah, A.Y., Al-Mahallawi, A.M., Basalious, E.B., Nesseem, D.I., (2020), Investigating the Potential of Phosphatidylcholine-Based Nano-Sized Carriers in Boosting the Oto-Topical Delivery of Caroverine: in vitro Characterization, Stability Assessment and ex vivo Transport Studies, Int J Nanomedicine Nov 13;15:8921-8931,
https://doi.org/10.2147/IJN.S259172
https://go.gale.com/ps/i.do?id=GALE%7CA646496982&sid=googleScholar&v=2.1&it=r&linkaccess=abs&issn=11782013&p=AONE&sw=w&userGroupName=anon%7Ea8413fe1
5. Yousry, C., Zikry, P.M., Basalious, E.B., El-Gazayerly, O.N., (2020), Self-nanoemulsifying System Optimization for Higher Terconazole Solubilization and Non-Irritant Ocular Administration, Adv Pharm Bull, 10(3), 389-398,
https://apb.tbzmed.ac.ir/Article/apb-28043
6. Abdel-Salam, F.S., Elkheshen, S.A., Mahmoud, A.A., Basalious, E.B., et. al. (2020), In-situ forming chitosan implant-loaded with raloxifene hydrochloride and bioactive glass nanoparticles for treatment of bone injuries: Formulation and biological evaluation in animal model, International Journal of Pharmaceutics, vol. 580, 119213,
https://doi.org/10.1016/j.ijpharm.2020.119213
7. Khattab, A., Mohamed, M., Basalious, E.B., (2020), Design of self-nanoemulsifying system to enhance absorption and bioavailability of poorly permeable Aliskiren hemi-fumarate, Journal of Drug Delivery Science and Technology 57; 101646,
https://doi.org/10.1016/j.jddst.2020.101646
8. Ibrahim, M.M., Basalious, E.B., El-Nabarawi, M.A., (2020), Consolidated bile-based vesicles/self-nanoemulsifying system (CBBVs/SNES) asa solution for limitations of oral delivery of vesicular dispersions: In-vitro optimization and elucidation of ex-vivo intestinal transport mechanisms, Journal of Drug Delivery Science and Technology, Vol: 56(A), Page: 101489,
https://doi.org/10.1016/j.jddst.2019.101489
9. Yousry, C., Zikry, P.M., Salem, H.M., Basalious, E.B., et al. (2020), Integrated nanovesicular/self-nanoemulsifying system (INV/SNES) for enhanced dual ocular drug delivery: statistical optimization, in vitro and in vivo evaluation, Drug Deliv Transl Res. 10, 801,
https://doi.org/10.1007/s13346-020-00716-5
10. ElShagea, H.N., ElKasabgy, N.A., Fahmy, R.H., Basalious, E.B., (2019), Freeze-Dried Self-Nanoemulsifying Self-Nanosuspension (SNESNS): a New Approach for the Preparation of a Highly Drug-Loaded Dosage Form, AAPS PharmSciTech 20(7):258,
https://doi.org/10.1208/s12249-019-1472-2
http://balis.bibalex.org/AR/OPAC/Home/SearchOPAC?keyword=%D8%B3%D9%86%D8%AC%D8%B1%D8%8C%20%D9%86%D8%B1%D9%85%D9%8A%D9%86.&filterId=_1&filterValue=_El-Shagea%2C%20Hala%20Nehad%20Hassan%20Ali%2C
11. Boseila, A.A., Abdel-Reheem, A.Y., Basalious, E.B., (2019), Design of bile-based vesicles (BBVs) for hepatocytes specific delivery of Daclatasvir: Comparison of ex-vivo transenterocytic transport, in-vitro protein adsorption resistance and HepG2 cellular uptake of charged and beta-sitosterol decorated vesicles, PloS one 14(7):e0219752,
https://doi.org/10.1371/journal.pone.0219752
12. Elkasabgy, N.A., Abdel-Salam, F.S., Mahmoud, A.A., Basalious, E.B., et al., (2019), Long lasting in-situ forming implant loaded with raloxifene HCl: An injectable delivery system for treatment of bone injuries, International journal of pharmaceutics 571:118703,
https://doi.org/10.1016/j.ijpharm.2019.118703
13. Sweed, N.M., Basalious, E.B., Nour, S.A., (2019), Combined site-specific release retardant mini-matrix tablets (C-SSRRMT) for extended oral delivery of dexketoprofen trometamol: in vitro evaluation and single versus multiple doses pharmacokinetic study in human volunteers, Drug development and industrial pharmacy 45(11):1777-87,
https://doi.org/10.1080/03639045.2019.1656737
14. Rezk, M.R., Basalious, E.B., & Badr, K.A., (2018), Novel determination of sofosbuvir and velpatasvir in human plasma by UPLC–MS/MS method: Application to a bioequivalence study,
Biomedical Chromatography, 32(11),
https://doi.org/10.1002/bmc.4347
15. Fouad, S.A., Shamma, R.N., Basalious, E.B., El-Nabarawi, M.M., & Tayel, S.A., (2018), Novel instantly-dispersible nanocarrier powder system (IDNPs) for intranasal delivery of dapoxetine hydrochloride: in-vitro optimization, ex-vivo permeation studies, and in-vivo evaluation, Drug Development and Industrial Pharmacy, 44(9), 1443–1450,
https://doi.org/10.1080/03639045.2018.1459675
16. Abo Elela, M.M., ElKasabgy, N.A., Basalious, E.B., (2017), Bio-shielding In Situ Forming Gels (BSIFG) Loaded With Lipospheres for Depot Injection of Quetiapine Fumarate: In Vitro and In Vivo Evaluation, AAPS PharmSciTech 18(8):2999-3010,
https://link.springer.com/content/pdf/10.1208/s12249-017-0789-y.pdf
17. Basalious, E.B., Abdallah, A.M., (2017), Phospholipid based self-nanoemulsifying self-nanosuspension (p-SNESNS) as a dual solubilization approach for development of formulation with diminished food effect: Fast/fed in vivo pharmacokinetics study in human,
European journal of pharmaceutical sciences: 109:244-52,
https://doi.org/10.1016/j.ejps.2017.08.017
18. El-Setouh, D.A., Basalious, E.B., Abdelmalak, N.S., (2017), Effect of Different Meltable Binders on the Disintegration and Dissolution Behavior of Zolmitriptan Oromucosal Fast Melt Tablets, Journal of Pharmacy and Nutrition sciences 7: 13-23,
https://doi.org/10.6000/1927-5951.2017.07.01.3
19. Hanna, L.A., Basalious, E.B., ON, EL., (2017), Respirable controlled release polymeric colloid (RCRPC) of bosentan for the management of pulmonary hypertension: in vitro aerosolization, histological examination and in vivo pulmonary absorption, Drug delivery 24(1):188,
https://doi.org/10.1080/10717544.2016.1239661
20. Rashed, H.M., Shamma, R.N., Basalious, E.B., (2016), Contribution of both olfactory and systemic pathways for brain targeting of nimodipine-loaded lipo-pluronics micelles: in vitro characterization and in vivo biodistribution study after intranasal and intravenous delivery, Drug delivery 24(1):181-7,
https://doi.org/10.1080/10717544.2016.1236848
21. Rezk, M.R., Bendas, E.R., Basalious, E.B., et al. (2016), Quantification of sofosbuvir and ledipasvir in human plasma by UPLC-MS/MS method: Application to fasting and fed bioequivalence studies, J. of chromatography B, Analytical technologies in the biomedical and life sciences 1028:63-70,
https://doi.org/10.1016/j.jchromb.2016.06.004
22. Rezk, M.R., Bendas, E.R., Basalious, E.B., et al. (2016), Development and validation of sensitive and rapid UPLC-MS/MS method for quantitative determination of daclatasvir in human plasma: Application to a bioequivalence study, J. of pharmaceutical and biomedical analysis 1028:61,
https://doi.org/10.1016/j.jpba.2016.05.016
23. Rezk, M.R., Basalious, E.B., Amin, M.E., (2016), Novel and sensitive UPLC-MS/MS method for quantification of sofosbuvir in human plasma: application to a bioequivalence study, Biomedical chromatography BMC 30(9):1354-62,
https://doi.org/10.1002/bmc.3690
24. Fouad, S.A., Shamma, R.N., Basalious, E.B., et al. (2016), Novel instantly-soluble transmucosal matrix (ISTM) using dual mechanism solubilizer for sublingual and nasal delivery of dapoxetine hydrochloride: In-vitro/in-vivo evaluation,
International journal of pharmaceutics 505(1-2):212-22,
https://doi.org/10.1016/j.ijpharm.2016.04.006
25. Bendas, E.R., Basalious, E.B., (2016), Rapidly disintegrating vagina retentive cream suppositories of progesterone: development, patient satisfaction and in vitro/in vivo studies,
Pharmaceutical development and technology 21(3):288-95,
https://doi.org/10.3109/10837450.2014.999784
26. Basalious, E.B., Shamma, R.N., (2015), Novel self-assembled nano-tubular mixed micelles of Pluronics P123, Pluronic F127 and phosphatidylcholine for oral delivery of nimodipine: In vitro characterization, ex vivo transport and in vivo pharmacokinetic studies,
International journal of pharmaceutics 493(1-2):347-56,
https://doi.org/10.1016/j.ijpharm.2015.07.075.
27. El-Setouhy, D.A., Basalious, E.B., et al. (2015), Bioenhanced sublingual tablet of drug with limited permeability using novel surfactant binder and microencapsulated polysorbate: In vitro/in vivo evaluation, European J. of Pharmaceutics and Biopharmaceutics 94, 386-392,
https://doi.org/10.1016/j.ejpb.2015.06.006.
28. Rezk, M.R., Basalious, E.B., Karim, I.A., (2015), Development of a sensitive UPLC-ESI-MS/MS method for quantification of sofosbuvir and its metabolite, GS-331007, in human plasma: Application to a bioequivalence study, J. of pharmaceutical and biomedical analysis 114:97-104,
https://doi.org/10.1016/j.jpba.2015.05.006.
29. El-Laithy, H.M., Basalious, E.B., et al. (2015), Novel self-nanoemulsifying self-nanosuspension (SNESNS) for enhancing oral bioavailability of diacerein: Simultaneous portal blood absorption and lymphatic delivery, International journal of pharmaceutics 490(1-2):146,
https://doi.org/10.1016/j.ijpharm.2015.05.039
30. Basalious, E.B., Abdullah, A., Ibrahim, M., (2014), Utility of Mannitol and Citric Acid for Enhancing the Solubilizing and Taste Masking Properties of β-Cyclodextrin: Development of Fast-Dissolving Tablets Containing Extremely Bitter Drug, J Pharm Innov., 9, 309-320, https://link.springer.com/article/10.1007%2Fs12247-014-9196-z
31. Fouad, S.A., Basalious, E.B., et al. (2013), Microemulsion and poloxamer microemulsion-based gel for sustained transdermal delivery of diclofenac epolamine using in-skin drug depot: in vitro/in vivo evaluation, International j. of pharmaceutics, 453(2): 569,
https://doi.org/10.1016/j.ijpharm.2015.07.058
32. Basalious, E.B., El-Sebaie, W., El-Gazayerly, O., (2013), Rapidly absorbed orodispersible tablet containing molecularly dispersed felodipine for management of hypertensive crisis: development, optimization and in vitro/in vivo studies,
Pharmaceutical development and technology, 18(2): 407-416,
https://doi.org/10.3109/10837450.2012.659258
33. Shamma, R.N., Basalious, E.B., Shoukri, R., (2012), Development of novel sustained release matrix pellets of betahistine dihydrochloride: effect of lipophilic surfactants and co-surfactants, Pharmaceutical development and technology, 17(5): 583-593,
https://doi.org/10.3109/10837450.2011.557730
34. Basalious, E.B., El-Sebaie, W., El-Gazayerly, O., (2011), Application of pharmaceutical QbD for enhancement of the solubility and dissolution of a class II BCS drug using polymeric surfactants and crystallization inhibitors: development of controlled-release tablets,
AAPS PharmSciTech, 12(3): 799-810,
https://doi.org/10.1208/s12249-011-9646-6
35. Shamma, R.N., Basalious, E.B., Shoukri, R.A., (2011), Development and optimization of a multiple-unit controlled release formulation of a freely water soluble drug for once-daily administration, International journal of pharmaceutics, 405(1-2): 102-112,
https://doi.org/10.1016/j.ijpharm.2010.12.003
https://agris.fao.org/agris-search/search.do?recordID=US201500124055
36. Aboelwafa, A.A., Basalious, E.B., (2010), Optimization and in vivo pharmacokinetic study of a novel controlled release venlafaxine hydrochloride three-layer tablet,
AAPS PharmSciTech, 11(3): 1026-1037,
https://doi.org/10.1208/s12249-010-9467-z
37. Basalious, E.B., Shawky, N., Badr-Eldin, S.M., (2010), SNEDDS containing bioenhancers for improvement of dissolution and oral absorption of lacidipine. I: development and optimization, International journal of pharmaceutics, 391(1-2): 203-211,
https://doi.org/10.1016/j.ijpharm.2010.03.008

38. Yehia, S.A., El-Gazayerly, O.N., Basalious, E.B., (2009), Fluconazole mucoadhesive buccal films: in vitro/in vivo performance, Current drug delivery, 6(1):17-27,
https://doi.org/10.2174/156720109787048195
39. Yehia, S.A., El-Gazayerly, O.N., Basalious, E.B., (2008), Design and in vitro/in vivo evaluation of novel mucoadhesive buccal discs of an antifungal drug: relationship between swelling, erosion, and drug release, AAPS PharmSciTech, 9(4):1207-1217, https://doi.org/10.1208/s12249-008-9166-1
40. El-Samaligy, M.S., Yahia, S.A., Basalious, E.B., (2004), Formulation and evaluation of diclofenac sodium buccoadhesive discs, International journal of pharmaceutics, 286(1-2): 27,
https://doi.org/10.1016/j.ijpharm.2004.07.033

International Scientific Publications (Non-Scopus; 3)
1. Sweed, N.M., Basalious, E.B., Nour, S.A., (2017), Sustained Release Multiple Unit Dosage Form for the Oral Day Delivery of Dexketoprofen Trometamol,
Open access J Pharm Res 1(3): 000114.
https://medwinpublishers.com/OAJPR/OAJPR16000114.pdf
2. Khowessah, O., Amin, M., Basalious, E.B., (2009), Development of ocular delivery systems containing aceclofenac nanoparticles. Part I: Optimization of nanoparticles formulations using full factorial design, J. Biomed. Sci., 31: 25-47.
3. El-Samaligy, M.S., Yahia, S.A., Basalious, E.B., (2001), Improved design for in-vitro measurement of adhesion parameters of bioadhesive pharmaceutical systems, Bull. Fac. Pharm.Cairo Univ., 39: 103-112.

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