| Latest List of Publications |
1. Synthesis of Certain Nitroquinazoline Derivatives structurally related
to some Chemotherapeutic Agents, S. Botros, K.M. Ghoneim and M.
Khalifa*, Egypt. J. Pharm. Sci. 13 , 11-21 (1972).
2. Synthesis of Certain 2- and 3- substituted Derivatives of
6- Nitro-4- Quinazolone, S. Botros, K.M. Ghoneim and M. Khalifa*,
Egypt. J. Pharm. Sci. 16 , 43-48 (1975).
3. Synthesis of some Quinazolone Derivatives Structurally related to
Certain Sedatives and Hypnotics, S. Botros and M. Khalifa*,
Pharmazie, 31, 155 – 157 (1976).
4. Mechanism of Formation of Ethyl Ethylenetetracarboxylate from ethyl
bromomalonate, S. Botros and M. Khalifa*, Egypt. J. Pharm. Sci 16,
57-63 (1975).
5. Synthesis of some 2-Styrylquinazoline Derivatives Structurally Related
to Certain Chemotherapeutic Agents, S. Botros and M. Shaban,
Pharmazie, 33, 646-647 (1978).
6. N-Substituted-1-Aryl-2,4-Dioxo(1H,3H)-3-Quinazolineacetamides,
S. Botros, Pharmazie, 34 , 113-114 (1979).
7. Synthesis of some Quinazoline Compounds related to -Adrenergic
Blocking Agents, S. Botros, Pharmazie, 34 , 746-747 (1979).
8. Synthesis of some Quinazolone Derivatives Structurally Related to
Certain Sedatives, Hypnotics and Anticonvulsant Agents, A.K.El-
Ansary, S. Botros and M. Khalifa*, Pharmazie, 34, 753-754 (1979).
9. Reaction of 2-Ethoxycarbonyl-3,1,4- Benzoxazone with Amines, A.N.
Osman and S. Botros, Pharmazie, 35 , 439 (1980).
10. 5-Styryl-s-triazolo [4,3-c] Quinazolines, M. El-Enany and
S. Botros*, Pharmazie 36 , 62 (1981).
11. Synthesis of Amidrazones from 2-Ethoxycarbonyl-4H-3,1-
Benzoxazin-4- one, A.N. Osman and S. Botros, Pharmazie,
37, 17-18 (1982).
12. Reaction of 2-Ethoxycarbonyl-4H-3,1-Benzoxazin-4-one with
amines,S. Botros and A.N. Osman, Egypt. J.Chem. 25,
579-58(1982).
13. Synthesis of Certain Phthalazine Derivatives of Expected
Pharmacological Activity,E.E Mostafa, S. Botros and B.Abd El-
Fattah*, Egypt. J. Pharm. Sci. 24, 211-223 (1983).
14. Synthesis of Pyrazolo [3,4-b] Pyridine Derivatives, M.A. Shaban,
S. Botros and A.N. Osman, Egypt. J. chem. 27, 709-713 (1984).
15. Zur synthesese Von 1,3,4-oxadiazolyl Und Pyrazolcarbonyl-Indolen,
K.M Ghoneim*, J. Lehman*, B. Abd El Fattah, S. Botros and
A.A. El Gendy, Arch. Pharm. 318, 318-327 (1985).
16. A revisit to the relative importance of KeKule structures on a novel
non Numerical ordering scheme, S. El-Basil*, S. Botros and
M. Esmail, Math. Chem. 17 , 45-74 (1985).
17. Synthesis of Pyrido [2,3-d] Pyrimidines from 2-Amino-3-
cyanopyridines, S. Botros* and F. El-Baih, Egypt . J. chem.
29, 275-281 (1986).
18. Synthesis and Pharmacological Activity of certain Pyrido [2,3-d]
Pyrimidines, F. El-Baih, A.N Osman, S. Botros and M. Khalifa*,
Egypt. J. Pharm. Sci. 27, 323-332(1986).
19. Investigation of the structural requirements for the k-selective opioid
receptor Antagonist, 6B, 6B’ – [Ethylene-bis(oxythyleneimino)]
bis[17-(cyclopropylmethyl)-4,5-epoxymorphinan-3,14-diol] (TENA),
S. Botros, A.W.Lipkowski, A.E.Takemori and P.S. Portoghese*,
J. Med. Chem. 29, 876 (1986).
20. Synthesis of certain Derivatives of 4-Aminoquinazolines, S. Botros*,
M.M. El-Enany, F.M. Amine and L.N. Soliman, Bull. Fac. Pharm,
Cairo Univ. 25, 41-49 (1986).
21. Novel 2-Substituted aminonicotinhydroxamic acids, K.M. Ghoneim,
M.M. Badran, S. Botros and M. Abdel Gawad, J. Egypt. Pharm.Sci.
28 , 9-16 (1987).
22. Synthesis and Biological Evaluation of Zwitterionic opioid Agonists,
S. Botros, A.E. Takemori and P.S. Portoghese*, Egypt. J. Pharm.
Sci. 28, 1-8 (1987).
23. Synthesis of certain Pyridinecarboxamides As Potential
Antihypertensive agents, S. Botros* and M.S. Mohamed, Egypt. J.
Pharm. Sci. 28, 405-411 (1987).
24. Synthesis of 1,4-Disubstituted Piperazines As Potential
antihypertensive Agents , A.N. Osman, S. Botros, Z. Isaac and M.A.
Khayyal, Egypt. J. Pharm. Sci. 29, 131-143 (1988).
25. 1-Substituted-8- Phthalimido-3,6- Dioxaoctanes, Synthesis, Mass
Spectra and reaction with the Opioid Antagonist β –Naltrexamine, S.
Botros and P.S. Portoghese* 20th Conference of Pharmaceutical
Sciences, Feb. 1988.
26. Synthesis of 1,4-Disubstituted Piperazines As Potential
Antihypertensive Agents (part I), K.A.M. Abou-Zeid, K.M. Youssef,
F.M. Amine and S. Botros*, (Chemistry) and Z. Isaac
(Pharmacology), Egypt. J. Pharm. Sci. 30, 429-436 (1989).
27. Synthesis of Novel Disubstituted Piperazines As Potential
Antihypertensive agents, S. Botros *, K.M Youssef (Chemistry) and
Z. Isaac (Pharmacology), Egypt. J. Pharm. Sci. 30, 419-427 (1989).
28. Synthesis, Anti-hypertensive and β- adrenoreceptor antagonist
activities of 3-[4(3-(4-ary1-1-piperaziny1) isopropanoloxy) pheny1]
4(3H) Quinazolones, S. Botros ( Chemistry) and S.F Saad
(Pharmacology), Eur. J. Med. Chem. 24, 585-590 (1989).
29. Synthesis and Antihypertensive Activity of 1,4-Disubstituted
Piperazines, K.A.M. Abou-Zeid, K.M. Youssef, F.M. Amine and S.
Botros*, Egypt. J. Pharm. Sci. 32, 165-174 (1991).
30. Synthesis of 1,4-Disubstituted Piperazines As Potential
Antihypertensive agents, L.N. Soliman, S.M. Roshdy and S. Botros*,
Proceedings of XXI Conference of Pharm. Sci., p 43-51 (1990).
31. Opioid Agonist and Antagonist Activities of Peripherally Selective
Derivatives of Naltrexamine and Oxymorphamine , S. Botros, A.W.
Lipkowsky, D.L. Larson, P.A. Stark, A.E. Takemori and P.S.
Portoghese*, J. Med. Chem. 32, 2068 (1990).
32. Ocular Hypotensive Effect of a series of newly synthesized
Adrenoreceptor blockers, 3-[4-[3-(4- Aryl-1-piperazinyl)
Isopropanoloxy] phenyl] 4(3H) Quinazolones in Rabbits , S.F. Saad,
Nabila M. Kamal, Hassan A. Shabayek and Samir Botros, J. Egypt.
Soc. Pharmacol. & Exptl. Therap. 9 (1), 219-234 (1990).
33. Preliminary study of Cardiac effects of some newly synthesized
β- Adrenoreceptor Blockers, S.F. Saad, S. Botros and Nabila M.
Kamal, Bull.Fac. Pharm. Cairo Univ. 29 , 111-114 (1991).
34. Synthesis and antihypertensive activity of 1,4-disubstituted
piperazines, K.A.M Abou-Zeid, K.M. Youssef, F.M. Amine and S.
Botros*, Egypt. J. Pharm. Sci. 32, 165-174 (1991).
35. Synthesis, Antihypertensive and Adrenoreceptor Antagonist
Activities of 3-[4-[3-(substituted amino)- isopropanoloxy]phenyl]
4(3H) Quinazolones, S.F. Saad, M.M. Ismail and S. Botros, Bull.
Fac. Pharm. Cairo Univ. 30, 175-179 (1992).
36. Synthesis and screening of certain Aminoguanidines as potential
Antihypertensive agents, S. Botros*, A.N Osaman, M.M. Kandeel,
N.A. Khalil and H.A Abd El-Latif, Bull. Fac. Pharm. Cairo Univ.
30, 203-208 (1992).
37. Synthesis and screening of certain Aryloxyacetylaminoguanidines as
potential antihypertensive agents, A.N. Osman, S. Botros*, M.M.
Kandeel, N.A. Khalil and H.A. Abd El-Latif, Indian . J. Chem.
35 B, 446-455 (1996).
38. Synthesis and biological activity of certain pyridobenzodiazepines,
S. Botros*, Adel A. El-Gendy, Mohamed M. Said and A.H.Omar,
Bull. Fac. Pharm. Cairo. Univ. 39, 9-15 (2001).
39. Synthesis of certain (Heterocyclic substituted aryloxy) propanol-
amines as potential adrenoreceptor antagonists, N.A. Khalil,
S. Botros*, L.N. Soliman, F.M. Amin and S. El-Zanfaly, Bull. Fac.
Pharm. Cairo. Univ., 40, No.1, 23-29 (2002).
40. Synthesis of Certain Propanolamines as Potential Adrenoceptor
Antagonists, N.A. Khalil, S. Botros*, L.N. Soliman, F.M. Amin
and S. El-Zanfaly, Bull. Fac. Pharm., Cairo Univ. 40, No.2, 23-29
(2002).
41. Synthesis of Certain substituted Pyridazines and Pyrimido [4,5-c]
Pyridazines of anticipated antimicrobial Activity,
Rasha A. Mohamed, M. Kamel, A. El-Ansary and S. Botros*,
Bull. Fac. Pharm. Cairo. Univ. 43(No3), 35-41 (2005).
42. Synthesis and Antidepressant Activity of Certain Quinoxaline
Derivatives (Part I), M.M. Badran, S. Botros, A. El-Gendy, N.
Abdou, H.R. El-Assi and A. Salem, Bull. Fac. Pharm. Cairo.
Univ. 43,(No3), 57-67 (2005).
43. Novel Quinoxalinobenzodiazepinone and Quinoxalino-
benzoxazepinone Derivatives of Biological interest (Part II),
M.M. Badran, S. Botros, A. El-Gendy, N. Abdou and H.R. El-
Assi, Bull. Fac. Pharm. Cairo.Univ. 43,(No3), 69-72 (2005).
44. Synthesis and antimicrobial activity of certain thiazolopyrimidine
derivatives, S.Botros, L.N. Soliman, Eman M Ahmed and M. Tawfik,
Bull. Fac. Pharm. Cairo Univ., 46 (2), 59-69 (2008).
45. Synthesis and tranquillizing effect of New 1,4- Benzoxazepines,
S.Botros, B.H.Naguib and A.N. Osman, Egypt J. Chem. 54, 565-
578 (2011).
46. Synthesis and tranquilizing effect of new dibenzoxazepines and
Pyridobenzoxazepines, Samir Botros*, Bassem H. Naguib and
Abdelgaber N. Osman, Egypt J. Chem. 54, 691-701 (2011).
47. Phenytoin-based Bivalent Ligands: Design, Synthesis and
anticonvulsant activity, Samir Botros, Nadia A. Khalil, Bassem H.
Naguib, and Yara El-Dash, Arch. Pharm. Res 35, No 12, 2105-
2116 (2012).
48. Synthesis and anticonvulsant activity of new phenytoin derivatives,
S. Botros, Nadia A. Khalil*, Bassem H. Naguib, Yara El-Dash,
European Journal of Medicinal Chemistry . 60, 57-63(2013).
49. Synthesis of Certain Thienopyrimidines of Potential Antitumor
Activity, S. Botros, Omneya M. Khalil, Mona M. Kamel, Yara S. El
Dash, 5th International Scientific Conference of Faculty of
Pharmacy, Cairo University, April 23rd and 24th, 2014.
50. Progress towards the synthesis of Brasilicardin A, Rasha A.
Hassan, Mona M. Kamel, Azza T. Taher and S. Botros, 5th International
Scientific Conference of Faculty of Pharmacy, Cairo University,
April 23rd and 24th, 2014.
51. Useful four-carbon synthons en route to monastrol analogs
Amr M. Abdou , S. Botros , Rasha A. Hassan , Mona M.
Kamel c, Douglass F. Taber , Azza T. Taher, Tetrahedron 71,
139-146 (2015) . |