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Name: Professor Dr. / Mohamed Refaat EL-Sayed El-Ghobashy
Department: Analytical Chemistry  
Email: mohamed.elghobashy@pharma.cu.edu.eg  
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C.V.: C.V. File
Scholar: https://scholar.cu.edu.eg/?q=mohamedrefaat
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Latest List of Publications 1. Y. S. El-Saharty, M. Refaat and S. Z. El-Khateeb"Stability-Indicating Spectrophotometric and Densitometric Methods for Determination of Aceclofenac."Journal of Drug Development and Industrial Pharmacy, (2002) Vol. 28 No. (5) page 571-582.
2. Y. S. El-Saharty, M. Refaat and S. Z. El-Khateeb"Simultaneous determination of Diclofenac Sodium and Diflunisal." Bull. Fac. Pharm. Cairo Univ., (2002) Vol. 40 No. 3 page 47-64.
3. Y. S. El-Saharty, F.H. Metwaly, M. Refaat and S. Z. El-Khateeb"Application of a new membrane selective electrodes for the determination of drotaverine hydrochloride in tablets and plasma."Journal of Pharmaceutical and Biomedical Analysis, (2006) Vol. 41 page 720–724.
4. Y. S. El-Saharty, F.H. Metwaly, M. Refaat and S. Z. El-Khateeb "Simultaneous determination of Hyoscine butylbromide and Ketoprofen in pharmaceutical preparations by spectrophotometric and HPLC methods." Journal of AOAC INTERNATIONAL, (2007) Vol. 90 No. 1 page 102-112.
5. 5- F.H. Metwaly, Y. S. El-Saharty, M. Refaat and S. Z. El-Khateeb "Application of derivative, derivative ratio, multivariate spectral analysis and TLC-densitometric methods for determination of a ternary mixture containing drotaverine hydrochloride, caffeine and paracetamol." Journal of AOAC INTERNATIONAL, (2007) Vol. 90, No. 2 page 391-404.
6. Y. S. El-Saharty, F.H. Metwaly, M. Refaat and S. Z. El-Khateeb “Development of membrane electrodes for the selective determination of hyoscine butylbromide." Talanta, (2007) Vol. 72 No. 2 page 675–681.
7. F.H. Metwaly, Y. S. El-Saharty, M. Refaat and S. Z. El-Khateeb " Spectrophotometric Methods and Application of a New Membrane Selective Electrodes for the Simultaneous Determination of Mebeverine Hydrochloride and Sulpiride." Bull. Fac. Pharm. Cairo Univ., (2007) Vol. 45 No. 3 page 13-29.
8. Nesrin Khamis, Hala El-Sayed Zaazaa, Maha Hegazy, Mohamed Refaat “Stability indicating TLC densitometric and chemometric methods for the simultaneous determination of etofibrate in its alkaline induced degradation products." Az. J. Pharm. Sci., (2007) Vol. 36 page 23-37.
9. Mohamed R. El-Ghobashy, Nisreen F. Abo-Talib. "Application of derivative ratio and TLC-densitometric methods for determination of a ternary mixture containing metronidazole, diloxanide furoate and mebeverine hydrochloride." Bull. Fac. Pharm. Cairo Univ., (2008) Vol. 46 No. 1 page 75-86.
10. M. R. El-Ghobashy, A. M. Yehia, and A. A. Mostafa " Stability indicating methods for the determination of pioglitazone hydrochloride in presence of its degradation product." Bull. Fac. Pharm. Cairo Univ., (2008) Vol. 46 No. 2 page 25-34.
11. M. R. El-Ghobashy, A. M. Yehia, and A. A. Mostafa “Application of Membrane-Selective Electrodes for the Determination of Pioglitazone Hydrochloride in the Presence of Its Acid Degradant or Metformin Hydrochloride in Tablets and Plasma.” Analytical letters, (2009) Vol. 42 No. 1 page 123-140.
12. Samah Sayed Abbas, Hala El-Sayed Zaazaa, Mohamed Refaat El-Ghobashy, Yasmin Mohammed Fayez*, Soheir Abdel Fattah “Stability Indicating Methods For Determination Of Ziprasidone Hydrochloride.” Analytical Chemistry: An Indian J., (2009) Vol. 8 No. 2.
13. Maha A. Hegazy, Mohamed R. El-Ghobashy, Ali M. Yehia and Azza A. Mostafa “Simultaneous determination of metformin hydrochloride and pioglitazone hydrochloride in binary mixture and in their ternary mixture with pioglitazone acid degradate using spectrophotometric and chemometric methods”. Drug Testing and Analysis J., (2009) Vol. 1 No. 7 page 339-349.
14. Nisreen F.Abo-Talib, Mohamed R.El-Ghobashy “Simultaneous Determination Of Pipenzolate Bromide And Phenobarbitone In Pharmaceutical Preparations By HPLC Method.” Analytical Chemistry: An Indian J., (2009) Vol. 8 No. 4 page 511-515.
15. Samah Sayed Abbas, Hala El-Sayed Zaazaa, Mohamed Refaat El-Ghobashy, Yasmin Mohammed Fayez, Soheir Abdel Fattah “Stability indicating methods for determination of nafronyl oxalate”. Analytical Chemistry: An Indian J., (2009) Vol. 8 No. 4 page 613-620.
16. Mohamed R. El-Ghobashy, Hala E. Zaazaa “Membrane electrodes for determination of two antihypertensive drugs in pharmaceutical formulations of either single or binary mixtures and in biological fluids”. Drug Discoveries & Therapeutics, (2010) Vol. 4 No. (3) page 217-222.
17. Nouruddin W. Ali, Mohamed R. El-Ghobashy, Mohammed Gamal, Mohammed Abdelkawy “TLC-Spectrodensitometric And Microemulsion RP-HPLC Chromatographic Methods For Determination Of Orphenadrine And Paracetamol”. Analytical Chemistry: An Indian J., (2010) Vol. 9 No. 2 page 298-304.
18. Mohamed R. El-Ghobashy, Nisreen F. Abo-Talib. “Spectrophotometric methods for the simultaneous determination of binary mixture of metronidazole and diloxanide furoate without prior separation”. Journal of Advanced Research, (2010) Vol. 1 No. 4 page 323-329.
19. Nouruddin W. Ali, Mohamed R. El-Ghobashy, Mohammed Gamal, Mohammed Abdelkawy “SPECTROPHOTOMETRIC AND SPECTROFLUORIMETRIC METHODS FOR DETERMINATION OF RACECADOTRIL”. Pak. J. Pharm. Sci., (2011) Vol. 24, No.1 page 19-23.
20. Samah Sayed Abbas, Hala El-Sayed Zaazaa, Mohamed Refaat El-Ghobashy, Yasmin Mohammed Fayez, Soheir Abdel Fattah “Stability indicating methods for determination of Naftidrofuryl Oxalate”. Analytical Chemistry: An Indian J., (2012) Vol. 11 No. 11, 12 page 329-334.
21. Samah S. Abbas, Mohamed R. Elghobashy, Rafeek F. Shokry, Lories I. Bebawy “Stability indicating HPLC and spectrophotometric methods for the determination of bupropion hydrochloride in the presence of its alkaline degradates and related impurity” Bull. Fac. Pharm. Cairo Univ., (2012) Vol. 50 No. 1 page 49-59.
22. Samah Sayed Abbas, Hala El-Sayed Zaazaa, Mohamed Refaat El-Ghobashy, Yasmin Mohammed Fayez, Soheir Abdel Fattah “Application of Membrane-Selective Electrodes for the Determination of Naftidrofuryl Oxalate in the Presence of Its Alkaline Degradant in Tablets and Plasma” Portugaliae Electrochimica Acta., (2012) Vol. 30 No. 3 page 177-188.
23. Ghada AbdElHamid, Mohamed Refaat ElGhobashy, Eman Saad ElZanfaly, Sawsan Mohamed Amer and Sonia Zaki ElKhateeb “Ion Selective Membrane Electrodes for Stability-Indicating Determination of Amisulpride” Anal. Bioanal. Electrochem., (2012) Vol. 4, No. 6 page 579 - 592.
24. Mohamed Refaat Elghobashy, Osama Mohamed Badran, Maissa Yacoub Salem and Khadiga Mohamed Kelani “Application of Membrane Selective Electrodes for the Determination of Azelastine Hydrochloride in the Presence of its Alkaline Degradant in Eye drops and Plasma” Anal. Bioanal. Electrochem., (2013) Vol. 5, No. 3 page 325 - 340.
25. Mohamed Refaat Elghobashy, Osama Mohamed Badran, Maissa Yacoub Salem and Khadiga Mohamed Kelani “Simultaneous UV- spectrophotometric techniques for determination of chlorpheniramine maleate and naphazoline hydrochloride in eye drops”. Analytical Chemistry: An Indian J., (2013) Vol. 13 No. 2, page 69-76.
26. Mohamed R. Elghobashy, Lories I. Bebawy, Samah S. Abbas, Rafeek F. Shokry “Stability-Indicating HPLC and RP-TLC Determination of Cefpirome Sulfate with Kinetic Study” Chromatographia, (2013) Vol. 76, No.17-18, page 1141-1151.
27. Mohamed R. Elghobashy and Mamdouh R. Rezk “Comparative Study of Different Ionophores in Ion Selective Electrodes for Stability indicating Determination of Moxifloxacin” Anal. Bioanal. Electrochem., (2014) Vol 6, No. 4, page 461-474
28. Mohamed Refaat Elghobashy, Osama Mohamed Badran, Maissa Yacoub Salem and Khadiga Mohamed Kelani “Stability indicating spectrophotometric and chromatographic methods for the determination of azelastine hydrochloride in presence of its alkaline degradant” Analytical Chemistry: An Indian J., (2014) Vol. 14 No. 4.
29. Maha M. Abdelrahman, Ibrahim A. Naguib, Mohamed R. El Ghobashy, Nesma A. Ali “Quantitative determination of Zopiclone and its impurity by four different Spectrophotometric methods” Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscop (SAA), (2015) Vol. 137, page 617-624.
30. Mohamed R. Elghobashy, Amr M. Mahmoud, Mamdouh R. Rezk, and Mohamed K. Abd El-Rahman “Strategy for Fabrication of Stable Tramadol Solid-Contact Ion-Selective Potentiometric Sensor Based on Polyaniline Nanoparticles” J. Electrochem. Soc., (2015) Vol. 162, No. 1, page H1-H5.
31. Mohamed K. Abd El-Rahman, Mamdouh R. Rezk, Amr M. Mahmoud and Mohamed R. Elghobashy “Design of a Stable Solid-Contact Ion-Selective Electrode based on Polyaniline Nanoparticles as Ion-to-Electron Transducer for Application in Process Analytical Technology as a Real-Time Analyzer” Sensors and Actuators B: Chemical, (2015) Vol. 208, No. 3, pages 14–21.
32. Nesma A. Ali, Maha M. Abdelrahman, Ibrahim A. Naguib and Mohamed R. Elghobashy “Development of membrane electrode for the selective determination of bromazepam in tablets and plasma ” Anal. Bioanal. Electrochem., (2015) Vol. 7, No. 2, page 242-253.
33. Samah S. Abbas, Mohamed R. Elghobashy, Lories I. Bebawy and Rafeek F. Shokry “Stability-indicating chromatographic determination of hydroquinone in combination with tretinoin and fluocinolone acetonide in pharmaceutical formulation with photodegradation kinetic study” RSC Advances, (2015) Vol. 5, No. 54, page 43178-43194.
34. Ibrahim A. Naguib, Maha M. Abdelrahman, Mohamed R. El Ghobashy and Nesma A. Ali “HPTLC Method for Quantitative Determination of Zopiclone and Its Impurity” Journal of Chromatographic Science, (2015) Vol. 53, No. 8, page 1395-1399.
35. Amr M. Mahmoud, Mohamed K. Abd El-Rahman, Mohamed R. Elghobashy and Mamdouh R. Rezk “Carbon nanotubes versus polyaniline nanoparticles; which transducer offers more opportunities designing a stable solid contact ion-selective electrode” Journal of Electroanalytical Chemistry, (2015) Vol. 755, page 122-126.
36. Ahmed S. Saad, Nisreen F. Abo-Talib and Mohamed R. El-Ghobashy “Novel ratio difference at coabsorptive point spectrophotometric method for determination of components with wide variation in their absorptivities” Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscop (SAA), (2016) Vol. 152, page 480-484.
37. Mohamed R. Elghobashy, Lories I. Bebawy, Rafeek F. Shokry and Samah S. Abbas “Successive ratio subtraction coupled with constant multiplication spectrophotometric method for determination of hydroquinone in complex mixture with its degradation products, tretinoin and methyl paraben” Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscop (SAA), (2016) Vol. 157, page 116-123.
38. Lories I. Bebawy, Mohamed R. Elghobashy, Samah S. Abbas, and Rafeek F. Shokry “Chromatographic Determination of Aminoacridine Hydrochloride, Lidocaine Hydrochloride and Lidocaine Toxic Impurity in Oral Gel” Journal of Chromatographic Science, under press.
39. Yasmine M. Fayez, Mohamed R. Elghobashy, Zeinab M. Goda, Mostafa A. Shehata “Comparative study on four spectrophotometric methods manipulating ratio spectra for simultaneous determination of binary mixture of diflucortolone valerate and isoconazole nitrate” Bull. Fac. Pharm. Cairo Univ., under press.
40. Mohamed R. Elghobashy, Yasmine M. Fayez, Zeinab M. Goda, Mostafa A. Shehata “HPLC and TLC chromatographic methods for simultaneous determination of binary mixture of isoconazole nitrate and diflucortolone valerate” Bull. Fac. Pharm. Cairo Univ., under press.

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