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Name: Associate Professor Dr. / Essam Eldin Abdelfattah Osman
Department: Pharmaceutical Chemistry  
C.V.: C.V. File
Latest List of Publications 1. Abd El-Mageed, Menna MA, Amal AM Eissa, Awatef El-Said Farag, and Essam Eldin A. Osman. "Design and synthesis of novel furan, furo [2, 3-d] pyrimidine and furo [3, 2-e][1, 2, 4] triazolo [1, 5-c] pyrimidine derivatives as potential VEGFR-2 inhibitors." Bioorganic Chemistry 116 (2021): 105336.
2. Essam Eldin A. Osman, Alnawaz A Rehemtulla, and Nouri Neamati. "Why All the Fury over Furin?." Journal of Medicinal Chemistry (2021).
3. Ahmed A. Elbatrawy, Seung Jae Hyeon, Nan Yue, Essam Eldin A. Osman, Seung Hyeo Choi, Sungsu Lim, Yun Kyung Kim, Hoon Ryu, Mengchao Cui, and Ghilsoo Nam. “Turn-On” Quinoline-Based Fluorescent Probe for Selective Imaging of Tau Aggregates in Alzheimer’s Disease: Rational Design, Synthesis, and Molecular Docking.”, ACS Sensors 6 (6), (2021), 2281-2289.
4. Essam Eldin A. Osman, Noura S. Hanafy, Riham F. George, and Samir M. El-Moghazy. "Design and synthesis of some barbituric and 1, 3-dimethylbarbituric acid derivatives: A non-classical scaffold for potential PARP1 inhibitors." Bioorganic Chemistry 104 (2020): 104198.
5. Essam Eldin A. Osman, Peter L. Toogood, and Nouri Neamati. "COVID-19: Living through Another Pandemic." ACS Infectious Diseases (2020).
6. Abd-Allah, Walaa Hamada, Essam Eldin A. Osman, Mostafa Abd-El-Mohsen Anwar, Hanan Naeim Attia, and Samir M. El Moghazy. "Design, Synthesis and docking studies of novel benzopyrone derivatives as anticonvulsants." Bioorganic Chemistry (2020): 103738.
7. Youssif, Bahaa GM, Ashraf M. Mohamed, Essam Eldin A. Osman, Ola F. Abou-Ghadir, Dina H. Elnaggar, Mostafa H. Abdelrahman, Laurent Treamblu, and Hesham AM Gomaa. "5-Chlorobenzofuran-2-carboxamides: From allosteric CB1 modulators to potential apoptotic antitumor agents." European Journal of Medicinal Chemistry 177 (2019): 1-11.
8. Hisham, Mohamed, Bahaa GM Youssif, Essam Eldin A. Osman, Alaa M. Hayallah, and Mohamed Abdel-Aziz. "Synthesis and biological evaluation of novel xanthine derivatives as potential antitumor apoptotic agents." European Journal of Medicinal Chemistry 176 (2019): 117-128.
9. Moussa, Shaimaa A., Essam Eldin A. Osman, Nahed M. Eid, Sahar M. Abou-Seri, and Samir M. El Moghazy. "Design and Synthesis of Novel 5-(4-Chlorophenyl) Furan Derivatives with Inhibitory Activity on Tubulin Polymerization". Future Medicinal Chemistry 10, no. 16 (2018): 1907-1925.
10. Nowar, Raghad M., Essam Eldin A. Osman, Sahar M. Abou-Seri, Samir M. El Moghazy, and Dalal A. Abou El Ella. "Design, Synthesis and Biological Evaluation of Some Novel Quinazolinone Derivatives as Potent Apoptotic Inducers". Future Medicinal Chemistry 10, no. 10 (2018): 1191-1205.
11. Essam Eldin A. Osman, "Analytical Investigation of Different Mathematical Approaches Utilizing Manipulation of Ratio Spectra". Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy 188 (2018): 469-477.
12. Ahmed, Riham I., Essam Eldin A. Osman, Fadi M. Awadallah, and Samir M. El-Moghazy. "Design, Synthesis and Molecular Docking of Novel Diarylcyclohexenone and Diarylindazole Derivatives as Tubulin Polymerization Inhibitors". Journal of Enzyme Inhibition and Medicinal Chemistry 32, no. 1 (2017): 176-188.
13. El-Moghazy, Samir M., Riham F. George, Essam Eldin A. Osman, Ahmed A. Elbatrawy, Miroslava Kissova, Ambra Colombo, Emmanuele Crespan, and Giovanni Maga. "Novel Pyrazolo [3, 4-d] pyrimidines as Dual Src-Abl Inhibitors Active against Mutant Form of Abl and the Leukemia K-562 Cell Line". European Journal of Medicinal Chemistry 123 (2016): 1-13.
14. Moussa, Bahia A., Ramzia I. El-Bagary, and Essam Eldin A. Osman. "Determination of Letrozole in Pharmaceutical Preparation and Human Plasma Based on Fluorometric Detection". Analytical Chemistry Letters 3, no. 2 (2013): 139-146.
16. Moussa, Bahia A., Ramzia I. El-Bagary, and Essam Eldin A. Osman. "Optimized Spectrophotometric Methods for the Determination of Raloxifene Hydrochloride". International Research Journal of Pure and Applied Chemistry 3, no. 3 (2013): 220.
17. Moussa, Bahia A., Ramzia I. El-Bagary, and Essam Eldin A. Osman. “Spectrophotometric and Chromatographic Methods for the Estimation of Raloxifene Hydrochloride in Bulk and Pharmaceutical Formulations”. American Chemical Science Journal, 3(4) (2013): 378-386.

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