كلية الصيدلة جامعة القاهرة

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ا.د / مينا ابراهيم تادرس عياد

الصيدلانيات و الصيدلة الصناعية

mina.tadros@pharma.cu.edu.eg

ملف السيرة الذاتية

https://scholar.google.com.eg/citations?hl=en&user=uNZcX1UAAAAJ&view_op=list_wor

Latest List of Publications

 Foda NH, El-laithy HM, Tadros MI. Optimization of biodegradable sponges as controlled release drug matrices: I. effect of moisture level on chitosan sponge mechanical properties. Drug Dev Ind Pharm. 2004; 30(4): 369-379.
 Foda NH, El-laithy HM, Tadros MI. Implantable biodegradable sponges: effect of inter-polymer complex formation of chitosan with gelatin on the release behavior of tramadol hydrochloride. Drug Dev Ind Pharm. 2007; 33(1): 7-17.
 Elbary AA, El-laithy HM, Tadros MI. Promising ternary dry powder inhaler formulations of cromolyn Sodium: formulation and in vitro – in vivo evaluation. Arch Pharm Res. 2007; 30 (6): 785 - 792.
 Bendas ER, Tadros MI. Enhanced transdermal delivery of salbutamol sulfate via ethosomes. AAPS PharmSciTech. 2007; 8 (4): E1-E8.
 Abdelbary GA, Tadros MI. Design and in vitro/in vivo evaluation of novel nicorandil extended release matrix tablets based on hydrophilic interpolymer complexes and a hydrophobic waxy polymer. Eur J Pharm Biopharm. 2008; 69 (3): 1018-1028.
 Abd-Elbary A, El-laithy HM, Tadros MI. Sucrose stearate-based proniosome-derived niosomes for the nebulisable delivery of cromolyn sodium. Int J Pharm. 2008; 357 (1- 2): 189-198.
 Tadros MI. Controlled-release effervescent floating matrix tablets of ciprofloxacin hydrochloride: Development, optimization and in vitro-in vivo evaluation in healthy human volunteers. Eur J Pharm Biopharm. 2010; 74(2): 332-339.
 Ghorab DM, Amin MM, Khowessah OM, Tadros MI. Colon-targeted celecoxib-loaded Eudragit® S100-coated poly-ϵ-caprolactone microparticles: preparation, characterization and in vivo evaluation in rats. Drug Del. 2011; 18(7): 523–535.
 Abd-Elbary A, Tadros MI, Alaa-Eldin AA. Development and in vitro/in vivo evaluation of etodolac controlled porosity osmotic pump tablets. AAPS PharmSciTech. 2011; 12(2): 485-495.
 ElMeshad AN, Tadros MI. Transdermal delivery of an anti-cancer drug via w/o emulsions based on alkyl polyglycosides and lecithin: design, characterization and in vivo evaluation of the possible irritation potential in rats. AAPS PharmSciTech. 2011; 12(1): 1-9.
 Tayel SA, El-Nabarawi MA, Tadros MI, Abd-Elsalam WH. Promising ion-sensitive in situ ocular nanoemulsion gels of terbinafine hydrochloride: Design, in vitro characterization and in vivo estimation of the ocular irritation and drug pharmacokinetics in the aqueous humor of rabbits. Int J Pharm. 2013; 443(1-2): 293 – 305.
 Abdelbary GA, Tadros MI. Brain targeting of olanzapine via intranasal delivery of core - shell difunctional block copolymer mixed nanomicellar carriers: in-vitro characterization, ex-vivo estimation of nasal toxicity and in-vivo biodistribution studies. Int J Pharm. 2013; 452(1-2): 300-10.
 Tayel SA, El-Nabarawi MA, Tadros MI, Abd-Elsalam WH. Positively charged polymeric nanoparticle reservoirs of Terbinafine hydrochloride: Preclinical implications for controlled drug delivery in the aqueous humor of rabbits. AAPS PharmSciTech. 2013;14(2): 782-93.
 Abd-Elbary A, Tadros MI, Alaa-Eldin AA. Sucrose stearate-enriched lipid matrix tablets of etodolac: modulation of drug release, diffusional modeling and structure elucidation studies. AAPS PharmSciTech. 2013; 14(2): 656-68.
 Tadros MI, Fahmy RH. Controlled-release triple anti-inflammatory therapy based on novel gastroretentive sponges: Characterization and magnetic resonance imaging in healthy volunteers. Int J Pharm. 2014; 472(1-2): 27-39.
 Tayel SA, El-Nabarawi MA, Tadros MI, Abd-Elsalam WH. Duodenum-triggered delivery of pravastatin sodium via enteric surface-coated nanovesicular spanlastic dispersions: development, characterization and pharmacokinetic assessments. Int J Pharm. 2015; 483(1-2): 77-88.
 Yehia SA, El-Ridi MS, Tadros MI, El-Sherif NG. Enhancement of the oral bioavailability of fexofenadine hydrochloride via Cremophor EL-based liquisolid tablets. Adv Pharm Bull 2015; 5(4): 569-581.
 Yehia SA, El-Ridi MS, Tadros MI, El-Sherif NG. Phenylalanine-free taste-masked orodispersible tablets of fexofenadine hydrochloride: Development, in vitro evaluation and in vivo estimation of the drug pharmacokinetics in healthy human volunteers. Pharm Dev Tech. 2015; 20(5): 528–539.
 Abd-Elbary, A., Makky, A.M.A., Tadros, M.I., Alaa-Eldin, A.A. Development and in vitro evaluation of mucoadhesive bilayer buccal tablets of carvedilol. Int J Pharm Pharm Sci. 2015; 7(9): 172-176.
 Tadros MI, Al-mahallawi AM. Long-circulating lipoprotein-mimic nanoparticles for smart intravenous delivery of a practically insoluble antineoplastic drug: Development, preliminary safety evaluations and preclinical pharmacokinetic studies. Int J Pharm. 2015; 493(1-2): 439–450.
 Abd-Elbary A, Makky AM, Tadros MI, Alaa-Eldin AA. Laminated sponges as challenging solid hydrophilic matrices for the buccal delivery of carvedilol microemulsion systems: Development and proof of concept via mucoadhesion and pharmacokinetic assessments in healthy human volunteers. Eur J Pharm Sci. 2016; 82: 31-44.
 Tayel SA, El-Nabarawi MA, Tadros MI, Abd-Elsalam WH. Duodenum-triggered delivery of pravastatin sodium: II. Design, appraisal and pharmacokinetic assessments of enteric surface-decorated nanocubosomal dispersions. Drug Deliv. 2016; 23(9): 3266–3278.
 El-Gendy M, El-Assal M, Tadros MI, El-Gazayerly O. Olmesartan medoxomil-loaded mixed micelles: Preparation, characterization and in-vitro evaluation. Fut J Pharm Sci. 2017;3: 90-94.
 El-Assal M, El-Gendy M, El-Assal M, Tadros MI, El-Gazayerly O. Olmesartan medoxomil-loaded self-nanoemulsifying drug delivery systems: Design, in-vitro characterization, and pharmacokinetic assessments in rabbits via LC-MS/MS. Int J Drug Del Technol. 2017; 7(3): 210-219.
 Aboumanei MH, Abdelbary AA, Ibrahim IT, Tadros MI, El-Kolaly MT. Design and development of microemulsion systems of a new antineoplaston A10 analog for enhanced intravenous antitumor activity: In vitro characterization, molecular docking, 125I-radiolabeling and in vivo biodistribution studies. Int J Pharm. 2018; 545(1-2): 240-253.
 Aboumanei MH, Abdelbary AA, Ibrahim IT, Tadros MI, El-Kolaly MT. Improved Targeting and Tumor Retention of a Newly Synthesized Antineoplaston A10 Derivative by Intratumoral Administration: Molecular Docking, Technetium 99m Radiolabeling, and In Vivo Biodistribution Studies. Cancer Biother Radiopharm. 2018; 33(6): 221-232.
 Ammar HO, Mohamed MI, Tadros MI, Fouly AA. Transdermal delivery of Ondansetron hydrochloride via bilosomal systems: In-vitro, ex-vivo and in-vivo characterization studies. AAPS PharmSciTech. 2018; 19(5), 2276-2287.
 Tawfik MA, Tadros MI, Mohamed MI. Lipomers (lipid-polymer hybrid particles) of vardenafil hydrochloride: a promising dual platform for modifying the drug release rate and enhancing its oral bioavailability. AAPS PharmSciTech. 2018; 19(8), 3650-3660.
 Tawfik MA, Tadros MI, Mohamed MI. Polyamidoamine (PAMAM) dendrimers as potential release modulators and oral bioavailability enhancers of Vardenafil hydrochloride. Pharm Dev Tech. 2019; 24(3), 293-302.
 Ghoneim AM, Tadros MI, Alaa-Eldin AA. Spray-dried silica xerogel nanoparticles as a promising gastroretentive carrier system for the management of chemotherapy-induced nausea and vomiting. Int J Nanomedicine. 2019; 14, 9619–9630.
 Elsegaie D, Teaima M, Tadros MI, Louis D, El-Nabarawi MA. Formulation and in-vitro characterization of self-nanoemulsifying drug delivery system (SNEDDS) for enhanced solubility of candesartan cilexetil. Research J Pharm and Tech. 2019; 12(6): 2628-2636.
 Ammar HO, Tadros MI, Salama NM, Ghoneim AM. Therapeutic strategies for erectile dysfunction with emphasis on recent approaches in nanomedicine. IEEE T Nanobiosci. 2020; 19(1): 11-24.
 Elkady OA, Tadros MI, El-laithy HM. QbD approach for novel crosslinker-free ionotropic gelation of risedronate sodium-chitosan nebulizable microspheres: Optimization and characterization. AAPS PharmSciTech. 2020; 21(1): article 14, 1-18.
 Abd El-Aziz MF, Ismail S, Tadros MI, Elnabarawi MA. Alfuzosin hydrochloride-loaded low-density gastroretentive sponges: development, in vitro characterization and gastroretentive monitoring in healthy volunteers via MRI. Pharm Dev Technol. 2020; 25(5): 566-578.
 El-Maghawry E, Tadros MI, Elkheshen SA, Abd-Elbary A. Eudragit® S100 coated PLGA nanoparticles for colon-targeting of etoricoxib: Optimization and pharmacokinetic assessments in healthy human volunteers. Int J Nanomedicine. 2020; 15: 3965–3980.
 EL-Ghareb WI, Swidan MM, Ibrahim IT, Abd El-bary A, Tadros MI, Sakr TM. 99mTc-Doxorubicin-loaded gallic acid-gold nanoparticles (99mTc-DOX-loaded GA-Au NPs) as a multifunctional theranostic agent. Int J Pharm. 2020; 586: 119514.
 Ammar HO, Tadros MI, Salama NM, Ghoneim AM. Ethosome-derived invasomes as a potential transdermal delivery system for vardenafil hydrochloride: Development, optimization and application of physiologically based pharmacokinetic modeling in adults and geriatrics. Int J Nanomedicine. 2020; 15, 5671-5685.
 Ammar HO, Mohamed MI, Tadros MI, Fouly AA. High frequency ultrasound mediated transdermal delivery of ondansetron hydrochloride employing bilosomal gel systems: Ex-vivo and in-vivo characterization studies. J Pharm Investig. 2020; 50(6), 613-624.
 Tawfik, M.A., Tadros, M.I., Mohamed, M.I., El-Helaly, S.N. Low-frequency versus high-frequency ultrasound-mediated transdermal delivery of agomelatine-loaded invasomes: Development, optimization and in-vivo pharmacokinetic assessment. Int J Nanomedicine. 2020; 15, 8893-8910.
 Rana M Gebreel RM, Edris NA, Elmofty HM, Tadros MI, El-Nabarawi MA, Hassan DH. Development and characterization of PLGA nanoparticle-laden hydrogels for sustained ocular delivery of norfloxacin in the treatment of Pseudomonas keratitis: An experimental study. Drug Des Devel Ther 2021; 15, 399–418
 Mabrouk A.A., Tadros, M.I., El-Refaie WM. Improving the efficacy of cyclooxegenase-2 inhibitors in the oral cancer management: Insights into the implementation of nanotechnology and mucoadhesion. J Drug Deliv Sci Technol. 2021; 61, 102240.
 Elkady OA, Tadros MI, El-laithy HM. Nebulization of risedronate sodium microspheres for potential attenuation of pulmonary emphysema: A promising new insight of alveolar macrophage apoptosis. AAPS PharmSciTech. 2021; 22 (5): article 202, 1-11.
 Abd El-Aziz MF, Ismail S, Tadros MI, Elnabarawi MA. Low density alfuzosin hydrochloride floating tablets: in vitro characterization and in vivo gastroretentive MRI tracking in healthy volunteers. Pharm. Sci. Asia. 2021; 48(5), 433-450.
 Tawfik, M.A., Tadros, M.I., Mohamed, M.I., El-Helaly, S.N. Low-frequency sonophoresis as an active approach to potentiate the transdermal delivery of agomelatine-loaded novasomes: design, optimization, and pharmacokinetic profiling in rabbits. AAPS PharmSciTech. 2021; 22 (8): article 261, 1-15.
 Ammar, H.O., Tadros, M.I., Salama, N.M., Ghoneim, A.M. Development of vardenafil hydrochloride-loaded silica nanoparticles with enhanced transdermal delivery. Journal of Research in Pharmacy, 2022, 26(3), 451–459.

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