Professor Dr. / Yassin Mohammed Nissan
Pharmaceutical Chemistry
yassin.nissan@pharma.cu.edu.eg
Latest List of Publications
❖ Synthesis and biological evaluation of new coumarin derivatives as cytotoxic agents
FA Ragab, AAM Eissa, SH Fahim, MA Salem, MA Gamal, YM Nissan
Archiv der Pharmazie, e2100029
❖ Non-ulcerogenic pyrazolyl 2-hydroxychalcones and pyrazolylpyrazolines derived from naturally existing furochromone (khellin): semi-synthesis, docking study and anti-inflammatory activity
FAEF Ragab, YM Nissan, MA Salem, MM Ali, AAMA Selim
Natural Product Research, 1-8
❖ Repurposing of renin inhibitors as SARS-COV-2 main protease inhibitors: A computational study
RH Refaey, MK Al-Ashery, YM Nissan
Virology 554, 48-54, 2021.
❖ Synthesis of Hydroxybenzofuranyl-pyrazolyl and Hydroxyphenyl-pyrazolyl Chalcones and Their Corresponding Pyrazoline Derivatives as COX Inhibitors, Anti-inflammatory and Gastroprotective Agents
FAEF Ragab, EI Mohammed, GAA Jaleel, AAM Abd El-Rahman, YM Nissan
Chemical and Pharmaceutical Bulletin 68 (8), 742-752.
❖ Synthesis and in vitro investigation of novel cytotoxic pyrimidine and pyrazolopyrimidne derivatives showing apoptotic effect
FA Ragab, YM Nissan, EM Seif, A Maher, RK Arafa
Bioorganic Chemistry, 103621, 2020.
❖ New Benzenesulfonamide Scaffold-Based Cytotoxic Agents: Design, Synthesis, cell viability, apoptotic activity and radioactive tracing studies
YM Nissan, KO Mohamed, WA Ahmed, DM Ibrahim, MM Sharaky, ...
Bioorganic Chemistry, 103577, 2020.
❖ Pyrrolo and pyrrolopyrimidine sulfonamides act as cytotoxic agents in hypoxia via inhibition of transmembrane carbonic anhydrases
OM Khalil, AM Kamal, S Bua, HES Teba, YM Nissan, CT Supuran
European Journal of Medicinal Chemistry, 112021, 2020.
❖ Triazolopyridazine derivatives: Synthesis, cytotoxic evaluation, c-Met kinase activity and molecular docking
EM Ahmed, NA Khalil, AT Taher, RH Refaey, YM Nissan
Bioorganic chemistry 92, 103272, 2019.
❖ Neurobehavioral investigation and acetylcholinesterase inhibitory activity study for some new coumarin derivatives
WR Mahmoud, YM Nissan, MM Elsawah, RH Refaey, MF Ragab,KM Amin
European journal of medicinal chemistry 182, 111651, 2019.
❖ New pyrazole derivatives: Synthesis, anti-inflammatory activity, cycloxygenase inhibition assay and evaluation of mPGES
GS Hassan, DEA Rahman, EA Abdelmajeed, RH Refaey, MA Salem, YM Nissan
European Journal of Medicinal Chemistry 171,332-342, 2019
❖ Design and Synthesis of New Quinoxaline Derivatives as Anticancer Agents and Apoptotic Inducers
A El Newahie, YM Nissan, NSM Ismail, A El Ella, A Dalal, SM Khojah, KAM Abouzid
Molecules 24 (6), 1175, 2019.
❖ Synthesis and biological evaluation of some heterocyclic compounds
Mohamed, M.A., Mohamed, Y., Eid, N.M. and Barsoum, F.F.
Journal of Applied Pharmaceutical Research, 6(2), pp.01-15., 2018.
❖ Antimicrobial and anticancer activity of some novel fluorinated thiourea derivatives carrying sulfonamide moieties: synthesis, biological evaluation and molecular docking
MM Ghorab, MS Alsaid, MSA El-Gaby, MM Elaasser, YM Nissan
Chemistry Central Journal 11 (1), 32, 2017
❖ Novel pyrazolopyrimidines: Synthesis, in vitro cytotoxic activity and mechanistic investigation
GS Hassan, DEA Rahman, YM Nissan, EA Abdelmajeed, TM Abdelghany
European Journal of Medicinal Chemistry 138, 565-576, 2017
❖ Design, synthesis and biological evaluation of some novel sulfonamide derivatives as apoptosis inducers
KO Mohamed, YM Nissan, AA El-Malah, WA Ahmed, DM Ibrahim, Tamer M Sakr , Mohamed Motaleb
European Journal of Medicinal Chemistry 135, 424-433, 2017
❖ Novel Sulfonamide Derivatives Carrying a Biologically Active 3, 4-Dimethoxyphenyl Moiety as VEGFR-2 Inhibitors
MM Ghorab, MS Alsaid, YM Nissan, AE Ashour, AA Al-Mishari, A Kumar, SF Ahmed
Chemical and Pharmaceutical Bulletin 64 (12), 1747-1754, 2016
❖ Synthesis and antibacterial activity of novel 2-(arylimino) thiazolidin-4-one and 2-(benzylidenehydrazono)-3-arylthiazolidin-4-one derivatives.
EM El-Hossary, YM Nissan, K Edkins, H Bruhn
Journal of applied pharmaceutical science. 6 (05), 007-017, 2016