ا.د / نيفين شوقى عبد الملاك ابراهيم
الصيدلانيات و الصيدلة الصناعية
nevine.abdelmalak@pharma.cu.edu.eg
Latest List of Publications
S. A. Nour, M.M. Nafadi and N.S. Abdel Malak. Physical Characteristics and Availability of Ketorolac Tromethamine from Different Controlled Release Systems Egypt.J.Pharm.Sci 2005; 46, 21-42.
S. A. Nour, M.M. Nafadi and N.S. Abdel Malak Preparation and Evaluation of Ketorolac Tromethamine beads Using alginate Az.J.Pharm.Sci. 2005; 32, 33-47.
S. A. Nour, M.M. Nafadi and N.S. Abdel Malak pharmaceutical and pharmacological Evaluation of Ketorolac Tromethamine Beads Using Gelrite as Drug Carrier. Egypt Pharm.J. 2006; 5, 1-16.
Doaa Ahmed El-Setouhy and Nevine S. Abd El-Malak .Formulation of a Novel Tianeptine Sodium Orodispersible Film AAPS PharmSciTech. 2010; 10 ,18-25.
Rania A. Sanad, Nevine S. AbdelMalak, Tahany S. elBayoomy, and Alia A. Badawi Formulation of a Novel Oxybenzone-Loaded Nanostructured Lipid Carriers (NLCs) AAPS PharmSciTech. 2010 ;4, 1684-94.
Emad B. Basalious, Nevine Shawky, Shaimaa M. Badr-Eldin SNEDDS containing bioenhancers for improvement of dissolution and oral absorption of lacidipine. I: Development and optimization International Journal of Pharmaceutics 2010; 391, 203–11.
Rania A. Sanad, Nevine S. AbdelMalak, Tahany S. elBayoomy, and Alia A. Badawi Preparation and characterization of oxybenzone loaded solid lipid nanoparticles (SLNs) with enhanced safety and sunscreening efficacy: SPF and UVA-PF Drug Discoveries& Therapeutics 2010; 4, 472-83.
Sara M. Soliman, Nevine S. Abdel Malak, Omaima N. El-Gazayerly, Abdel Aziz Abdel Rehim Formulation of microemulsion gel systems for transdermal delivery of celecoxib: In vitro permeation, anti-inflammatory activity and skin irritation tests Drug Discoveries & Therapeutics 2010; 4 , 459-71.
Sara M. Soliman, Nevine S. Abdel Malak, Omaima N. El-Gazayerly, Abdel Aziz Abdel Rehim. Preparation of Celecoxib Solid Dispersions for Dermal Application: In Vitro characterization and Skin Irritation Test.J. Drug Delivery Science and technology2011; 21, 509-16.
Nevine S. Abdel Malak and , Shahira F el Menshawi. New topical fluconazole microsponge loaded hydrogel: Preparation and characterization . International Journal of Pharmacy and Pharmaceutical Sciences 2012;14, 460-8.
N. S. Abdel Malak. Formulation of coated polymer reinforced gellan gum beads of tizanidine HCl using fractional factorial design. International Journal of Pharmacy and Pharmaceutical Sciences,2012 ; 5, 368-79.
S. A. Nour, N. S. AbdelMalak, and M. J. Naguib. Bumadizone calcium dihydrate microspheres compressed tablets for colon targeting: formulation, optimization and in vivo evaluation. Drug Delivery 2015 ;22,286-97.
Rahman, S. A., N. S. AbdelMalak, A. Badawi, T. Elbayoumy, N. Sabry, and A. E. Ramly. Formulation of tretinoin-loaded topical proniosomes for treatment of acne: in-vitro characterization, skin irritation test and comparative clinical study. Drug Delivery 2015; 22, 731-9.
H. K. Ibrahim, N. S. Abdel Malak, and S. A. A. Halim. Formulation of Convenient, Easily Scalable, and Efficient Granisetron HCl Intranasal Droppable Gels. Mol Pharm 2015; 12, 2019-25.
D.A.El-Setouhy, E. B. Basalious, and N. S. AbdelMalak. Bioenhanced sublingual tablet of drug with limited permeability using novel surfactant binder and microencapsulated polysorbate: In vitro/in vivo evaluation. European Journal of Pharmaceutics and Biopharmaceutics 2015; 94, 386-92
D. A. El-Setouhy, N. S .Abdelmalak, S. E Anis and D. Louis. Leflunomide Biodegradable microspheres intended for intra-articular administration: development, anti -Inflammatory activity and histopathological Studies. International Journal of Pharmaceutics, 2015 ;30, 664-70.
Rahman, S. A., N. S. Abdelmalak, A. Badawi, T. Elbayoumy, N. Sabry, and A. E. Ramly. Tretinoin-loaded liposomal formulations: from lab to comparative clinical study in acne patients. Drug Delivery, 2016 ; 23,1184-93
. S. M. Soliman, N. S. Abdelmalak, O. N. El-Gazayerly, and N. Abdelaziz Novel non-ionic surfactant proniosomes for transdermal delivery of lacidipine: optimization using 23 factorial design and in vivo evaluation in rabbits. Drug Delivery, 2016; 23, 1608-22.
S. A. Nour, N S. Abdelmalak, M J. Naguib, H M. Rashed and A. B. Ibrahim. Intranasal brain-targeted clonazepam polymeric micelles for immediate control of status epilepticus: in vitro optimization, ex vivo determination of cytotoxicity, in vivo biodistribution and pharmacodynamics studies. Drug Delivery, 2016; 23,3681-95.
S.A. Nour, N. S. Abdelmalak, M.J. Naguib. Novel chewable colon targeted tablets of bumadizone calcium for treatment of ulcerative colitis: Formulation and optimization. Journal of Drug Delivery Science and Technology, 2016 ; 35 , 172-83.
D. A. El-Setouhy, E. B. Basalious and N. S. Abdelmalak. Effect of different meltable binders on the disintegration and dissolution behavior of zolmitriptan oromucosal fast melt tablets. Journal of Pharmacy and Nutrition Sciences, 2017 ; 7, 13-23.
N. M. El-Sayyad, A. Badawi, M.E. Abdullah, N. S. Abdelmalak. Dissolution enhancement of leflunomide incorporating self emulsifying drug delivery systems and liquisolid concepts. Bulletin Faculty of Pharmacy Cairo University, 2017; 55,53-62
S.A. Nour, N. S. Abdelmalak, M.J. Naguib. Transferosomes for trans-nasal brain delivery of clonazepam: preparation, optimization, ex-vivo cytotoxicity and pharmacodynamic study Open Access Journal of Pharmaceutical Research,2017;1,1-17.
Michael M. Farag, Nevine S. Abd El Malak, Soad A. Yehia Controlled buccal patches of Zaleplon using melt granulation technique: An approach to overcome early morning awakening Journal of Drug Delivery Science and Technology, 2018 ; 43, 439-445.
Michael M. Farag, Nevine S. Abd El Malak, Soad A. Yehia .Zaleplon loaded bi-layered chronopatch: A novel buccal chronodelivery approach to overcome circadian rhythm related sleep disorder International Journal of Pharmaceutics, 2018 ;542, 117-124.
Reham W. Hammad, Rania A. Sanad, Nevine S. Abdelmalak, Randa L. Aziz. Intranasal surface-modified mosapride citrate-loaded nanostructured lipid carriers (MOS-SMNLCs) for treatment of reflux diseases: in vitro optimization, pharmacodynamics, and pharmacokinetic studies AAPS PharmSciTech. 2018;19, 3791-3808.
HananM El Laithy , Alia A Badawy, Nevine S Abdelmalak , Nihal el Sayyad. Cubosomes as oral drug delivery systems: A promising approach for enhancing the release of clopidogrel bisulphate in the intestine. Chemical and Pharmaceutical Bulletin 2018; 66, 1165-1173.
Hanan M El Laithy , Alia A Badawy, Nevine S Abdelmalak , Nihal el Sayyad. Stabilizing excipients for engineered clopidogrel bisulfate procubosome
derived in situ cubosomes for enhanced intestinal dissolution: Stability and
bioavailability considerations European Journal of Pharmaceutical Sciences2019 ; 136, 104954
Sandy N. Aziz, Alia A. Badawy, Demiana I. Nessem, Nevine S. Abd El Malak
Promising nanoparticulate system for topical delivery of diphenhydramine
hydrochloride: In-vitro and in-vivo evaluation Journal of Drug Delivery Science and Technology, 2020 ; 55, 101454
Mina Louis, Alia A. Badawy, Demiana I. Nessem, Nevine S. Abd El Malak Drotaverine hydrochloride gastroretentive floating mini-tablets: Formulation, in-vitro and in-vivo evaluation Journal of Drug Delivery Science and Technology, 2020 ;57, 101733
Reham Hammad,Rania Sanad , Nevine S. Abd El Malak . Faisal Torrad, Randa Latif New intranasal cross-linked mosapride xyloglucan pluronics micelles (MOS-XPMs) for reflux esophagitis disease: In-vitro optimization and improved therapeutic efficacy journal of advanced research , 2020;23,83-94
Michael M. Farag, Nevine S. Abd El Malak, Soad A. Yehia , M Abdalla Sonocomplexation as an effective tool to enhance the antitumorigenic effect of Metformin: Preparation, in vitro characterization, molecular dynamic simulation & MiaPaCa-2 cell line hypoxia evaluation Journal of Drug Delivery Science and Technology, 2020, 59, 101968
Rehab Abdelmonem, Sammar F. Elhabal, Nevine S. Abdelmalak Mohamed A. El-Nabarawi and Mahmoud H. Teaima Formulation and Characterization of Acetazolamide/Carvedilol Niosomal Gel for Glaucoma Treatment: In Vitro, and In Vivo Study Pharmaceutics 2021, 13, 221
Michael M Farag Nevine S Abd El Malak Soad A Yehia Mohammed A Ahmed Hyaluronic Acid Conjugated Metformin-Phospholipid Sonocomplex: A Biphasic Complexation Approach to Correct Hypoxic Tumour Microenvironment
International Journal of Nanomedicine 2021
Michael M Farag , Mina M Louis, Alia A Badawy , Demiana I Nessem , Nevine S Abd Elmalak
Drotaverine Hydrochloride Superporous Hydrogel Hybrid System: a gastroretentive approach for sustained drug delivery and enhanced viscoelasticity. AAPS pharmscitech 2022