Lecturer Dr. / Mohamed Kandeel Mohamed El-Ashrey
Pharmaceutical Chemistry
mohamed.elashrey@pharma.cu.edu.eg
Latest List of Publications
Abbas, S.E., Abdel-Gawad, N.M., George, R.F., Elyazid, M.G.A., Zaater, M.A. and El-Ashrey, M.K., 2022. Some 2-(4-bromophenoxymethyl)-6-iodo-3-substituted quinazolin-4 (3H) ones: Synthesis, cytotoxic activity, EGFR inhibition and molecular docking. Journal of Molecular Structure, p.133851.
El-Sayed, N.N., Almaneai, N.M., Ben Bacha, A., El-Ashrey, M.K., Al-Zaben, M.I. and Almarhoon, Z.M., 2022. Biological Evaluation, Molecular Docking Analyses, and ADME Profiling of Certain New Quinazolinones as Anti-colorectal Agents. ACS Omega.
Fouad, M.A., Al-Khalil Bek, N., El-Zaher, A., Sammany, M. and El-Ashrey, M., 2022. Quantitative Structure Retention/Activity Relationship Study of some Dialkoxybenzamide Phosphodiesterase-4B Inhibitors. Egyptian Journal of Chemistry, 65(9), pp.1-4.
El-Sayed, N.N., Almaneai, N.M., Ben Bacha, A., El-Ashrey, M.K., Al-Zaben, M.I. and Almarhoon, Z.M., 2022. Biological Evaluation, Molecular Docking Analyses, and ADME Profiling of Certain New Quinazolinones as Anti-colorectal Agents. ACS Omega.
El-Ashrey, M.K., Bakr, R.O., Fayed, M.A., Refaey, R.H. and Nissan, Y.M., 2022. Pharmacophore based virtual screening for natural product database revealed possible inhibitors for SARS-COV-2 main protease. Virology, 570, pp.18-28.
El-Deen, E.M.M., Anwar, M.M., Abd El-Gwaad, A.A., Karam, E.A., El-Ashrey, M.K. and Kassab, R.R., 2022. Design and synthesis of some novel pyridothienopyrimidine derivatives and their biological evaluation as antimicrobial and anticancer agents targeting EGFR enzyme. Arabian Journal of Chemistry, 15(4), p.103751.
Mohi El-Deen, E.M., Anwar, M.M., El-Gwaad, A.A.A., Karam, E.A., El-Ashrey, M.K. and Kassab, R.R., 2022. Novel Pyridothienopyrimidine Derivatives: Design, Synthesis and Biological Evaluation as Antimicrobial and Anticancer Agents. Molecules, 27(3), p.803.
• El-Hussieny, M., Abd-El-Maksoud, M.A., Soliman, F.M., Fouad, M.A. and El-Ashrey, M.K., 2023. Dual-target ligand discovery for Alzheimer’s disease: triphenylphosphoranylidene derivatives as inhibitors of acetylcholinesterase and β-amyloid aggregation. Journal of Enzyme Inhibition and Medicinal Chemistry, 38(1), p.2166040.
• Ibrahim, K.A., El-Ashrey, M.K., Kashef, M.T. and Helmy, O.M., 2023. Alanine racemase a promising Helicobacter pylori drug target inhibited by propanoic acid. Microbes and Infection, p.105167.
• Ghamry, H.I., Belal, A., El-Ashrey, M.K., Tawfik, H.O., Alsantali, R.I., Obaidullah, A.J., El-Mansi, A.A. and Abdelrahman, D., 2023. Evaluating the ability of some natural phenolic acids to target the main protease and AAK1 in SARS COV-2. Scientific Reports, 13(1), p.7357.
• Al-Warhi, T., Almahli, H., Maklad, R.M., Elsayed, Z.M., El Hassab, M.A., Alotaibi, O.J., Aljaeed, N., Ayyad, R.R., Ghabour, H.A., Eldehna, W.M. and El-Ashrey, M.K., 2023. 1-Benzyl-5-bromo-3-hydrazonoindolin-2-ones as Novel Anticancer Agents: Synthesis, Biological Evaluation and Molecular Modeling Insights. Molecules, 28(7), p.3203.
• Mohamed, A.R., Mostafa, A., El Hassab, M.A., Hedeab, G.M., Mahmoud, S.H., George, R.F., Georgey, H.H., Gawad, N.M.A. and El-Ashrey, M.K., 2023. Insights into targeting SARS-CoV-2: design, synthesis, in silico studies and antiviral evaluation of new dimethylxanthine derivatives. RSC Medicinal Chemistry.