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Name: Professor Dr. / Khaled Omar Ahmed Mohamed
Department: Pharmaceutical Organic Chemistry  
Email: khaled.mohamed@pharma.cu.edu.eg  
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Latest List of Publications Publications (h-index 10)
24. Khaled O. Mohamed Zeinab Mahmoud , Hadeer S. Sayed, Lamia W. Mohamed, Development of new donepezil analogs: synthesis, biological screening and in silico study rational. Medicinal Chemistry Research, 2022, 8 (31), 1-17.

23. Peter A. Halim, Rasha A. Hassan, Khaled O. Mohamed, Soha O. Hassanin, Mona G. Khalil, Amr M. Abdou & Eman O. Osman , Synthesis and biological evaluation of halogenated phenoxychalcones and their corresponding pyrazolines as cytotoxic agents in human breast cancer. Journal of inhibition & medicinal chemistry, 2022, 37(1), 189-201.
22. Ahdab N. Khayyat, Khaled O. Mohamed, Azizah M. Malebari and Afaf El-Malah. “Design, Synthesis, and Antipoliferative Activities of Novel Substituted Imidazole-Thione Linked Benzotriazole Derivatives”. Molecules 2021, 26, 5983, 1-17.
21. Marian W.Aziz, Aliaa M.Kamal , Khaled O.Mohamed, Adel A.Elgendy.“Design, synthesis and assessment of new series of quinazolinone derivatives as EGFR inhibitors along with their cytotoxic evaluation against MCF7 and A549 cancer cell lines. Bioorganic & medicinal chem, letters. 2021, 41,127987, 1-11.
20. Abdelhameid, Mohammed K., Islam Zaki, Manal R. Mohammed, and Khaled O. Mohamed. "Design, synthesis, and cytotoxic screening of novel azole derivatives on hepatocellular carcinoma (HepG2 Cells)." Bioorganic chemistry 101 (2020): 103995.
19. Shaaban, Mohamed A., Yaseen AMM Elshaier, Ali H. Hammad, Nahla A. Farag, Haredy Hassan Haredy, Ahmed A. AbdEl-Ghany, and Khaled O. Mohamed. "Design and synthesis of pyrazolo [3,4-d] pyrimidinone derivatives: Discovery of selective phosphodiesterase-5 inhibitors." Bioorganic & Medicinal Chemistry Letters 30, no. 16 (2020): 127337.
18. Shabaan, Mohamed A., Aliaa M. Kamal, Samar I. Faggal, Ayman E. Elsahar, and Khaled O. Mohamed. "Synthesis and biological evaluation of pyrazolone analogues as potential anti‐inflammatory agents targeting cyclooxygenases and 5‐lipoxygenase." Archiv der Pharmazie 353, no. 4 (2020): 1900308.
17. Nissan, Yassin M., Khaled O. Mohamed, Wafaa A. Ahmed, Dina M. Ibrahim, Marwa M. Sharaky, Tamer M. Sakr, Mohamed A. Motaleb, Ahmed Maher, and Reem K. Arafa. "New benzenesulfonamide scaffold-based cytotoxic agents: Design, synthesis, cell viability, apoptotic activity and radioactive tracing studies." Bioorganic chemistry 96 (2020): 103577.
16. Mohamed, Khaled O., Islam Zaki, Ibrahim M. El-Deen, and Mohammed K. Abdelhameid. "A new class of diamide scaffold: Design, synthesis and biological evaluation as potent antimitotic agents, tubulin polymerization inhibition and apoptosis inducing activity studies." Bioorganic chemistry 84 (2019): 399-409.
15. Shaaban, Mohamed A., Khalid O. Mohamed, Mohamed E. Hegazi, Montaser Sh A. Shaykoon, and Yaseen AMM Elshaier. "Synthesis of Some Pyrimidine and Fused Pyrimidine Derivatives with Antimicrobial and Anticancer Activities." Der Pharma Chemica, 2018, 10(7): 180-200.
14. Zaki, Islam, Mohammed K. Abdelhameid, Ibrahim M. El-Deen, Abdel Hady A. Abdel Wahab, Abeer M. Ashmawy, and Khaled O. Mohamed. "Design, synthesis and screening of 1, 2, 4-triazinone derivatives as potential antitumor agents with apoptosis inducing activity on MCF-7 breast cancer cell line." European journal of medicinal chemistry 156 (2018): 563-579.
13. Mohamed, Khaled O., Yassin M. Nissan, Afaf A. El-Malah, Wafaa A. Ahmed, Dina M. Ibrahim, Tamer M. Sakr, and Mohamed A. Motaleb. "Design, synthesis and biological evaluation of some novel sulfonamide derivatives as apoptosis inducers." European journal of medicinal chemistry 135 (2017): 424-433.
12. Moneer, Ashraf A., Khaled O.Mohammed, and Hala B. El‐Nassan. "Synthesis of Novel Substituted Thiourea and Benzimidazole Derivatives Containing a Pyrazolone Ring as Anti‐Inflammatory Agents." Chemical biology & drug design 87, no. 5 (2016): 784-793.
11. El-Ansary, Afaf KE, Neama A. Mohamed, Khaled O. Mohamed, Hend MW Abd-Elfattah, and Mai El-Manawaty. "A Simple and Convenient Synthesis of Novel Thiopyrimidine Derivatives as Anticancer Agents." Research Journal of Pharmaceutical, Biological and Chemical Sciences, 6(4), 1745-1752 (2015).‎
10. Mohamed, Khaled O. "SYNTHESIS OF 2-THIAZOLYLIDENE DERIVATIVES WITH CYTOTOXIC ACTIVITY." Journal of science 5(2015): 781-786.
9. Ashraf M. Hamouda and Khaled O. Mohamed. “Synthesis and Antimicrobial Evaluation of Some New Dihydropyrimidine Derivatives. Der Pharma Chemica 7(2015): 116-125.
8. Mohammed, Khaled O., and Yassin M. Nissan. "Synthesis, molecular docking, and biological evaluation of some novel hydrazones and pyrazole derivatives as anti‐inflammatory agents." Chemical biology & drug design 84, no. 4 (2014): 473-488.
7. Khalil, Nadia Abdalla, Eman Mohamed Ahmed, Khaled O. Mohamed, Yassin Mohammed Nissan, and Sawsan Abo-Bakr Zaitone. "Synthesis and biological evaluation of new pyrazolone–pyridazine conjugates as anti-inflammatory and analgesic agents." Bioorganic & medicinal chemistry 22, no. 7 (2014): 2080-2089.
6. Rahman, DE Abdel and Khaled O. Mohamed. "Synthesis of novel 1, 3, 4-thiadiazole analogues with expected anticancer activity." Der Pharma Chemica 6, no. 1 (2014): 323-335.
5. Khalil, Nadia Abdalla, Eman Mohamed Ahmed, Khaled O. Mohamed, and Sawsan Abo-Bakr Zaitone. "Synthesis of new nicotinic acid derivatives and their evaluation as analgesic and anti-inflammatory agents." Chemical and Pharmaceutical Bulletin 61, no. 9 (2013): 933-940.
4. Abouzid, Khaled AM, Nadia A. Khalil, Eman M. Ahmed, and Khaled O. Mohamed. "3-[(6-Arylamino)pyridazinylamino] benzoic acids: design, synthesis and in vitro evaluation of anticancer activity." Archives of pharmacal research 36, no. 1 (2013): 41-50.
3. Abd El Hameid, Mohammed Kamal, Hala Bakr El-Nassan, and Khaled Omar Ahmed. "Synthesis, antimicrobial and cytotoxic activity of novel 4-phenoxy and 4-(substitutedamino) pyrazolo [3, 4-d] pyrimidine derivatives." Journal of Organic Chemistry: An Indian Journal, 36, no. 9 (2013): 350-362.
2. M.A. Shaaban, L. N. Soliman, S. M. A. Roshdy and K. O. Mohamed. “Synthesis of some isoxazolo(1,4)diazepines, pyrazolo(1,5)Benzoxazepines and pyrazolo(1,5)benzodiazepines related To CNS acting drugs.” Bull. Fac. Pharm. Cairo University 47 no. 3 (2009).
1. F. A. El Telbany, S. M. A. Roshdy, A. K. El-Ansary and K.O. Mohamed. “Synthesis and antimicrobial activity of some substituted isoxazole derivatives”. Bull. Fac. Pharm. Cairo University 40 no. 2 (2002).

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