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Professor Dr. / Mahmoud Hassan Mahmoud Teaima
Pharmaceutics and Industrial Pharmacy
mahmoud.teaima@pharma.cu.edu.eg

Latest List of Publications

1. “Enhancement of Dissolution of Glimepiride using Solid Dispersion. ”Poster presented at the Scientific Conference of Faculty of Pharmacy, Cairo, Egypt 2006.
2. “Enhancement of Dissolution of Glimepiride using Inclusion complexes with β-hydroxycyclodextrin.” Poster presented at the Egyptian Pharmaceutical Society Conference, Cairo, Egypt 2007.
3. “Formulation and Evaluation of Modified Glimepiride Tablets in hairless Albino Rat Skin ” Poster presented at the American Association of Pharmaceutical Sciences Conference, New Orleans, USA 2008.
4. “Enhanced Iontophoretic Transdermal Delivery of Escin through Hairless Albino Rat Skin.” Paper Published at the International Journal of Pharmacy and Pharmaceutical Sciences 2012.
5. “Evaluation of the Microcirculatory Efficacy of Iontophoretic Topical Treatment with Escin Gel(s) in Healthy Human” Poster presented at the American Association of Pharmaceutical Sciences Conference, New Orleans, USA 2012.
6. HPLC–DAD–MS/MS profiling of standardized rosemary extract and enhancement of its anti-wrinkle activity by encapsulation in elastic nanovesicles. Archives of Pharmacal Research 2016.
7. Transdermal delivery of vancomycin hydrochloride using combination of nanoethosomes and iontophoresis: in vitro and in vivo study. Drug Delivery Journal 2016.
8. HPLC–DAD–MS/MS profiling of standardized rosemary extract and enhancement of its anti-wrinkle activity by encapsulation in elastic nanovesicles. Archives of Pharmacal Research 2016.
9. Formulation, release characteristics, and bioavailability study of gastroretentive floating matrix tablet and floating raft system of Mebeverine HCl. Drug Design, Development and Therapy 2017.
10. Non-ionic surfactant based vesicular drug delivery system for topical delivery of caffeine for treatment of cellulite: design, formulation, characterization, histological anti-cellulite activity, and pharmacokinetic evaluation. Drug Development and Industrial Pharmacy 2017.
11. Dual-purpose vardenafil hydrochloride/dapoxetine hydrochloride orodispersible tablets: in vitro formulation/evaluation, stability study and in vivo comparative pharmacokinetic study in healthy human subjects. Drug Development and Industrial Pharmacy 2018.
12. Pomegranate extract-loaded solid lipid nanoparticles: design, optimization, and in vitro cytotoxicity study. International Journal of Nanomedicine 2018.
13. Formulation, Evaluation and Antioxidant activity of Caffeine Fast Melt Tablets. Research Journal of Pharmacy and Technology 2018.
14. Cubosomal based oral tablet for controlled drug delivery of telmisartan: formulation, invitro evaluation and in-vivo comparative pharmacokinetic study in rabbits. Drug Development and Industrial Pharmacy 2019.
15. Bioavailability enhanced clopidogrel -loaded solid SNEDDS: Development and in-vitro/invivo characterization. Journal of Drug Delivery Science and Technology 2019.
16. Natamycin niosomes as a promising ocular nanosized delivery system with ketorolac tromethamine for dual effects for treatment of candida rabbit keratitis; in vitro/in vivo and histopathological studies. Drug Development and Industrial Pharmacy 2019.
17. Optimization of nano spray drying parameters for production of α-amylase nanopowder for biotheraputic applications using factorial design. Drying Technology 2019.
18. Formulation and In-vitro Characterization of Self Nano-emulsifying Drug Delivery System (SNEDDS) for enhanced Solubility of Candesartan Cilexetil. Research Journal of Pharmacy and Technology 2019.
19. Assessment Of Spanlastic Vesicles Of Zolmitriptan For Treating Migraine In Rats. Drug Design, Development and Therapy 2019.
20. Proniosomal Telmisartan Tablets: Formulation, in vitro Evaluation and in vivo Comparative Pharmacokinetic Study in Rabbits. Drug Design, Development and Therapy 2020.
21. Niosomes: Do They Increase the Potency of Topical Natamycin Ketorolac Formula in Treating Aspergillus Keratitis? An Experimental Study. Journal Of Ocular Pharmacology And Therapeutics 2020.
22. A validated HPLC-DAD method for simultaneous determination of major bioactive constituents of Antidiabetic herbal extracts; application to a newly Co-formulated nutraceutical product. Microchemical Journal 2020.
23. Development of Pomegranate Extract-Loaded Solid Lipid Nanoparticles: Quality by Design Approach to Screen the Variables Affecting the Quality Attributes and Characterization. ACS Omega 2020.
24. Eco-friendly synthesis of functionalized chitosan-based nanoantibiotic system for potential delivery of linezolid as antimicrobial agents. Saudi Pharmaceutical Journal 2020.
25. Fabrication, characterization and biological evaluation of silymarin nanoparticles against carbon tetrachloride-induced oxidative stress and genotoxicity in rats. International Journal of Pharmaceutics 2020.
26. Formulation and evaluation of niosomal vesicles containing ondansetron HCL for transmucosal nasal drug delivery. Drug Development and Industrial Pharmacy 2020.
27. Freeze-Dried Clopidogrel Loaded Lyotropic Liquid Crystal: Box-Behnken Optimization, In-Vitro and In-Vivo Evaluation. Current Drug Delivery 2020.
28. Promising Swellable Floating Bupropion Tablets: Formulation, in vitro/in vivo Evaluation and Comparative Pharmacokinetic Study in Human Volunteers. Drug Design, Development and Therapy 2020.
29. Formulation, Characterization and Comparative Pharmacokinetic Study of Bupropion Floating Raft System as a Promising Approach for Treating Depression. Journal of Pharmaceutical Sciences 2020.
30. A Promising Single Oral Disintegrating Tablet for Co-Delivery of Pitavastatin Calcium and Lornoxicam Using Co-Processed Excipients: Formulation, Characterization and Pharmacokinetic Study. Drug Design, Development and Therapy 2021.
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32. Transdermal Delivery of Telmisartan: Formulation, in vitro, ex vivo, Iontophoretic Permeation Enhancement and Comparative Pharmacokinetic Study in Rats. Drug Design, Development and Therapy 2021.
33. Binge Eating Disorders; Updated and Emerging Approaches. International Journal of Applied Pharmaceutics 2021.
34. Enhanced Transdermal Delivery of Bisoprolol Hemifumarate via Combined Effect of Iontophoresis and Chemical Enhancers: Ex Vivo Permeation/In Vivo Pharmacokinetic Studies. Pharmaceutics 2021.
35. Formulation and Characterization of Acetazolamide/Carvedilol Niosomal Gel for Glaucoma Treatment: In Vitro, and In Vivo Study. Pharmaceutics 2021.
36. Liver Targeting of Daclatasvir via Tailoring Sterically Stabilized Bilosomes: Fabrication, Comparative In Vitro/In Vivo Appraisal and Biodistribution Studies. International Journal of Nanomedicine 2021.
37. Pharmaceutical policies and regulations of oral antiviral drugs for treatment of hepatitis C in Egypt—case study. Journal of Pharmaceutical Policy and Practice 2021.
38. Simultaneous Optimization of Oral and Transdermal Nanovesicles for Bioavailability Enhancement of Ivabradine Hydrochloride. International Journal of Nanomedicine 2021.
39. A Review on Advances in The Development of Spermicides Loaded Vaginal Drug Delivery System: State of The Art. International Journal of Applied Pharmaceutics 2022.
40. Bi-Laminated Oral Disintegrating Film for Dual Delivery of Pitavastatin Calcium and Lornoxicam: Fabrication, Characterization and Pharmacokinetic Study. International Journal of Applied Pharmaceutics 2022.
41. Clove Oil Endorsed Transdermal Flux of Dronedarone Hydrochloride Loaded Bilosomal Nanogel: Factorial Design, In vitro Evaluation and Ex vivo Permeation. AAPS PharmSciTech 2022.
42. Comprehensive Overview on Recent Updates of Gastroretentive Raft-Forming Systems. International Journal of Applied Pharmaceutics 2022.
43. Construction of sublingual trilaminated Eszopiclone fast dissolving film for the treatment of Insomnia: Formulation, characterization, and In vivo clinical comparative pharmacokinetic study in healthy human subjects. PLOS ONE 2022.
44. Design and Optimization of Pioglitazone Hydrochloride Self-Nanoemulsifying Drug Delivery System (SNEDDS) Incorporated into an Orally Disintegrating Tablet. Pharmaceutics 2022.
45. Efficacy of pomegranate extract loaded solid lipid nanoparticles transdermal emulgel against Ehrlich ascites carcinoma. Nanomedicine: Nanotechnology, Biology, and Medicine 2022.
46. Formulation And Characterization of ODT Using Different Co-Process Containing Daclatsvir: In Vitro And In Vivo Pharmacokinetics Study on Healthy Volunteers for Hepatitis C Treatment. International Journal of Applied Pharmaceutics 2022.
47. Ion-Triggered In Situ Gelling Intranasal Spray of Dronedarone Hydrochloride Nanocarriers: In Vitro Optimization and In Vivo Pharmacokinetic Appraisal. Pharmaceutics 2022.
48. Lipid based nanoparticles as a novel treatment modality for hepatocellular carcinoma: a comprehensive review on targeting and recent advances. Journal of Nanobiotechnology 2022.
49. Niosomes Versus Proniosomes as Promising Drug Delivery Systems in Treatment of Diabetes Mellitus. International Journal of Applied Pharmaceutics 2022.
50. Screening of Adapalene Microsponges Fabrication Parameters with Insight on the In vitro Biological Effectiveness. Drug Design, Development and Therapy 2022.
51. Sertaconazole-Nitrate-Loaded Leciplex for Treating Keratomycosis: Optimization Using D-Optimal Design and In Vitro, Ex Vivo, and In Vivo Studies. Pharmaceutics 2022.
52. Transethosomes As Breakthrough Tool For Controlled Transdermal Delivery Of Dexketoprofen Trometamol: Design, Fabrication, Statistical Optimization, In Vitro, And Ex Vivo Characterization. . International Journal of Applied Pharmaceutics 2022.
53. Utilization of propranolol hydrochloride mucoadhesive invasomes as a locally acting contraceptive: in-vitro, ex-vivo, and in-vivo evaluation. Drug Delivery 2022.
54. Wound healing activities of polyurethane modified chitosan nanofibers loaded with different concentrations of linezolid in an experimental model of diabetes. Journal of Drug Delivery Science and Technology 2022.
55. Formulation of novel niosomal repaglinide chewable tablets using coprocessed excipients: in vitro characterization, optimization and enhanced hypoglycemic activity in rats. Drug Delivery 2023.
56. Integration of terpesomes loaded Levocetrizine dihydrochloride gel as a repurposed cure for Methicillin-Resistant Staphylococcus aureus (MRSA)-Induced skin infection; Doptimal optimization, ex-vivo, in-silico, and in-vivo studies. International Journal of Pharmaceutics 2023.
57. Lyophilized Nasal Inserts of Atomoxetine HCl Solid Lipid Nanoparticles for Brain Targeting as a Treatment of Attention-Deficit/Hyperactivity Disorder (ADHD): A Pharmacokinetics Study on Rats. Pharmaceuticals 2023.
58. Merging konjac glucomannan with other copolymeric hydrogels as a cutting-edge liquid raft system for dual delivery of etoricoxib and famotidine. Drug Delivery 2023.
59. Oral Bioavailability Enhancement of Vancomycin Hydrochloride with Cationic Nanocarrier (Leciplex): Optimization, In Vitro, Ex Vivo, and In Vivo Studies. Scientia Pharmaceutica 2023.
60. PEGylated Tween 80-functionalized chitosan- lipidic nano-vesicular hybrids for heightening nose-to-brain delivery and bioavailability of metoclopramide. Drug Delivery 2023.
61. The deleterious effect of xylene-induced ear edema in rats: Protective role of dexketoprofen trometamol transdermal invasomes via inhibiting the oxidative stress/NF κB/COX-2 pathway. International Journal of Pharmaceutics 2023.
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