Assistant Professor Dr. / Suzan Mohamed Mansour
Pharmacology and Toxicology
suzan.mansour@pharma.cu.edu.eg
Latest List of Publications
- Vitamin D and rosuvastatin alleviate type-II diabetes-induced cognitive dysfunction by modulating neuroinflammation and canonical/noncanonical Wnt/β-catenin signaling. Muhammad Muneeb, Suzan M. Mansour, Samira Saleh, Reham A. Mohammed. PLOS ONE 2022. https://doi.org/10.1371/journal.pone.0277457
- Zofenopril antitumor activity in mice bearing Ehrlich solid carcinoma: Modulation of PI3K/AKT signaling pathway. Suzan M. Mansour, Rasha Y. Ibrahim. Brazilian Journal of Pharmaceutical Sciences 2022; 58. https://doi.org/10.1590/s2175-97902022e19922
- Artificial intelligence-assisted development of in situ forming nanoparticles for arthritis therapy via intra-articular delivery. Ahmed S. Yacoub, Hussein O. Ammar, Magdy Ibrahim, Suzan M. Mansour, Nada M. El Hoffy. Drug Delivery 2022 Dec; 29 (1): 1423-1436. doi: 10.1080/10717544.2022.2069882.
- Repositioning of Ticagrelor: Renoprotection mediated by modulating renin-angiotensin system, inflammation, autophagy and galectin-3. Suzan M. Mansour, Abd El-Aal SA, El-Abhar HS, Ahmed KA, Awny MM. Eur J Pharmacol. 2022 Jan 29:174793. doi: 10.1016/j.ejphar.2022.174793. Online ahead of print.
- Vitamin D Combined with Pioglitazone Mitigates Type-2 Diabetes-induced Hepatic Injury Through Targeting Inflammation, Apoptosis, and Oxidative Stress. Hamouda HA, Suzan M. Mansour, Elyamany MF. Inflammation. 2022 Feb; 45(1):156-171. doi: 10.1007/s10753-021-01535-7.
- Tadalafil and bergapten mitigate streptozotocin-induced sporadic Alzheimer's disease in mice via modulating neuroinflammation, PI3K/Akt, Wnt/β-catenin, AMPK/mTOR signaling pathways. Salem MA, Budzyńska B, Kowalczyk J, El Sayed NS, Suzan M. Mansour. Toxicol Appl Pharmacol. 2021 Oct 15; 429:115697. doi: 10.1016/j.taap.2021.115697.
- Safety of inhaled ivermectin as a repurposed direct drug for treatment of COVID-19: A preclinical tolerance study. Suzan M Mansour, Rehab N Shamma, Kawkab A Ahmed, Nirmeen A Sabry, Gamal Esmat, Azza A Mahmoud, Amr Maged. Int Immunopharmacol. Oct; 99: 108004. doi: 10.1016/j.intimp.2021.108004. Epub 2021 Jul 23.
- Formulation and optimization of sildenafil citrate-loaded PLGA large porous microparticles using spray freeze-drying technique: A factorial design and in-vivo pharmacokinetic study. Hend Shahin, Bhavani P. Vinjamuri, Azza A. Mahmoud, Suzan M. Mansour, Mahavir Chougule, Lipika Chablani. DOI: 10.1016/j.ijpharm.2021.120320. 2021 Mar 15; 597: 120320.
- Sodium hydrogen sulfide upregulates cystathionine 𝛽-synthase and protects striatum against 3-Nitropropionic acid-induced neurotoxicity in rats. Reham A. Mohammed, Suzan M. Mansour. Journal of Pharmacy and Pharmacology. 2021 Mar 6;73(3):310-321. doi: 10.1093/jpp/rgaa072.
- Protective effect of sitagliptin and whole body gamma irradiation in diabetes-induced cardiac injury. Suzan M. Mansour, Sara Aly, Seham H.M. Hassan, Hala F. Zaki. Canadian Journal of Physiology and Pharmacology. 2021 Jun;99 (6):676-684. doi: 10.1139/cjpp-2020-0454.
- MiR‑200a inversely correlates with Hedgehog and TGF‑β canonical/ non‑canonical trajectories to orchestrate the anti‑fibrotic effect of Tadalafil in a bleomycin‑induced pulmonary fibrosis model. Suzan M. Mansour, Hanan S. El‑Abhar, Ayman A. Soubh. Inflammopharmacology. 2021 Feb;29(1):167-182. doi: 10.1007/s10787-020-00748-w.
- The Effect of Liver and Kidney Disease on the Pharmacokinetics of Clozapine and Sildenafil: A Physiologically Based Pharmacokinetic Modeling. Amira M Ghoneim, Suzan M. Mansour. Drug Design, Development and Therapy 2020 (14): 1469-1479. DOI: 10.2147/DDDT.S246229.
- Phytochemical profile and protective effect of Ocimum basilicum aqueous extract in doxorubicin/irradiation-induced testicular injury. Rasha Y. M. Ibrahim, Suzan M. Mansour, Wafaa M. Elkady. Journal of Pharmacy and Pharmacology 72 (1): 101-110. DOI: 10.1111/jphp.13175
- Design and evaluation of novel inhalable sildenafil citrate spray-dried microparticles for pulmonary arterial hypertension. Hend I. Shahin, Bhavani Prasad Vinjamuri, Azza A. Mahmoud, Rehab N. Shamma, Suzan M. Mansour, Hussein O. Ammar, Mahmoud M. Ghorab, Mahavir Bhupal Chougule, Lipika Chablani. Journal of Controlled Release 302: 126-139. DOI: 10.1016/j.jconrel.2019.03.029.
- Venlafaxine alleviates complete Freund's adjuvant-induced arthritis in rats: Modulation of STAT-3/IL-17/RANKL axis. Kamel M. Kamel, Amany M. Gad, Suzan M. Mansour, Marwa M. Safar, Hala M. Fawzy. Life Sciences 226: 68-76. DOI: 10.1016/j.lfs.2019.03.063.
- Novel Anti-arthritic Mechanisms of Polydatin in Complete Freund’s Adjuvant-Induced Arthritis in Rats: Involvement of IL-6, STAT-3, IL-17, and NF-кB. Kamel M. Kamel, Amany M. Gad, Suzan M. Mansour, Marwa M. Safar, Hala M. Fawzy. Inflammation 41(): 1974-1986. DOI: 10.1007/s10753-018-0841-4
- Chromium picolinate and rosiglitazone improve biochemical derangement in a rat model of insulin resistance: Role of TNF-α and leptin. Suzan M. Mansour, Hala F. Zaki and Ezz-El-Din El-Denshary. Pharmacologia 4 )3): 186-196. DOI: 10.5567/pharmacologia.2013.186.196.
- Beneficial effects of co-enzyme Q10 and rosiglitazone in fructose-induced metabolic syndrome in rats. Suzan M. Mansour, Hala F. Zaki and Ezz-El-Din El-Denshary. BFOPCU 51 (1): 13-21. DOI: 10.1016/j.bfopcu.2012.10.001.
- Ginkgo biloba extract (EGb 761) normalizes hypertension in 2K, 1C hypertensive rats: Role of antioxidant mechanisms, ACE inhibiting activity and improvement of endothelial dysfunction. Suzan M. Mansour, Ashraf K. Bahgat, Aiman S. El-Khatib, Mohamed T. Khayyal. Phytomedicine 1 18(8-9): 641-647. DOI: 10.1016/j.phymed.2011.01.014.