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Name: Professor Dr. / Aymen Samir Mohamed Yassin
Department: Microbiology and Immunology  
Email: aymen.yassin@pharma.cu.edu.eg  
Room: D408
C.V.: C.V. File
Scholar: https://scholar.cu.edu.eg/?q=ayassin
Website: https://scholar.cu.edu.eg/?q=ayassin/biocv
Latest List of Publications 1. Immunological characterization of the chemically prepared ghosts of Salmonella Typhimurium as a vaccine candidate. Rabea S, Yassin AS, Mohammed AF, Salem-Bekhit MM, Alanazi FK, Esmail EA, Moneib NA, Hashem AEM. BMC Veterinary Research. Feb 2022:18;18(1):72. doi: 10.1186/s12917-021-03112-4.
2. Draft genome sequence of a prodigiosin-hyperproducing Serratia marcescens strain isolated from Cairo, Egypt. Elkenawy NM, Youssef NH, Aziz RK, Amin MA, Yassin AS. G3 (Bethesda). Sep 27;11(10):jkab284. doi: 10.1093/g3journal/jkab284.2021.
3. Chlorhexidine leads to the evolution of antibiotic-resistant Pseudomonas aeruginosa.Tag ElDein MA, Yassin AS, El-Tayeb O, Kashef MT. Eur J Clin Microbiol Infect Dis. Jun 24. doi: 10.1007/s10096-021-04292-5. 2021.
4. Phenotype-Genotype Characterization and Antibiotic-Resistance Correlations Among Colonizing and Infectious Methicillin-Resistant Staphylococcus aureus Recovered from Intensive Care Units. Nour El-Din HT, Yassin AS, Ragab YM, Hashem AM. Infect Drug Resist. Apr 21;14:1557-1571. doi: 10.2147/IDR.S296000. eCollection 2021.
5. Association of Polymorphism in Survivin Gene and the Risk of Liver Cancer Resulting from Hepatitis C Virus Among Egyptian Patients. Mohamed AA, Yassin AS, Gomaa BS, Darwish H, Mohamed RS, Makled S, Ramdan A, Abd-Elsalam S, Raafat MM. Curr Cancer Drug Targets;21(6):536-543. doi: 10.2174/1568009621666210302090917. 2021.
6. Spatiotemporal Analysis of the Water and Sediment Nile Microbial Community Along an Urban Metropolis.
Eraqi WA, ElRakaiby MT, Megahed SA, Yousef NH, Elshahed MS, Yassin AS. Microb Ecol. Aug;82(2):288-298. doi: 10.1007/s00248-020-01674-8. Epub 2021.
7. Comparative Evaluation of Different Garlic Extracts against Antibiotic Resistant Bacteria. Nagy M., Zaki A. H., Yassin A. S., Salam H.S., Raslan M. Plant Cell Biotechnology and Molecular Biology. Volume 22 [Issue 7-8], 2021.
8. Salmonella-innovative targeting carrier: Loading with doxorubicin for cancer treatment.
Rabea S, Alanazi FK, Ashour AE, Salem-Bekhit MM, Yassin AS, Moneib NA, Hashem AEM, Haq N. Saudi Pharm J. Oct;28(10):1253-1262. doi: 10.1016/j.jsps.2020.08.016. Epub 2020.
9. Digging Deeper into Precision/Personalized Medicine: Cracking the Sugar Code, the Third Alphabet of Life, and Sociomateriality of the Cell. Özdemir V, Arga KY, Aziz RK, Bayram M, Conley SN, Dandara C, Endrenyi L, Fisher E, Garvey CK, Hekim N, Kunej T, Şardaş S, Von Schomberg R, Yassin AS, Yılmaz G, Wang W. OMICS. Feb;24(2):62-80. doi: 10.1089/omi.2019.0220. Epub 2020.
10. An Efficient Method for Endotoxin Removal from Snake Antivenoms. Sheraba N.S., Diab M.R., Yassin A.S., Amin M.A., Zedan H.H. Chromatographia. 83:779–787 https://doi.org/10.1007/s10337-020-03887-y. 2020.
11. Interferon Gamma Release Assay, A Powerful Tool for the Detection of Human and Bovine Tuberculosis in the Greater Cairo Area Compared to Other Diagnostic Tools. Metwally M.A., Yassin A.S., Riad E. M. Hamouda H.M. Amin M. A. Sains Malaysiana 49(4) (785-792 http://dx.doi.org/10.17576/jsm-2020-4904-07. 2020.
12. Comparative Genome-Scale Metabolic Modeling of Metallo-Beta-Lactamase-Producing Multidrug-Resistant Klebsiella pneumoniae Clinical Isolates. Norsigian CJ, Attia H, Szubin R, Yassin AS, Palsson BØ, Aziz RK, Monk JM. Front Cell Infect Microbiol. 2019 May 24;9:161. doi: 10.3389/fcimb.2019.00161. eCollection 2019.
13. Draft Genome Sequences of Four Metallo-Beta-Lactamase-Producing Multidrug-Resistant Klebsiella pneumoniae Clinical Isolates, Including Two Colistin-Resistant Strains, from Cairo, Egypt. Attia H, Szubin R., Yassin A.S., Monk J.M., Aziz R.K. Microbiology Resource Announcements. Feb 8 (7) e01418-18; DOI: 10.1128/MRA.01418-18.2019.
14. A Validation study of the Limulus Amebocyte Lysate test as an end-product endotoxin test for Polyvalent Horse Snake Antivenom. Sheraba N.S., Diab M.R., Yassin A.S., Amin M.A., Zedan H.H. PDA Journal of Pharmaceutical Sciences and Technology. Feb 15. pii: pdajpst.2018.009522. doi: 10.5731/pdajpst.2018.009522.2019.
15. Eraqi W.A., ElRakaiby M.T., Megahed S.A., Yousef N.H., Elshahed M.S., Yassin A.S. The Nile River Microbiome Reveals a Remarkably Stable Community Between Wet and Dry Seasons, and Sampling Sites, in a Large Urban Metropolis (Cairo, Egypt). OMICS: A Journal of Integrative Biology. vol 22(8), PP553-564. 2018.
16. Rabea S., Salem-Bekhit M.M., Alanazi F.K., Yassin A.S., Monieb N.A., Hashem, A.M. A novel protocol for bacterial ghosts’ preparation using tween 80. Saudi Pharmaceutical Journal. Vol 26(2), pp 232-237, 2018.
17. Hashem Y.A., Amin H.M., Essam T.M., Yassin A.S., Aziz R.K. Biofilm formation in enterococci: genotype-phenotype correlations and inhibition by vancomycin. Scientific reports. Jul 18; 7(1):5733, 2017.
18. Elkenawy N.M., Yassin A.S., Elhifnawy H.N., Amin M.A. Optimization of prodigiosin production by Serratia marcescens using crude glycerol and enhancing production using gamma radiation. Biotechnology Reports. Vol. 14, pp 47-53, 2017.
19. Bahy R.H., Hamouda H.M., Shahat A.S., Yassin A.S., Amin M.A. Development and evaluation of a novel vaccine against prevalent invasive multi-drug resistant strains of Streptococcus pneumoniae. PeerJ. Nov 30;4:e2737.2016.
20. Elhosseiny N.M., El-Tayeb O.M., Yassin A.S., Lory S., Attia A.S. The secretome of Acinetobacter baumannii ATCC 17978 type II secretion system reveals a novel plasmid encoded phospholipase that could be implicated in lung colonization. International Journal of Medical Microbiology. Dec; 306(8):633-641. 2016.
21. Bahy R.H., Hamouda H.M., Shahat A.S., Yassin A.S., Amin M.A. Emergence of Neoteric Serotypes Among Multidrug Resistant Strains of Streptococcus pneumoniae Prevalent in Egypt. Jundishapur Journal of Microbiology. Apr 23;9(4), 2016.
22. Eraqi, W.A., Yassin, A.S., Ali, A.E., Amin, A.M. Utilization of Crude Glycerol as a Substrate for the Production of Rhamnolipid by Pseudomonas aeruginosa, Biotechnology Research International. Vol. 2016, Article ID 3464509, 2016.
23. Hassan M, Essam T, Yassin A.S., Salama A. Optimization of rhamnolipid production by biodegrading bacterial isolates using Plackett-Burman design. International Journal of Biological Macromolecules. Jan; 82:573-9, 2016.
24. Sheraba, N.S., Diab, M.R., Yassin, A.S., Amin, M.A., Zedan, H.H. Quality Control Testing for Tracking Endotoxin-Producing Gram-Negative Bacteria during the Preparation of Polyvalent Snake Antivenom Immunoglobulin. PDA Journal of Pharmaceutical Sciences and Technology. Jul-Aug; 69(4):499-510, 2015.
25. Bahy, R.H., Hamouda, H.M., Shahat, A.S., Yassin A.S., Amin, M.A. Serotype identification and antibiotic resistance of the predominant Streptococcus pneumoniae in Egypt. Der Pharmacia Lettre. 7 (11):166-171 2015.
26. Mohamed, A. M., Hashem, A., Yassin, A. S., Elhusseiny E.M., Sleh, M.A., Ahmed, O.A., Shabana, S.S., Ezzat, O. Human Aldehyde Dehydrogenase (ALDH) in Cirrhotic and Hepatocellular Carcinoma Patients Related to Hepatitis C Virus. Journal of Gastroenterology and Hepatology Research. 4(10): 1792-1796, 2015.
27. Moneib, N.A., Amin, H.M., Yassin A.S., El-Hossary D., Jiman-Fatani, A. Characterization of Acinetobacter bumannii clinical isolates from King AbdulAziz University Hospital in Jeddah, Saudi Arabia. New Egyptian Journal of Microbiology, (42), 111-121, 2015.
28. Farag, M.A., Al-Mahdy, D.A., Salah, El Dine R., Fahmy, S., Yassin, A.S., Porzel, A., Brandt, W. Structure-Activity Relationships of Antimicrobial Gallic Acid Derivatives from Pomegranate and Acacia Fruit Extracts against Potato Bacterial Wilt Pathogen. Chemistry and Biodiversity. Jun; 12(6):955-62, 2015.
29. Elhosseiny, N. M., Amin, M.A., Yassin, A.S., and Attia, A.S. Acinetobacter baumannii universal stress protein A plays a pivotal role in stress response and is essential for pneumonia and sepsis pathogenesis. International journal of Medical Microbiology. Vol. 305, issue 1:114-23, 2015
30. Hashem, Y. A., Yassin, A.S., and Amin, M. A. Molecular characterization of Enterococcus spp. clinical isolates from Cairo, Egypt. Indian Journal of Medical Microbiology. Vol. 33 Suppl: S80-6, 2015
31. Raouf, H. E., Yassin, A.S., Megahed, A.S., Ashour, M.S. and Mansour, T.M. "Seroprevalence of occult hepatitis B among Egyptian paediatric hepatitis C cancer patients. Journal of viral hepatitis. Vol. 22, issue 2: 101-9, 2015.
32. El-Batal, A. I., ElKenawy, N. M., Yassin A.S., and Amin M.A., "Laccase production by Pleurotus ostreatus and its application in synthesis of gold nanoparticles", Biotechnology Reports. Vol. 5: 31 - 39, 2015.
33. Shaikh T.R., Yassin A.S., Lu Z., Barnard D., Meng X., Lu T.M., Wagenknecht T., Agrawal R.K. Initial bridges between two ribosomal subunits are formed within 9.4 milliseconds, as studied by time-resolved cryo-EM. Proceedings in the National Academy of Science U S A. 111(27):9822-7. Jul 8; (2014).
34. Lu, Z., Barnard, D., Shaikh, T.R., Meng, X., Mannella, C.A, Yassin, A.S., Agrawal, A., Wagenknecht, T. and Lu. T.M. Gas-Assisted Annular Microsprayer for Sample Preparation for Time-Resolved Cryo-Electron Microscopy. Journal of micromechanics and microengineering: structures, devices, and systems. Vol. 24, issue 11: 115001, 2014.
35. Metwally, M. A., Yassin, A. S., Essam, T. M. Hamouda, H. M. and Amin, M. A. Detection, characterization, and molecular typing of human Mycoplasma spp. from major hospitals in Cairo, Egypt. The Scientific World Journal. Vol. 2014:549858. 2014.
36. Sheraba, N. S., Yassin, A.S., Fahmy, A. and Amin, M.A. Quantitative suspension tests for the evaluation of bactericidal, fungicidal and sporicidal effects of biocides used in vaccine production facility. African Journal of Microbiology Research. Vol. 8, issue 5: 417-424, 2014.
37. Hassan M., Essam T., Yassin A.S., Salama A. Screening of Bio-Surfactant Production Ability among Organic Pollutants Degrading Isolates Collected From Egyptian Environment. Journal of Microbial and Biochemical Technology. Vol 6: 195-201, 2014.
38. Sheraba, N.S., Diab, M.R., Yassin, A.S., Amin, M.A., Zedan, H.H. Detection of endotoxin producing GramNegative bacteria through an enviromental monitoring program applied in an antisera prepartion plant. Egyptian Journal of Biomedical Sciences. (45), 211-224, 2014.
39. Ramadan M.A., Megahed S.A., Eltaweel K.M. and Yassin AS. Potential in vitro anti-helicobacter activity of bacteriocin and bacteriocin-like compounds produced by lactobacilli. The Journal of Microbiology, Biotechnology and Food Sciences. Vol 4, No 2, Oct-Nov, 2014.
40. Raouf, H.E., Yassin A.S., Soliman A.H, Mansour M.T., Megahed, S.A., Ashour, M.S. Epidemiologic study on the prevalence of occult hepatitis B virus among cancer and non-cancer HCV among pediatric patients. New Egyptian Journal of Microbiology. (38), 1-15, 2014.
41. Elwa H.E., Yassin, A.S., Hussein H.B., Amin, M.A., Meguid, N.A. Cytomegalovirus infections among low birth weight infants in a major hospital in Cairo Egypt, (Elgalae). New Egyptian Journl of Microbiology. (39):30-41, 2014.
42. Yassin, A., Tawfeek,M., Hashem, R., Nagy, Y., Hashem, Y., Salam,S.A., Emad, A., Ragab, Y., Kholiefy, A. Shawky, A., et al., Antibiotic resistance patterns among common Gram positive and Gram negative pathogens in clinical isolates from major hospitals in Cairo, Egypt. Worldwide Research Efforts in the Fighting against Microbial Pathogens: From Basic Research to Technological Developments, Boca Raton, Florida, USA, BrownWalker Press, pp. 34-39, 2013.
43. Ayoub, E.A., Shafik, C.F., Gaynor, A.M. Mohareb, E.W., Amin, M.A., Yassin, A.S., El-Refaey, S., Genedy, M. and Kandeel, A. A molecular investigative approach to an outbreak of acute hemorrhagic conjunctivitis in Egypt, October 2010. Virology Journal. Vol. 10, 2013.
44. Hashem, R. A., Yassin, A.S., Zedan, H.H., and Amin,M.A. Fluoroquinolone resistant mechanisms in methicillin-resistant Staphylococcus aureus clinical isolates in Cairo, Egypt, Journal of Infection in Developing Countries. Vol. 7, issue 11: 796-803, 2013.
45. Shafik, C.F., Mohareb, E.W., Yassin, A.S., Amin, M.A., ElKholy, A., El-Karsasky, H. and Youssef, F.G. Viral Etiologies of lower respiratory tract infections among Egyptian children under five years of age. BMC Infectious Diseases. Vol 13; 12:350, 2012.
46. Kashef, M.T., Yassin, A.S., and Hosny, A.M.S. Detection of β- Lactamse genes in Bacillus cereus isolated from food samples in Egypt. Journal of Microbiological Methods. Vol 91, Issue 3, Pages 354–357, 2012.
47. Mohsen, D.H, Yassin, A.S., Aziz, R.K. and Amin, M.A. Detection of β- Lactamse genes in Bacillus cereus isolated from food samples in Egypt. New Egyptian Journal of Microbiology. Vol. 33, pages 11-22, 2012.
48. Sheraba, N.S., Yassin, A.S., Fahmy, A. and Amin, M.A. Efficacy and toxicity of neutralizers against disinfectants and antiseptics used in vaccine production facility. African Journal of Microbiology Research. Vol. 6(36): 6565-6571, 20, 2012.
49. Suzan, M.R., Yassin, A.S. And Amin, M.A. The application of uniplex, duplex, and multiplex PCR for the absence of specified microorganism testing of pharmaceutical excipients and drug products. PDA Journal of Pharmaceutical Sciences and Technology. 66(4):307-17, 2012.
50. Yassin, A.S., Agrawal, R. K., and Banavali N., K. Computational Exploration of Structural Hypotheses for an Additional Sequence in a Mammalian Mitochondrial Protein. PLOS ONE. 6(7): e21871. 2011.
51. Agrawal, R.K., Sharma, M.R., Yassin, A., Lahiri, I., and Spremulli, L.L. Structure and function of organellar ribosomes as revealed by cryo-EM. In "Ribosomes: Structure, Function, and Dynamics," Rodnina, M.,Wintermeyer, W., & Green, R. eds. (SpringerWien, New York), pp. 83-96, 2011.
52. Yassin, A.S., Haque Md., Datta P.P., Elmore, K., Banavali, N.K., Spremulli, L. L., and Agrawal, R. K. Insertion domain within mammalian mitochondrial translation initiation factor 2 serves the role of eubacterial initiation factor 1 Proceedings in the National Academy of Science U S A. 108(10):3918-23, 2011.
53. Sheraba, N.S., Yassin, A.S., and Amin, M.A. High-Throughput Molecular Identification of Staphylococcus spp. Isolated from a Clean Room Facility in an Environmental Monitoring Program. BMC research Notes, 4; 3:278, 2010.
54. Lu, Z., Shaikh, T., Barnard, D., Meng, X., Mohamed, H., Yassin, A., Mannella, C., Agrawal, R., Lu, T. and Wagenknecht, T. Monolithic Microfluidic Mixing-Spraying Devices for Time-Resolved Cryo-EM, Journal of Structural Biology, 168 (3), 388-395, 2009.
55. Yassin, A. and Mankin, A. S. Potential New Antibiotic Sites In the Ribosome Revealed By Deleterious Mutations in RNA of the Large Ribosomal Subunit. Journal of Biological Chemistry. 282, 24329-24342, 2007.
56. Yassin, A., Fredrick, K. and Mankin, A. S. Deleterious Mutations in Small Subunit Ribosomal RNA identify Functional Sites and Potential Targets for Antibiotics. Proceedings in the National Academy of Science U S A. 102, 16620-16625, 2005.
57. Polacek, N., Gaynor, M., Yassin, A. and Mankin, A. S. Ribosomal Peptidyl Transferase can withstand Mutations at the Putative Catalytic Nucleotide. Nature 411, 498-501, 2001.
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