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Professor Dr. / Azza Taher Taher Shalaby
Pharmaceutical Organic Chemistry

Latest List of Publications

1) Novel pyrazolone derivatives synthesis and evaluation of analgesic activity.
Mohammed A. Shabaan, Salwa El-Meligi and Azza Taher
Alex. J. Pharm. Sci., 4(1), 93-95(1990).
2) Synthesis of certain pyrazolo(1,5-d)1,2,4-triazines.
Mohammed A. Shabaan, Salwa El-Meligi and Azza Taher
Bull. Fac. Pharm. Cairo Univ. , 28(3), 19-22(1990).
3) Novel Pyrazolidine – 3,5- dione derivatives, Synthesis as anti-inflammatory activity.
Azza Taher, Osama El-Badry, Mohammed Essawi, Hamdy Ragab and Mansour Khalifa
Bull. Fac. Pharm. Cairo Univ., 39(3), 25-33(2001).

4) Synthesis of some floctafenine derivatives of Expected anti-inflammatory/ analgesic activity.
Gehan Hegazy, Azza Taher and Asmaa Zaher
Arch. Der Pharmazie, 338, 374-384 (2005).

5) Imidazo (1,2-b) pyrazole- 2,6-dione; Synthesis and Preliminary evaluation of anti-inflammatory and analgesic activity.
Azza Taher* and Mohammed Raafat
43(2), 43-55 (2005). Bull. Fac. Pharm. Cairo Univ.

6) Synthesis of Certain Thienopyrimidine Derivatives of Possible Pharmaceutical Interest.
Ashraf Moneer, Azza Taher* and Hanan Kadry
Bull. Fac. Pharm. Cairo Univ. ,45(3), 66-78 (2007).

7) Design, synthesis and blood pressure lowering activity of certain tetrahydrobenzothiophene derivatives with arylpiperazinyl side chains. Khalid Abouaid, Azza Taher and Mona Kamel
Bull. Fac. Pharm. Cairo Univ. ,45(2), 44-51 (2007).

8) Design and Synthesis of some floctafenine derivatives of expected selective COX2 inhibitor activity.
Azza Taher*, Gihan Hegazy, Lamiaa Hammad and Mohammed Elyamani
Bull. Fac. Pharm. Cairo Univ. ,45(2), 52-60 (2007).

9) Design, Synthesis and anti-hypertensive activity of certain pyrazolo- pyrimidine with arylpiperazine side chain.
Khaled Abouzid, Azza Taher* and Hanan Kadry Bull. Fac. Pharm. Cairo Univ. ,45(2), 61-71 (2007)

10) Synthesis of certain 1,2,4-triazolo[4,3-a]quinoxalinone derivatives for evaluation of in-vitro antitumor and antimicrobial activities.
Azza T. Taher* , Nadia Khalil and Eman Ahmed
Bull. Fac. Pharm. Cairo Univ., 47(1), 19-26 (2009).

11) Synthesis of novel 3,4-dihydroquinoxalin-2(1H-one derivatives . Mohammed Shabaan, Azza T. Taher* and Eman Omar
European journal of chemistry, 2(3)365-371 (2011).
12) Synthesis of novel Isatin-Thiazoline and Isatin-Benzimidazle conjugates as anti-breast cancer agents.
Azza T. Taher* , Nadia Khalil and Eman Ahmed
Arch Pharm Res. 34(10) 1615-1621 (2011).

13) Novel 1,3,4-heterodiazole analogues: Synthesis and in-vitro antitumor activity.
Azza T. Taher*, Hanan H. Georgey and Hussein I. El-Subbagh
European Journal of Medicinal Chemistry 47 445-451, (2012)

14) Novel pyrimidinone derivatives: Synthesis, antitumor and antimicrobial evaluation.
Azza T. Taher* and Amira A. Helwa
Chem. Bull. Pharm., Japan,. 60(4) 521–530 (2012)

15) Synthesis of Certain 2-Substituted-1H-Benzimidazole Derivatives as Antimicrobial and Cytotoxic agents.
Azza Taher Taher,* Nadia Abdalla Khalil, Eman Mohamed Ahmed, and Yasser Mohamed Ragab
Chem. Bull. Pharm., Japan,. 60(6), 778–784 (2012)

16) Synthesis, Antitumor and Antimicrobial Testing of Some New Thiopyrimidine Analogues
Azza T. Taher* and Amira A. Helwa
Chem. Bull. Pharm., Japan,. 60(10), 1305–1313 (2012)

17) Synthesis and Biological Assessment of Some New Acrylonitrile Derivatives as Potential Antitumor and Antimicrobial Agents.
Azza Taher Taher
Life Science Journal., 9(1), 991-1005 (2012).

18) Synthesis and Bioactivity Evaluation of New 6-Aryl-5-cyano thiouracils as Potential Antimicrobial and Anticancer Agents
Azza Taher Taher, Sahar Mahmoud Abou-Seri.

Molecules, 17, 9868-9886 (2012).

19) Synthesis of new 1,3,4-benzotriazepin-5-one derivatives and their biological evaluation as antitumor agents

Azza Taher Taher, Lamia Wagdy
Arch. Pharm. Res. (Korea), 36:684–693(2013).

20) Synthesis of novel bis-anthraquinone derivatives and their biological evaluation as antitumor agents.
Azza Taher Taher, Gehan Hegazy

Arch Pharm Res.(Korea), 36:573–578 (2013).
21) Synthesis and binding study of certain 6-arylalkanamides As molecular probes for cannabinoid receptor subtypes.

Azza T. Taher*, Hanan H. Kadry, Marco Allarà, Vincenzo Di Marzo, Ashraf H. Abadi, and Khaled A. Abouzid

Journal of Enzyme Inhibition and Medicinal Chemistry, 28(3),436- 439; (2013). DOI: 10.3109/14756366.2011.645241Ltd., UK

22) Synthesis, anti-inflammatory, analgesic and antipyretic activities of novel pyrano[2,3-c]pyrazoles and related fused ring derivatives.
Afaf ElAnsari, Azza Taher Taher, Ahmed Rahmany, and SallyEl-wdan.

Journal of American Science;10(10) 284-294 (2014).

23) Useful four-carbon synthons en route to monastrol analogs
Amr M. Abdou, S. Botros , Rasha A. Hassan, Mona M. Kamel c, Douglass F. Taber , Azza T. Taher.
Tetrahedron, (71) 139-146 (2015).

24) Synthesis and Anti-mycobacterial Evaluation of Some New IsonicotinylHydrazide Analogues.

Maha A. Abdel Hakeem, Azza T. Taher, Suzan Aboel-maaty.
Bulletin of Faculty of Pharmacy, Cairo University 53; 45-52 (2015).

25) Synthesis of novel S-acyl and S-alkylpyrimidinone derivatives as potential cytotoxic agents
Makaram M. Said1 • Azza T. Taher1,2 • Hala B. El-Nassan1

Eman A. El-Kholy1
Res Chem Intermed (2016) 42:6643–666 DOI 10.1007/s11164-016-2487-x
26) Synthesis and cytotoxic activity of certain benzothiazole derivatives against human MCF-7
cancer cell line
Lamia W. Mohamed1 | Azza T. Taher1,2 | Ghada S. Rady3 | Mamdouh M. Ali4 |Abeer E. Mahmoud4

DOI: 10.1111/cbdd.12879
Chem Biol Drug Des.;89 (4) 566–576. (2017).

27) Synthesis and cytotoxic activity of certain trisubstituted azetidin- 2-one derivatives as a cis-restricted combretastatin A-4 analogues
Salwa Elmeligie1 Azza. T. Taher1,2 Nadia A. Khalil1 Ahmed H. El-said

_ The Pharmaceutical Society of Korea 2017
Arch. Pharm. Res.
DOI 10.1007/s12272-016-0849
Arch. Pharm. Res. (2017) 40:13-24

28) Design, synthesis and cytotoxic activity of certain novel chalcone anal- ogous compounds

S. El-Meligie a, Azza T. Taher a, b, Aliaa M. Kamal a, *, A. Youssef c

European Journal of Medicinal Chemistry 126 (2017) 52—60

29) Synthesis and bioactivity evaluation of new pyrimidinone-5-carbonitriles as potential anticancer and antimicrobial agents
Amira A. Helwa1 • Ehab M. Gedawy2 • Sahar M. Abou -Seri3 • Azza T. Taher2,4 •Afaf K. El-Ansary2
Res Chem Intermed , 44 (4), 2685-2702. (2018)

30) Design, synthesis, and biological evaluation of chromeno[2,3-d] pyrimidines as potential cytotoxic agents.

Asmaa.kassab, Nehalelbakhsha., Hala.el-nassan, Azza T. Taher

Future Medicinal Chemistry, 10 (12), 1465-1481(2018)

31) 31)Alkoxyphenylthiazoles with broad-spectrum activity against multi- drug-resistant gram-positive bacterial pathogens

Moustafa ElAwamya, Haroon Mohammadb, Abdelrahman Hussienc, Nader S. Abutalebb, Mohamed Hagrasc,
Rabah A.T. Seryaa, Azza T. Taherd, e, Khaled AM Abouzida, Mohamed N. Sel- eemb, f, ∗∗,Abdelrahman S. Mayhoubc
European Journal of Medicinal Chemistry, 152, 318-328 (2018).

32) Synthesis and biological evaluation of certain new benzimidazole de- rivatives as cytotoxic agents new cytotoxic benzimidazoles
LW Mohamed, AT Taher, GS Rady, MM Ali, AE Mahmoud
Der Pharma Chemica 10 (5), 112-120 (2018).

33) Synthesis, Modeling Studies and Biological Screening of Novel Pyra- zole Derivatives as Potential Analgesic and Anti-inflammatory Agents

AT Taher, MTM Sarg, NRES Ali, NH Elnagdi
Bioorganic chemistry, 103023 (2019).

34) Triazolopyridazine derivatives: Synthesis, Cytotoxic evaluation, c- Met Kinase Activity and Molecular Docking
EM Ahmed, NA Khalil, AT Taher, RH Refaey, YM Nissan
Bioorganic Chemistry, 92, 103272 (2019).

35) Synthesis and in-vitro anti-proliferative evaluation of some pyrazolo[1,5-a]pyrimidines as novel larotrectinib analogs

Mohamed H.AttiaaEman Z.ElrazazbSoad Z.El-EmamcAzza T.TaherdHatem A.Abdel-AzizeKhaled A.M.Abouzidbf
Bioorganic Chemistry 94 ,103458(2020)

36) Evaluation of N-phenyl-2-aminothiazoles for treatment of multi-drug resistant and intracellular Staphylococcus aureus infections
IG Shahin, NS Abutaleb, M Alhashimi, AE Kassab, KO Mohamed, AT. Taher, MN Seleem, AS Mayhoub

European Journal of Medicinal Chemistry 202, 112497(2020)

37) Synthesis and biological evaluation of novel pyrimidine-5-carbonitriles featuring morpholine moiety as antitumor agents
AA Helwa, EM Gedawy, AT Taher, AK ED El-Ansary, SM Abou-Seri

Future Medicinal Chemistry 12 (5), 403-421(2020).
38) Pimenta dioica (L.) Merr. Bioactive Constituents Exert
Anti-SARS-CoV-2 and Anti-Inflammatory Activities:
Molecular Docking and Dynamics, In Vitro, and In Vivo Studies
Heba A. El Gizawy 1,†, Sylvia A. Boshra 2,†, Ahmed Mostafa 3 , Sara H. Mahmoud 3, Muhammad I. Ismail 4 ,
Aisha A. Alsfouk 5 , Azza T. Taher 6,7,* and Ahmed A. Al-Karmalawy
Molecules 2021, 26, 5844. https://doi.org/10.3390/molecules26195844.
39) Newly Synthesized Series of Oxoindole-Oxadiazole Conjugates as Potential Anti-SARS-CoV-2 Agents: In Silico and In Vitro Studies
R El-Masry, AA Al-Karmalawy, RA Alnajjar, S Mahmoud, A Mostafa, Azza T. Taher*
New Journal of Chemistry., 2022, 46, 5078-5090.
DOI: 10.1039/d1nj04816c
URL: https://pubs.rsc.org/en/content/articlehtml/2022/nj/d1nj04816c
40) Comparative Study of the Synthetic Approaches and Biological
Activities of the Bioisosteres of 1,3,4-Oxadiazoles and
1,3,4-Thiadiazoles over the Past Decade
Rana M. El-Masry 1,* , Hanan H. Kadry 2, Azza T. Taher 2,3 and Sahar M. Abou-Seri.
Molecules 2022, 27, 2709.
41) Recent Advances in The Synthesis of Thiazole Ring: Mini Review
IG Shahin, KO Mohamed, A Taher, AS Mayhoub, A Kassab
Bentham Science Publishers 19, 2022

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