Tile: Practical Approaches to Metabolomic Data Analysis in Medicine and Herbal Drug Research
Instructor: Prof. Dr. Mohamed Ali Farag (FOPCU)
Affiliation:
- Professor, Faculty of Pharmacy, Cairo, Egypt
- Alexander von Humboldt fellow, Germany
- TWAS fellow from Africa
- UNESCO Prize Laureate
- Journal of Advanced Research Managing Editor
- Efood Editor in Chief
Biography:
Specializing in metabolomics, natural products chemistry, and plant biochemistry, Mohamed A. Farag completed his PhD at Texas Tech University, USA, in 2003. In 2005, after spending time as a postdoctoral fellow at The Samuel Noble Foundation, USA, and the James Graham Brown Cancer Center, USA, he became assistant professor in 2005 at the Faculty of Pharmacy, Cairo University, Egypt.
Since 2009, Dr Farag has been working as a part-time visiting professor at the Technical University of Munich, Germany, to participate in teaching plant metabolomics and chemometrics modelling for master students, and in 2009–2010 he held the Alexander von Humboldt fellowship at the Leibniz Institute for Plant Biochemistry, Germany. Dr Farag now works full time as a professor at the Pharmacognosy Department within the Faculty of Pharmacy, Cairo University where his research work focuses primarily on applying innovative biochemical technologies (metabolomics) to help answer complex biological questions in medicine, herbal drugs analysis, and agriculture.
Dr. Farag has been recognized with several awards, including UNESCO Award in life sciences 2023, Egypt Higher State Merit Award (2023), Abd el Hameed Shoman award (2016), Egypt Higher State Incentive Award (2012), Cairo University Incentive Award (2009), TWAS award in science diplomacy (2014), and the Mass
Spectroscopy Performance Award, TTU, USA (2004), for his highly cited publications with close to 16,000 citations and an H index of 62.
Dr. Farag was selected as a top researcher in the field of plant biology in Africa by the American society of plant biology, USA.
Dr. Farag is a current TWAS fellow in Agriculture from Egypt.
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Workshop Description:
The ability to sequence whole plant and human genomes has taught us that our knowledge with respect to gene function is rather limited. Functional genomics analyses include investigations at the level of gene expression (transcriptomics), protein translation (proteomics) and more recently the metabolite network (metabolomics). Metabolomics is the study of global metabolite profiles in a system (cell, tissue, or organism) under a given set of conditions. This seminar provides an overview of metabolomics and discusses its complementary role within system biology. It highlights how metabolome analyses are being conducted using different spectroscopic techniques, and how the highly complex data generated are analyzed using bioinformatics tools. Specific examples will then be presented to illustrate how metabolomics can lead to valuable information relative to natural products biosynthesis, herbal medicines quality control analysis, and lastly disease diagnosis.
Covered content:
The workshop will provide introduction to omics technologies, the latest developments and spectroscopic strategies in the field of GCMS and LCMS based metabolomics, applications in the field of herbal medicine and food analysis. Training on multivariate data analysis from MS datasets shall be provided using Metaboanalyst program.