ا.د / صافيناز السيد عباس إبراهيم
الكيمياء الصيدلية
safinaz.abbas@pharma.cu.edu.eg
J-110
Latest List of Publications
1- Design and synthesis of some new 2,4,6- trisubstituted quinazoline EGFR inhibitors as anticancer agents
H.A.Allam, E.E.Aly, A.K.B.A.W.Farouk, A.M.Elkerdawy, E. Rashwan, S.E- S.Abbas
Bioorganic Chemistry(2020) vol 98, 103726.
2- HER-2 kinase Targeted Breast Cancer Therapy: Design, Synthesisand in Vitro and in Vivo Evaluation of Novel Lapatinib Congeners as Selective and potent HER-2 Inhibitors with Favorable Metabolic Stability
ELwaie,TamerA., Abbas, S.E., Aly Enayat I. , George, Riham F., Ali, Hamdy, Kraiouchkine,Nikolai, Abdelwahed, khaldoun S., Fandy, Tamer E., Elsayed, Khalid A., Abd Elmageed, Zakaria Y. , Ali Hamed I.
Journal of Medicinal Chemistry (2020),vol 63, Issue24, 15906-15945.
3- Design and synthesis of some new 6- bromo-2-
( pyridin-3- yl)-4- substituted quinazolines as multityrosine kinase inhibitors
A.K.B.A.W.Farouk, H.A. Allam, E.Rashwan, R.F. George, S.E- S. Abbas
Bioorganic Chemistry (2022), vol 128, 106099.
4-Some 2-(4- bromophenoxymethyl)-6- iodo-3- substituted quinazolin-4-(3H)ones: Synthesis, cytotoxic activity, EGFRinhibition and molecular docking
Abbas, SafinazE- S, Abdelgawad, Nagwa M., George, Riham F., AbuElyazid, Mohamed G, Zaatar, Marwa A., ElAshrey, Mohamed K.
Journal of Molecular structure, (2022),
vol12695, article number 133851.
5- Design and synthesis of some new benzoylthioureidophenyl derivatives targeting carbonic anhydrase enzymes
M.A.A. Najm, W.R. Mahmoud, Azza T. Taher, S. E- S. Abbas, F. M. Awadallah, H.A.Allam, D. Vullo(20, C.T. Supuran
Journal of Enzyme Inhibition and Medicinal Chemistry (2022) vol 37:1, 2702-2709.
6- Design and synthesis of some new benzoylthioureido benzenesulfonamide derivatives and their analogues as carbonic anhydrase inhibitor
K.H. Oudah, W.R. Mahmoud, F.M.Awadallah, A.T. Taher,, S.E-S. Abbas, H.A.Allam, D. Vullo, C. T. Supuran
Journal of Enzyme Inhibition and Medicinal Chemistry(2023) vol 38:1, 12-23