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Name: Associate Professor Dr. / Heba AbdElRasheed AbdElKhalek Allam
Department: Pharmaceutical Chemistry  
Email: heba.abdelkhalek@pharma.cu.edu.eg  
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C.V.: C.V. File
Scholar: https://scholar.cu.edu.eg/?q=hebaallam80
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Latest List of Publications 1- ‘Dual-tail arylsulfone-based benzenesulfonamides differently match the hydrophobic and hydrophilic halves of human carbonic anhydrases active sites: Selective inhibitors for the tumor-associated hCA IX isoform’ H.S. Ibrahima, H.A. Allam, W.R. Mahmoud, A. Bonardicd, A. Nocentinic, P. Gratteri, E. S. Ibrahim, H.A. Abdel-Aziz and C.T. Supuranc, European Journal of Medicinal Chemistry (2018) Vol. 152, 1-9
2- ‘Synthesis and biological evaluation of some novel thiobenzimidazole
derivatives as anti-renal cancer agents through inhibition of c-MET kinase’
H. S. Ibrahima, M. E. Albakri, W. R. Mahmoud, H. A. Allam, A. M. Reda, H. A. Abdel-Aziz. Bioorganic Chemistry (2019) Vol. 85, 337-348.
3- ‘Application of hydrazino and hydrazido linkers to connect benzenesulfonamides with hydrophilic/phobic tails for targeting the middle region of human carbonic anhydrases active site: Selective inhibitors of hCA IX’ H. A. Allam, S. H. Fahim, M. F.Abo-Ashour, A. Nocentini, M. E. Elbakry, M. A. Abdelrahman, W. M. Eldehna, H. S. Ibrahim, C. T. Supuran. European Journal of Medicinal Chemistry (2019) Vol. 179, 547-556.
4- ‘Design, synthesis and biological evaluation of some new 1,3,4-thiadiazine-thiourea derivatives as potential antitumor agents against non-small cell lung cancer cells’ F. A. F. Ragab, S. A. Abdel-Aziz, M. Kamel, A. M. A. Ouf, H. A. Allam. Bioorganic Chemistry (2019) Vol. 93, 103323
5- ‘Synthesis and vasodilator activity of some pyridazin-3(2H)-one based compounds’ H. A. Allam1, A. A. Kamel, M. El-Daly, R. F. George. Future Medicinal Chemistry (2020) Vol. 12(1), 37–50
6- ‘Design and Synthesis of some new 2,4,6-trisubstituted quinazoline EGFR inhibitors as targeted anticancer agents’ H. A. Allam, E. E. Aly, A. K. B. A. W. Farouk, A. M. El Kerdawy, E. Rashwan, S. E. S. Abbass. Bioorganic Chemistry (2020) Vol. 98, 103726
7- ‘Design and synthesis of novel coumarin derivatives as potential acetylcholinesterase inhibitors for Alzheimer's disease’ K. M. Amin, D. E. Abdel Rahman, H. A. Allam, H. H. El-Zoheiry Bioorganic Chemistry (2021) Vol. 110, 1047928.
8- ‘Nanomolar potency of imidazo[2,1-b]thiazole analogs as indoleamine 2,3-dioxygenase inhibitors’ Menna A. Ewida1 Heba A. Ewida, Mahmoud S. Ahmed Heba A. Allam, Ramzia I. ElBagary, Riham F. George, Hanan H. Georgey, Hussein I. El‐Subbagh, Archiv der Pharmazie (2021) 2100202
doi.org/10.1002/ardp.202100202
9- ‘3-Methyl-imidazo[2,1-b]thiazole derivatives as a new class of antifolates: Synthesis, in vitro/in vivo bio-evaluation and molecular modeling simulations’ Menna A. Ewida , Heba A. Ewida, Mahmoud S. Ahmed, Heba A. Allam , Ramzia I. ElBagary, Riham F. George, Hanan H. Georgey, Hussein I. El-Subbagh, Bioorganic Chemistry (2021) Vol. 115, 1052025 doi.org/10.1016/j.bioorg.2021.105205
10- ‘Design and synthesis of novel pyridopyrimidine derivatives with anchoring non-coplanar aromatic extensions of EGFR inhibitory activity’ Amal A.M. Eissa, Kholoud F.M. Aljamal, Hany S. Ibrahim, Heba A. Allam. Bioorganic Chemistry (2021) Vol. 116, 105318 doi.org/10.1016/j.bioorg.2021.105318
11- ‘Natural Inspired Ligustrazine-based SLC-0111 Analogues as Novel Carbonic Anhydrase Inhibitors’ D. M.Elimam, W. M. Eldehna, R. Salem, A. Bonardi, A. Nocentini, S. T.Al-Rashood, M. M. Elaasser, P. Gratteri, C. T.Supuran, H. A. Allam. European Journal of Medicinal Chemistry (2021) (2022) Vol. 228, 114008. doi.org/10.1016/j.ejmech.2021.114008
12- ‘Design, synthesis, cytotoxic and enzyme inhibitory activities of 1,3,4-oxadiazole and 1,3,4-thiadiazine hybrids against non-small cell lung cancer’ A. M. A. Ouf, H. A. Allam, M. Kamel, F. A. Ragab, S. A. Abdel-Aziz. Results in Chemistry (2022) Vol. 4, 100373

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