|Latest List of Publications
||1- Design and synthesis of novel benzimidazole derivatives as potential Pseudomonas aeruginosa anti-biofilm agents inhibiting LasR: Evidence from comprehensive molecular dynamics simulation and in vitro investigation. Rehab H. Abd El-Aleam , Ahmed M. Sayed, Mostafa N. Taha, Riham F. George e, Hanan H. Georgey, Hamdy M. Abdel-Rahman. Eur. J. Med. Chem. 241 (2022) 114629.
2- Design, synthesis and anti-Mycobacterium tuberculosis evaluation of new thiazolidin-4-one and thiazolo[3,2-a][1,3,5]triazine derivatives. Mohamed H. Younis, Eman R. Mohammed, Abdalla R. Mohamed, Marwa M. Abdel-Aziz, Hanan H. Georgey, Nagwa M. Abdel Gawad. Bioorg. Chem. 124 (2022) 105807
3- Design and synthesis of ciprofloxacin-sulfonamide hybrids to manipulate ciprofloxacin pharmacological qualities: Potency and side effects. Noha M. Ibrahim, Samar H. Fahim , Mariam Hassan, Awatef E. Farag, Hanan H. Georgey. Eur. J. Med. Chem. 228 (2022) 114021.
4- Bacterial virulence factors: a target for heterocyclic compounds to combat bacterial resistance. Rehab H. Abd El-Aleam, Riham F. George, Hanan H. Georgey and Hamdy M. Abdel-Rahman. RSC Adv., 11 (2021) 36459
5- Synthesis, in vitro anticancer activity and in silico studies of certain pyrazole-based derivatives as potential inhibitors of cyclin dependent kinases (CDKs). Esraa Z. Mohammed , Walaa R. Mahmoud, Riham F. George , Ghaneya S. Hassan, Farghaly A. Omar, Hanan H. Georgey Bioorg. Chem. 115 (2021) 105253
6- Design and synthesis of novel 4-fluorobenzamide-based derivatives as promising anti-inflammatory and analgesic agents with an enhanced gastric tolerability and COX-inhibitory activity. Peter A. Halim, Hanan H. Georgey, Mina Y. George, Ahmed M. El Kerdawy, Mona F. Said, Bioorg. Chem. 116 (2021) 105347.
7- Nanomolar potency of imidazo[2,1‐b]thiazole analogs as indoleamine 2,3‐dioxygenase inhibitors. Menna A. Ewida , Heba A. Ewida , Mahmoud S. Ahmed , Heba Abdelrasheed Allam, Ramzia I. ElBagary, Riham F. George, Hanan H. Georgey, Hussein I. El-Subbagh, Arch. Der. Pharm.354(2021) 2100202
8- 3-Methyl-imidazo[2,1-b]thiazole derivatives as a new class of antifolates: Synthesis, in vitro/in vivo bio-evaluation and molecular modeling simulations. Menna A. Ewida , Heba A. Ewida , Mahmoud S. Ahmed , Heba Abdelrasheed Allam, Ramzia I. ElBagary, Riham F. George, Hanan H. Georgey, Hussein I. El-Subbagh, Bioorg. Chem. 115 (2021) 105205
9- Synthesis and computational studies of novel fused pyrimidinones as a promising scaffold with analgesic, anti-inflammatory and COX inhibitory potential. Mona F. Said, Hanan H. Georgey, Eman R. Mohammed. Eur. J. Med. Chem. 224 (2021) 113682.
10- Mechanistic selectivity investigation and 2D-QSAR study of some new antiproliferative pyrazoles and pyrazolopyridines as potential CDK2 Inhibitors. Ghaneya S. Hassan, Hanan H. Georgey, Esraa Z. Mohammed, Riham F. George, Walaa R. Mahmoud, Farghaly A. Omar. Eur. J. Med. Chem 218 (2021) 113389.
11- Design, synthesis and in silico insights of new 7,8-disubstituted-1,3-dimethyl-1H-purine-2,6(3H,7I)-dione derivatives with potent anticancer and multi kinase inhibitory activities. Abdalla R. Mohamed, Ahmed M. El Kerdawy, Riham F. George, Hanan H. Georgey, Nagwa M. Abdel Gawad. Bioorg. Chem. 107 (2021) 104569
12- Anti-hepatitis-C virus activity and QSAR study of certain thiazolidinone and thiazolotriazine derivatives as potential NS5B polymerase inhibitors. Ghaneya S.Hassan, Hanan H. Georgey, EsraaZ.Mohammed, Farghaly A. Omar. Eur. J. Med. Chem 184 (2019) 111747
13- 1,2,4-Trisubstituted imidazolinones with dual carbonic anhydrase and p38mitogen-activated protein kinase inhibitory activity. Hanan H. Georgey, Fatma M. Manhi, Walaa R. Mahmoud, Nehad A. Mohamed, Emanuela Berrino, Claudiu T. Supuran. Bioorg. Chem. 82 (2019) 109–116
14- Identification of some benzoxazepines as anticancer agents inducing cancer cell apoptosis. Mohamed S Rashad, Hanan H Georgey, Riham F George & Nagwa M Abdel-Gawad. Future Med. Chem. 10(14), 1649–1664(2018).
15- Construction of some cytotoxic agents with aurone and furoaurone scaffolds. Ghaneya S Hassan, Hanan H Georgey, Riham F George & Eman R Mohammed. Future Med. Chem. 10(1), 27–52 (2018).
16- Identification of some novel xanthine-based derivatives with bronchodilator activity. Abdalla R Mohamed, Hanan H Georgey, Riham F George, Wafaa I El-Eraky, Dalia O Saleh & Nagwa M Abdel Gawad. Future Med. Chem. 9(15), 1731–1747 (2017).
17- Synthesis, biological evaluation and molecular modeling study of new (1,2,4-triazole or 1,3,4-thiadiazole)-methylthio-derivatives of quinazolin-4(3H)-one as DHFR inhibitors. Yomna I. El-Gazzar, Hanan H. Georgey, Shahenda M. El-Messery, Heba A. Ewida, Ghada S. Hassan, Marwa M. Raafat, Menna A. Ewida, Hussein I. El-Subbagh. Bioorg. Chem. 72, 282-292 (2017).
18- Synthesis and molecular docking of new imidazoquinazolinones as analgesic agents and selective COX-2 inhibitors. Hassanein H. Hassanein, Hanan H, Georgey, Marwa A. Fouad, Ahmed M. El Kerdawy, Mona F. Said. Future Med. Chem. 9(6),553-578 (2017).
19- Design and synthesis of potent 1,2,4-trisubstituted imidazolinone derivatives with dual p38aMAPK and ERK1/2 inhibitory activity. Fadi M. Awadallah, Sahar M. Abou-Seri, Mohamed M. Abdulla, Hanan H. Georgey. Eur. J. Med. Chem. 94, 397-404 (2015).
20- Synthesis of novel substituted quinazoline and quinazolin-4(3H)-one derivatives of expected antitumor activity. Ghaneya S. Hassan, Hanan H. Georgey, Nashwa A. Ibrahim and Shimaa S. Zakib. Der Pharm. Chem. 7(7),106-119 (2015)
21- Synthesis, Cytotoxic Activity and 2D-QSAR Study of Some Imidazoquinazoline Derivatives. Hanan Georgey. Molecules 19, 3777-3792 (2014).
22- Synthesis of novel 1,3,4-trisubstituted pyrazoles as anti-inflammatory and analgesic agents. Fatma A. Ragab, Nagwa M. Abdel Gawad, Hanan H. Georgey , Mona F. Said. Eur. J. Med. Chem. 63, 645-654 (2013).
23- Synthesis, Anti-inflammatory, Analgesic, Quantitative Structure–Activity Relationship and in Vitro Studies. Fatma A. Ragab, Nagwa M. Abdel Gawad, Hanan H. Georgey, Mona F. Said. Chem. Pharm. Bull., 61(8), 834–845 (2013).
24- Synthesis and antitumor activity of certain2,3,6-trisubstituted quinazolin-4(3H)-one derivatives. Safinaz E. Abbas, Flora F. Barsoum, Hanan H. Georgey, Eman R. Mohammed. Bulletin of Faculty of Pharmacy, Cairo University 51, 273–282 (2013).
25- Novel 1,3,4-heterodiazole analogues: Synthesis and in-vitro antitumor activity. Azza T. Taher, Hanan H. Georgey, Hussein I. El-Subbagh. Eur. J. Med. Chem. 47, 445-451 (2012).
26- Design and synthesis of some pyrazole derivatives of expected anti-inflammatory and analgesic activities. Nagwa M. Abd-El Gawad, Ghaneya S. Hassan, Hanan H. Georgey. Med. Chem. Res. 21, 983–994 (2012).
27- Synthesis of Novel Pyrazole and Dihydropyrazoles Derivatives as Potential Anti- inflammatory and Analgesic Agents. Nagwa M. Abd-El Gawad, Hanan H. Georgey, Nashwa A. Ibrahim, Noha H. Amin, Rania M. Abdelsalam. Arch. Pharm. Res. 35(5), 807-821 (2012).
28- Benzoxepin derivatives: design, synthesis, and pharmacological
evaluation with sedative–hypnotic effect. Nagwa M. Abdel Gawad, Ghaneya S. Hassan, Hanan H. Georgey, Hesham Y. El-Zorba. Med. Chem. Res. 21, 747–759 (2012).
29- Design, synthesis, and anticonvulsant activity of novel quinazolinone analogues. Nagwa M. Abdel Gawad, Hanan Hanna Georgey, Riham M. Youssef, Nehad A. El Sayed. Med. Chem. Res. 20, 1280–1286 (2011).
30- EGFR tyrosine kinase targeted compounds: synthesis, docking study, and in vitro antitumor activity of some new quinazoline and benzo[d]isothiazole derivatives. Kamelia M. Amin, Hanan H. Georgey, Fadi M. Awadallah. Med. Chem. Res. 20, 1042–1053 (2011).
31- Synthesis and antitumor activity of some 2, 3-disubstituted quinazolin-4(3H)-ones and 4, 6- disubstituted- 1, 2, 3, 4-tetrahydroquinazolin-2H-ones. Nagwa M. Abdel Gawad, Hanan H. Georgey, Riham M. Youssef, Nehad A. El-Sayed. Eur. J. Med. Chem.45, 6058-6067 (2010).
32- New Quinazolinone Derivatives: Synthesis,Anti-inflammatory and Antitumor Activities. Safinaz E. Abbas, Nagwa M. Abdel Gawad, Hanan H. Georgey, Jalal H. Abdullah. Int. J. Chem. Tech Res. 2 (3), 1560-1577 (2010).
33- Anti-inflammatory Activity and PGE2 Inhibitory Properties of Novel Phenylcarbamoylmethyl Ester-Containing Compounds. Flora Barsoum, Hanan Georgey, Nagwa Abdel-Gawad. Molecules 14, 667-681(2009).
34- Synthesis and Pharmacological Screening of Certain Imidazoquinazolone Derivatives. Fatma A. Ragab, Hassanein H. Hassanein, Enayat I. Aly and Hanan H. Georgy. Bull. Pharm. Sci., Assiut University 31(1), 29-48 (2008).
35- Synthesis and Anticonvulsant Activity of Some Quinazolin-4-(3H)-one Derivatives. Hanan Georgey, Nagwa Abdel-Gawad, Safinaz Abbas. Molecules 13, 2557-2569 (2008).
36- Synthesis and Anti-inflammatory Activity of Some Imidazol-5(4H)-one Derivatives. Hassanein H. Hassanein, Hanan H. Georgey. Bull. Fac. Pharm. Cairo Univ., 46, 91-102, (2008).
37- Synthesis of Certain Pyrazolo[3,4-d]yrimidine Derivatives of Potential Anti-inflammatory Activity. Safinaz E. Abbas, Hanan H. Georgey, Shimaa M. Abdelrahman, Gamil M. El-Taliawi. Bull. Pharm. Sci., Assiut University, 31(2), 197-214, (2008).
38- Design and Synthesis of certain Imidazo[1,5-a] quinazolin-5(4H)-ones of Anticipated Anticonvulsant activity. Hanan H. Georgey. Egypt J. Chem., 50(4), 455-472 (2007).
39- Synthesis and Antineoplastic activity of certain triazene and triazeno-acridine combilexin derivatives. Samir.M. E. Aly, Hanan H. Georgey, Mohammed A. Mohammed, Nagwa M. Abdel Gawad, Noha H. Amin. Bull. Pharm. Sci., Assiut University, 30(2), 89-110 (2007).
40- New fenamate analogs and imidazoquinazolone derivatives: Synthesis and Anti-inflammatory, Analgesic and Antipyretic activities. Hassanein H. Hassanein, Fatma A.Ragab, Enayat I.Aly, Hanan H. Georgy. Alex. J. Pharm. Sci., 20(2), 129-136 (2006).