Assistant Professor Dr. / Samar Hashem Fahim
Pharmaceutical Chemistry
samer.mohamed@pharma.cu.edu.eg
C-705
Latest List of Publications
1. Synthesis and anti-inflammatory activity of novel pyrimido[1,6-a]azonine and pyrimido[4,5:4,5]pyrimido[1,6-a]azonine derivatives. Ragab, F.A., Hanna, M.M., Barsoum, F.F., Fahim S.H., Ebeid, M.Y., Salem, H.A. Egypt J. Chem. (2007) Vol. 50 (1), 53-66.
2. Synthesis of some novel pyrido[3,2-e]pyrrolol[1,2-c]pyrimidine derivatives of expected anti-inflammatory activity. Ragab, F.A., Hanna, M.M., Barsoum, F.F., Fahim S.H., Ebeid, M.Y., Salem, H.A. Egypt J. Chem. (2007) Vol. 50 (1), 105-116.
3. Application of hydrazine and hydrazido linkers to connect Benzene-sulfonamides with hydrophilic/phobic tails for targeting the middle region of human carbonic anhydrases active site: Selective inhibitors of hCA IX. Heba Abdelrasheed Allam, Samar H. Fahim, Mahmoud F.Abo-Ashour, Alessio Nocentini, Mohamed E. Elbakry, Mohamed A. Abdelrahman, Wagdy M. Eldehna, Hany S. Ibrahim , Claudiu T. Supuran. European Journal of Medicinal Chemistry (2019) Vol. 179, 547-556.
4. New ibuprofen derivatives as H2S and NO donors as safer anti-inflammatory agents. Ghaneya S Hassan, Gehan H Hegazy, Noha M Ibrahim and Samar H Fahim. Future Medicinal Chemistry (2019) Vol. 11 (23), 3029-3045.
5. Synthesis, biological and molecular dynamics investigations with a series of triazolopyrimidine/triazole-based benzenesulfonamides as novel carbonic anhydrase inhibitors. Mohamed A. Said, Wagdy M. Eldehna, Alessio Nocentini, Alessandro Bonardi, Samar H. Fahim, Silvia Bua, Dalia H. Soliman, Hatem A. Abdel-Aziz, Paola Gratteri, Sahar M. Abou-Seri, Claudiu T. Supuran. European Journal of Medicinal Chemistry (2020) Vol. 185,111843.
6. Sulfonamide-based Ring-fused analogues for CAN508 as novel carbonic anhydrase inhibitors endowed with antitumor activity: Design, synthesis, and in vitro biological evaluation. Mohamed A. Said, Wagdy M. Eldehna, Alessio Nocentini, Samar H. Fahim, Alessandro Bonardi, Dalia H. Soliman, Abdullah A. Elgazar, Vladimír Kryštof, Hatem A. Abdel-Aziz, Paola Gratteri, Sahar M. Abou-Seri, Claudiu T. Supuran. European Journal of Medicinal Chemistry (2020) Vol. 189,112019.
7. Synthesis and biological evaluation of new coumarin derivatives as cytotoxic agents. Fatma A. Ragab, Amal A. M. Eissa, Samar H. Fahim, Mohammad A. Salem, Mona A. Gamal, Yassin M. Nissan. Archiv der Pharmazie (2021) Vol. 354 (8), 2100029.
8. Novel coumarin–pyrazoline hybrids: synthesis, cytotoxicity evaluation and molecular dynamics study. Fatma A. Ragab, Amal A. M. Eissa, Samar H. Fahim, Mohammad Alaraby Salem, Mona A. Gamal and Yassin M. Nissan. New Journal of Chemistry (2021), vol 45, 19043-19055.
9. Design and synthesis of ciprofloxacin-sulfonamide hybrids to manipulate ciprofloxacin pharmacological qualities: Potency and side effects. Noha M. Ibrahim, Samar H. Fahim, Mariam Hassan, Awatef E. Farag, Hanan H. Georgey. European Journal of Medicinal Chemistry (2022) Vol. 228, 114021.
10. Nonacidic thiophene‐based derivatives as potential analgesic and design, synthesis, biological evaluation, and metabolic stability study. Demiana S. Mikhail, Hala B. El‐Nassan, Sally T. Mahmoud, Samar H. Fahim. Drug Development Research (2022) Vol. 83 (8),1739-1757.