|
Master Degree in Pharmaceutical Sciences
General Courses – Faculty Requirements
The candidate studies the compulsory courses as shown in the following table:
Semester |
CodeNo. |
Course Title |
Credit Hours |
Exam. Hours |
Exam. Marks |
Written |
Practical |
Written |
Practical |
First |
2001 |
Computer Science(I). |
[1+1] |
1 |
3 |
50 |
50 |
2002 |
Pharmaceutical Statistics. |
[2+0] |
2 |
-- |
100 |
-- |
Second |
2003 |
Computer Science (II). |
[0+1] |
-- |
3 |
-- |
50 |
2004 |
Scientific Writing. |
[1+0] |
1 |
-- |
50 |
-- |
Total credit hours required |
6 |
|
|
|
|
General Courses – Faculty Requirements
Code No. Credit Hours |
Course Title and Content |
2001 (1+1) |
Computer Science (I):
Computer systems, types of computer
available, A typical microcomputer configuration, computer hardware,
numbers systems, the input devices, the output devices, the storage
devices, computer software, statistical packages, database management
packages, multimedia data management, communication packages, database
digital analysis, computer graph sheets.
Practical Course:-
Computer Basics – MS Windows - MS Word. |
2002 (2) |
Statistics:
Normal and binomial distribution.
Probability, use of factorials, combinations and permutations. Measuring
of central tendency and various distribution modes for pharmaceutical
data. Significance. Testing, sampling procedures and outliers. T-test,
ANOVA, line statistics, correlation and regression. |
2003 (0+1) |
Computer Science (II):
Practical Course:- MS Excel – MS Power
Point - Internet. |
2004 (1) |
Scientific Writing:
Choosing a research problem, using
library, first step in treating data, writing paper, making the paper
interesting, correcting the type written copy, good form and using
tables and illustration, prepublication review, Bibliography, Index. |
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Master Degree in Pharmaceutical Sciences
[Pharmaceutics]
The candidate studies (5) compulsory courses and chooses (1) elective course as shown in the following table:
Semester |
Code No. |
Course Title |
Credits Hour |
Exam. Hours |
Exam. Marks |
First |
2101 |
Physical Pharmacy. |
Compulsory Courses |
[2] |
2 |
100 |
2102 |
Stability of Pharmaceutical Preparations. |
[2] |
2 |
100 |
2103 |
Dosage Form Design. |
[2] |
2 |
100 |
Second |
2104 |
Biopharmaceutics and Applied Pharmacokinetics. |
[2] |
2 |
100 |
2105 |
Advanced Drug Delivery Systems. |
[2] |
2 |
100 |
2106 |
Cosmetics. |
Elective Courses |
[2] |
2 |
100 |
2107 |
Radiopharmaceuticals. |
[2] |
2 |
100 |
2108 |
Drug Targeting. |
[2] |
2 |
100 |
Total credit hours required |
12 |
|
|
Course Content of Master Degree in Pharmaceutical Sciences
[Pharmaceutics]
Code No. Credit Hours |
Course Title and Content |
2101 (2) |
Physical Pharmacy:
States of matter. Thermodynamics. Physical properties of molecules. Solubility and distribution phenomena – complexation and protein binding. Interfacial phenomena. Polymers in pharmacy. Rheology. |
2102 (2) |
Stability of Pharmaceutical Preparations:
Reaction kinetics and drug stability which includes: reaction orders, complex reaction orders: Parallel and consecutive reactions, Dosage forms instability. Routes of degradation Accelerated, stability program. |
2103 (2) |
Dosage Form Design:
Sustained release products: classification, advantages, physicochemical and biological properties of drugs, formulation methods. Microencapsulation. Tablets and capsules, Sterile products. Suppositories. Coarse dispersions. Topical products and aerosols. |
2104 (2) |
Biopharmacokinetics and Applied Pharmacokinetics:
Definitions, factors affecting drug absorption, dissolution: Pharmacopeial and non- Pharmacopeial and biopharmaceutics classification system, Intravenous and oral single dose. Multiple dosing. Compartmental and non compartmental models. Drug clearance. Nonlinear pharmacokinetics. Bioavailability and bioequirence. |
2105 (2) |
Advanced Drug Delivery Systems:
Red blood cells as drug carriers, mucoadhesive drug delivery, transdermal drug delivery and intranasal drug delivery. |
2106 (2) |
Cosmetics:
Technology of cosmetics, Skin products, Dental products, Hair care products, Foot and nail care, Packaging and Pharmaceutical evaluation of cosmetic preparations. |
2107 (2) |
Radiopharmaceuticals:
Radiation types, Radioactive decay and types of decay, Doses of radiation, human protection. Application of radiopharmaceuticals in diagnosis and treatment. |
2108 (2) |
Drug Targeting:
New techniques for drug targeting, Nanotechnology for targeting, Spleen targeting, Cancer cells targeting, Colon targeting, Monoclonal antibodies. |
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Master Degree in Pharmaceutical Sciences
[Industrial Pharmacy]
The candidate studies (5) compulsory courses and chooses (1) elective course as shown in the following table:
Semester |
Code No. |
Course Title |
Credits Hour |
Exam. Hours |
Exam. Marks |
First |
2101 |
Physical Pharmacy. |
Compulsory Courses |
[2] |
2 |
100 |
2102 |
Stability of Pharmaceutical Preparations. |
[2] |
2 |
100 |
2103 |
Dosage Form Design.تصميم الأشكال الصيدلية. |
[2] |
2 |
100 |
Second |
2109 |
GMP, QC, QA & validation, |
[2] |
2 |
100 |
2110 |
Scale up techniques & pilot plant |
[2] |
2 |
100 |
2106 |
Cosmetics. |
Elective Courses |
[2] |
2 |
100 |
2107 |
Radiopharmaceuticals. |
[2] |
2 |
100 |
2111 |
Mechanical Utilities & Services |
[2] |
2 |
100 |
Total credit hours required |
12 |
|
Master Degree in Pharmaceutical Sciences
[Industrial Pharmacy]
Code No.&Credit Hours |
Course Title and Content |
2101 (2) |
Physical Pharmacy
States of matter. Thermodynamics. Physical properties of molecules. Solubility and distribution phenomena
– complexation and protein binding. Interfacial phenomena. Polymers in pharmacy. Rheology. |
2102 (2) |
Stability of Pharmaceutical Preparations
Reaction kinetics and drug stability which includes: reaction orders, complex reaction orders:
Parallel and consecutive reactions, Dosage forms instability. Routes of degradation Accelerated, stability program. |
2103 (2) |
Dosage Form Design
Sustained release products: classification, advantages, physicochemical and biological properties
of drugs, formulation methods. Microencapsulation. Tablets and capsules,
Sterile products. Suppositories. Coarse dispersions. Topical products and aerosols. |
2109 (2) |
GMP, QC, QA & validation
Quality, quality control, quality management, process control, material control, GMP, Personnel,
buildings, equipment, production procedures, packaging and validation.
Basic requirements for pharmaceutical quality management. Total quality
management. Quality costs. Manufacturing quality management. Process
flow charts, process flow analysis, process specification, process validation.
Regulatory aspects, design and performance qualification. Documentation. |
2110 (2) |
Scale up techniques & pilot plant
Problems evolved during transfer the formula from laboratory scale to industrial scale – How
to solve different problems of scaling up- case study. |
2106 (2) |
Cosmetics
Technology of cosmetics, Skin products, Dental products, Hair care products, Foot and nail care,
Packaging and Pharmaceutical evaluation of cosmetic preparations. |
2107 (2) |
Radiopharmaceuticals
Radiation types, Radioactive decay and types of decay, Doses of radiation, human protection. Application
of radiopharmaceuticals in diagnosis and treatment. |
2111 (2) |
Mechanical Utilities & Services
Design of facility utility -mechanical systems-heating-ventilation-air conditioning systems-Fire
protection systems- piping systems- Purified water station-vacuum-Process
gases. |
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Master Degree in Pharmaceutical Sciences
[Pharmacognosy]
The candidate studies (9) compulsory
courses and chooses (1) elective course as shown in the following table:
Semester |
Code No. |
Course Title |
Credits Hour |
Exam. Hours |
Exam. Marks |
First |
2201 |
Plant Cell and Tissue Culture. |
Compulsory Courses |
[1] |
1 |
50 |
2202 |
Isolation and Identification of Natural Products |
[1] |
1 |
50 |
2203 |
Chromatographic Techniques. |
[1] |
1 |
50 |
2204 |
Spectroscopy of Natural Products (NMR, UV, MS and IR). |
[1]< |
1 |
50 |
Second |
2205 |
Biosynthesis in Medicinal Plants. |
[1] |
1 |
50 |
2206 |
Advanced Phytochemistry. |
[1] |
1 |
50 |
2207 |
Advanced Chromatographic Methods. |
[1] |
1 |
50 |
2208 |
Application of Spectroscopy and Structure Elucidation. |
[2] |
2 |
100 |
2209 |
Seminar. |
[1] |
1 |
50 |
2210 |
Herbal Medicine and Aromatherapy. |
Elective Courses |
[2] |
2 |
100 |
2211 |
Marine Natural Products. |
[2] |
2 |
100 |
2212 |
Biotechnology and Genetic Engineering |
[2] |
2 |
100 |
2308 |
Pharmacology of Natural Products. |
[1] |
1 |
50 |
Total credit hours required |
12 |
|
|
Course Content of Master Degree in Pharmaceutical Sciences
[Pharmacognosy]
Code No.& Credit Hours |
Course Title and Content |
2201 (1) |
Plant Cell and Tissue Culture:
The course discuses the facilities and techniques essential for a cell tissue culture laboratory,
with emphasis on culture media, stages of micropropagation, callus-organ-cell
and protoplast culture. |
2202 (1) |
Isolation and Identification of Natural Products:
Candidates are introduced
to the advanced methods for the isolation of natural products belonging
to different chemical classes, as well as to their characterization
and identification. |
2203 (1) |
Chromatographic Techniques:
The course deals with the principles underlying the different chromatographic techniques and
their application in the qualitative and quantitative analysis as well
as in the isolation and purification of natural products. |
2204 (1) |
Spectroscopy of Natural Products (NMR, UV, MS and IR):
The different spectroscopic methods (UV, IR, NMR and MS) are studied as tools for characterizing
natural products and elucidating their structures. |
2205(1) |
Biosynthesis in Medicinal Plants:
Students of this course are introduced to the significance of secondary metabolites in the life
of plants, as well as to methods of studying biosynthesis. Biosynthesis
of examples originating from sugars, acetate, activated isoprene, amino
acids and shikimic acid are studied. |
2206 (1) |
Advanced Phytochemistry:
Recent advances in the chemistry of natural products are presented. Examples of novel structures
discovered in terrestrial plants, bacteria, fungi, lichens and marine
organism and their impact on drug discovery are discussed. |
2207 (1) |
Advanced Chromatographic Methods:
Advanced chromatographic techniques applicable for the qualitative and quantitative analysis
of phytoconstituents as well as for the isolation of pure compounds
are studied. |
2208 (2) |
Application of Spectroscopy and Structure Elucidation:
Application of different spectroscopic methods including UV, IR, NMR and MS in the elucidation
of structure of compounds is studied with examples from different chemical categories. |
2209 (1) |
Seminar:
Seminar of any applicable field of studied topics. |
2210 (2) |
Herbal Medicine and Aromatherapy:
Herbal medicine and aromatherapy considered new approach in complementary medicine so it's
deemed of interest to study their history, new technologies, methodology,
safety and their applications. |
2211 (2) |
Marine Natural Products:
The candidate is introduced to ecology of marine organisms as well as hydrographic and climatic
factors, marine zones and communities and taxonomy. Examples of bioactive
marine organisms are studied chemically and biologically. |
2212 (2) |
Biotechnology and Genetic Engineering:
The course discuses the impact of biotechnology and genetic engineering in the commercial
production of bioactive naturl products as well as in drug discovery
from nature. |
2308 (1) |
Pharmacology of Natural Products:
- Alternative therapies.
- Pharmacology of natural products.
- Vitamins of diet.
- Dietary antioxidants.
- Food – Drug interactions.
- Herb –Drug interactions.
|
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Master Degree in Pharmaceutical Sciences
[Pharmacology and Toxicology]
The candidate studies (5) compulsory courses and chooses (2) elective courses as shown in the following table:
Semester |
Code No. |
Course Title |
Credit Hours |
Exam. Hours |
Exam. Marks |
Written |
Practical |
Written |
Practical |
First |
2301 |
Pharmacometrics. |
Compulsory Courses |
[2+0] |
2 |
-- |
100 |
-- |
2302 |
Toxicometrics. |
[2+0] |
2 |
-- |
100 |
-- |
2303 |
Immuno Pharmacology. |
[2+0] |
2 |
-- |
100 |
-- |
Second |
2304 |
Pathophysiology of Diseases. |
[2+0] |
2 |
-- |
100 |
-- |
2305 |
Experimental Pharmacology. |
[0+2] |
-- |
5 |
-- |
100 |
2306 |
Clinical Pharmacology. |
Elective Courses |
[1+0] |
1 |
-- |
50 |
-- |
2307 |
Drug and Poison Information. |
[1+0] |
1 |
-- |
50 |
-- |
2308 |
Pharmacology of Natural Products. |
[1+0] |
1 |
-- |
50 |
-- |
Total credit hours required |
12 |
|
|
|
|
Course Content of Master Degree in Pharmaceutical Sciences
[Pharmacology and Toxicology]
Code No.&Credit Hours |
Course Title and Content |
2301 (2+0) |
Pharmacometrics:
1- Screening and bioassay of antiulcer drugs, anti – inflammatory drugs….. ets.
2- Detection and evaluation of chemically – incluced liver injury including:
- Hepatic structure and function.
- Classification of chemically induced liver injury.
- Lipid peroxidation.
- Biological antioxidants.
- Hepatotoxic agents.
- Evaluation of hepatic injury.
3- Screening of bioassay of some drugs acting on the central nervous and cardiovascular systems.
|
2302 (2+0) |
Toxicometrics:
1- Qualitative and quantitative assessment of toxicity:
2- Principles and methods of acute and subacute and chronic toxicity:
- Genetic toxicity.
- Methods in testing for carcinogenicity.
- Teratology test methods for laboratory animals.
- Methods in behavioral toxicology.
- Biochemical methods for neuro toxicological analysis.
|
2303 (2+0) |
Immuno Pharmacology:
1 - Introduction to the immune system.
2 - Immunopathology.
3 - Immunostimulation.
4 - Immunosuppression.
|
2304 (2+0) |
Pathophysiology of Diseases:
Etiology and pathophysiology of insomnia, anxiety, psychosomatic diseases, depression, parkinsonism,
all types of epilepsy, pain, rheumatic disease, rheumatic arthritis,
gout, hypertension, angina pectoris, cardiac arrhythmias, atherosclerosis
congestive heart failure brochial asthma, endocrine imbalance.
|
2305 (0+2) |
Experimental Pharmacology:
Practical Course:- Includes hands on application for various techniques in pharmacological
research. |
2306 (1+0) |
Clinical Pharmacology:
Etiology of pathophysiology of cardiovascular central nervous system diseases treatment methodology
with an insight on molecular signaling mechanism. |
2307 (1+0) |
Drug and Poison Information:
1- Drug information center:
- Evidence – Based medicine.
- Drug information services & activities.
- Sources of drug information [1 ry, 2ry, 3ry].
- Systematic approach for answering a drug information request.
- Information technology: Application to drug information [Internet, Medline].
- Evaluation of drug literature [1 ry, 2ry, 3ry literatures].
- Evaluation of clinical studies: Study design and presentation of data.
- Practical application of biostatistics in evaluating clinical studies.
- Types of evaluation & observational studies.
- Drug monograph.
- Careers in drug information.
2- Poison information center:
- Specific approach in poisoned patients.
- Diagnosis of poisoning.
- Managing poison cases.
- Staff precautions in toxicological emergencies.
|
2308 (1+0) |
Pharmacology of Natural Products:
1- Alternative therapies.
2- Pharmacology of natural products.
3- Vitamins of diet.
4- Dietary antioxidants.
5- Food – Drug interactions.
6- Herb –Drug interactions.
|
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Master Degree in Pharmaceutical Sciences
[Microbiology and Immunology]
The candidate studies (6) compulsory courses and chooses (2) elective courses as shown in the following table:
Semester |
Code No. |
Course Title |
Credit Hours< |
Exam. Hours |
Exam. Mark |
First |
2401 |
Advanced Microbiology (I). |
Compulsory Courses |
[2] |
2 |
100 |
2402 |
Immunology (I): Basic Immunology. |
[1] |
1 |
50 |
2403 |
Sterilization and Microbiological Quality Control and Quality Assurance. |
[2] |
2 |
100 |
2404 |
Antimicrobial Agents and Microbial Resistance. |
[2] |
2 |
100 |
Second |
2405 |
Advanced Microbiology (II). |
[1] |
1 |
50 |
2406 |
Immunology (II): Immunologicals and Immunological Applications. |
[2] |
2 |
100 |
2407 |
Advanced Techniques in Microbiological Research. |
Elective Courses |
[1] |
1 |
50 |
2408 |
Strategies for New Antibiotics and Antiviral Agents. |
[1] |
1 |
50 |
2409 |
Biotechnology. |
[1] |
1 |
50 |
2410 |
Special Topics in Microbial Pathogenesis and Emerging Infectious Diseases. |
[1] |
1 |
50 |
Total credit hours required |
12 |
|
|
Course Content of Master Degree in Pharmaceutical Sciences
[Microbiology and Immunology]
Code No. &Credit Hours |
Course Title and Content |
2401 (2) |
Advanced Microbiology (I):
Biochemistry of the
bacterial cell, Metabolism and biosynthetic pathways in microorganisms,
Macromolecules and molecular genetics. |
2402 (1) |
Immunology (I): Basic Immunology:
Components of the immune
system, mechanisms of humoral and cellular immunity, cells and organs
which participate in immunity building, immune system related diseases
and disorders (hypersensitivity, auto immune diseases) ,mechanisms for
tissues and organ rejection.
|
2403 (2) |
Sterilization and Microbiological Quality Control and Quality Assurance:
Aseptic techniques, different methods of sterilization of pharmaceutical preparations, validation
of the sterilization process, methods for reducing the level of contamination
of non-sterile pharmaceutical products, quality control procedures to
assure high level of confidence and standardization of the procedures
used in quality control. |
2404 (2) |
Antimicrobial Agents and Microbial Resistance:
Introduction to antimicrobial
agents, antibiotics and chemotherapeutic agents, nonantibiotics antimicrobial
agents, mode of action, bacterial resistance to antimicrobial agents,
mechanisms of resistance to antimicrobial agents. |
2405 (1) |
Advanced Microbiology (II):
Microbial genetics, gene manipulation, genetic engineering and microbial biotechnology. |
2406 (2) |
Immunology (II): Immunologicals and Immunological Applications:
Molecular immunology, serology in the diagnosis of diseases, therapeutic uses of microbial
toxins [vaccines, toxoids, monoclonal antibodies, etc], quality assurance
of immunologicals. |
2407 (1) |
Advanced Techniques in Microbiological Research:
Recombinant DNA techniques, molecular cloning, PCR techniques and applications of genome bioinformatics. |
2408 (1) |
Strategies for New Antibiotics and Antiviral Agents:
Development of resistance to antibiotics and antiviral agents, Problematic bacteria and viruses,
new classes of antibiotics and antiviral agents and high throughput
systems for screening of new antimicrobial agents. |
2409 (1) |
Biotechnology:
Biotechnology techniques, applications of biotechnology
in food and organic compounds production. |
2410 (1) |
Special Topics in Microbial Pathogenesis and Emerging Infectious Diseases:
Recent infectious diseases outbreaks,host-pathogen relathionship, interaction between infectious
disease and the human immune system, public health measures in these
outbreaks. |
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Master Degree in Pharmaceutical Sciences
[Organic Chemistry]
The candidate studies (6) compulsory courses and chooses (2) elective courses as shown in the following table:
Semester |
Code No. |
Course Title |
Credit Hours |
Exam. Hours |
Exam. Marks |
First |
2501 |
Organic Synthesis. |
Compulsory Courses |
[2] |
2 |
100 |
2502 |
Topics in Organic Reactions. |
[2] |
2 |
100 |
2503 |
Spectral Identificationof Organic Compounds. |
[2] |
2 |
100 |
Second |
2504 |
Medicinal Chemistry. |
[2] |
2 |
100 |
2505 |
Experimental Organic Chemistry. |
[1] |
1 |
50 |
2506 |
Nomenclature of organic Compounds. |
[1] |
1 |
50 |
2507 |
Bioorganic Chemistry. |
Elective Courses |
[1] |
1 |
50 |
2508 |
Pericyclic Chemistry. |
[1] |
1 |
50 |
2509 |
Advanced Heterocyclic Chemistry. |
[1] |
1 |
50 |
2510 |
Synthetic Polymers. |
[1] |
1 |
50 |
2511 |
Relating Structure to Chemical Reactivity. |
[1] |
1 |
50 |
Total credit hours required |
12 |
|
|
Course Content of Master Degree in Pharmaceutical Sciences
[Organic Chemistry]
Code No. & Credit Hours |
Course Title and Content |
2501 (2) |
Organic Synthesis:
A comprehensive course in the synthesis of organic and medicinal compounds using the concept of retrosynthetic
analysis and the disconnection approach.The use of synthones and synthetic
equivalents, functionilization and functional group interconversions
and of protecting groups are illustrated. |
2502 (2) |
Topics in Organic Reactions:
A course in advanced organic chemistry intented for students who have had the
standard undergraduate organic and physical chemistry courses .The organization
is based on reaction types, so the student can be shown that despite
the large number of organic reactions , a relatively few principles
suffice to explain nearly all of them. Accordingly, the course is divided
into the following reactions / mechanisms : Aliphatic Nucleophilic Substitution
, Aromatic Nucleophilic Substitution , Aliphatic Electrophilic
Substitution , Aromatic Electrophilic Substitution , Free Radical
Substitution , Addition to C-C and C-Hetero multiple bonds, Elimination
Reactions, Rearrangements and Oxidations and Reductions. |
2503 (2) |
Spectral Identification of Organic Compounds:
A comprehensive course in the use of UV, Vis, IR, NMR, ESR and mass spectroscopy in the structural identification
and characterization of organic compounds. |
2504 (2) |
Medicinal Chemistry:
An introductory course in medicinal chemistry aimed to graduate
students involved in making and / or studying compounds
of possible biological signifigance. It includes the study of chemical
and stereochemical aspects in drug-receptor interaction, computer- simulated
models for drug-receptor complex, enzyme reactivity from an organic
perspective, major metabolic pathways / activation leading to mutagenicity.
Aspectsconcerning drug selectivity and discussion of selected recent
articles in the field are also included. |
2505 (1) |
Experimental Organic Chemistry:
This course illustrates safety procedures and experimental
techniques used in the synthesis, isolation, purification and identification
of organic compounds. It is intented for graduate students starting
their experimental research in organic chemistry. |
2506 (1) |
Nomenclature of Organic Compound:
This course involves the application of the most updated IUPAC rules and other methods for the nomenclature
of acyclic, Monocyclic, Fused polycyclic, Bridged and Spiro hydrocarbons
and hetero systems. |
2507 (1) |
ABioorganic Chemistry:
Carbohydrates: Structure,stereochemistry, conformational analysis,
chemical reactions and structure determination of carbohydrates
Proteins: Classification, stereochemistry, synthesis, chemical and some biochemical
reactions of amino acids / secondry and tertiary structure of peptides
/ protein quaternary structure. Lipids: Structure, stereochemistry, biosynthesis
of fatty acids. phospholipids, prostaglandins, terpenes , steroids and
carotenoids. |
2508 (1) |
APericyclic Chemistry:
Study of concerted reactions which obey principles of conservation
of orbital symmetry . The course studies three types of pericyclic reactions;
Electrocyclic Reactions, Cycloaddition Reactions and Sigmatropic Rearrangements.
Modes of transition state structures leading to different stereochemical
outcome are discussed. A brief introduction in Huckel MO theory
is presented at the beginning of this course to familiarize
the student with the subject. |
2509 (1) |
Advanced Heterocyclic Chemistry:
The aim of this course is to present a unified account of fundamental heterocyclic chemistry on an advanced
level in order to give better and broader understanding of this important
part of chemistry. Emphasis is placed on the correlation between the
chemical reactivity of various heterocyclic ring systems. Synthesis
of heterocyclic compounds using the disconnection approach
and the biological significance of some heterocyclic systems are included. |
2510(1) |
Synthetic Polymers:
A general course in synthetic polymer with emphasis on relating
structure to physical properties. It includes classification of polymers
according to reaction type, macromolecular growth, structure and properties.
A specific part on synthetic polymers that mimic natural polymers is
included. |
2511 (1) |
Relating structure to chemical reactivity:
A specific course on relating noncovalent interactions to reactivity, regio- and stereoselectivity of a reaction.
Subjects such as steric effect, Neighbouring group participation, solvent
effect and complex formation are discussed with illustrative examples. |
To Top
Master Degree in Pharmaceutical Sciences
[Pharmaceutical Analytical Chemistry]
The candidate studies (6) compulsory courses and chooses (2) elective courses as shown in the following table:
Semester |
Code No. |
Course Title |
>Credit Hours |
Exam. Hours |
Exam. Marks |
First |
2601 |
Advanced Methods of Instrumental Analysis. |
Compulsory Courses |
[2] |
2 |
100 |
2602 |
Quality Control in Pharmaceutical Industry. |
[2] |
2 |
100 |
2603 |
Biomathematics (I). |
[1] |
1 |
50 |
Second |
2604 |
Separation Analysis Techniques. |
[2] |
2 |
100 |
2605 |
Stability Indicating Methods of Analysis.< |
[2] |
2 |
100 |
2606 |
Biomathematics (II). |
[1] |
1 |
50 |
2607 |
Functional Groups Analysis. |
Elective Courses |
[1] |
1 |
50 |
2608 |
Thermal Analysis. |
[1] |
1 |
50 |
2609 |
Environmental Analysis. |
[1] |
1 |
50 |
Total credit hours required |
12 |
|
|
Course Content of Master Degree in Pharmaceutical Sciences
[Pharmaceutical Analytical Chemistry]
Code No. & Credit Hours |
Course Title and Content |
2601 (2) |
Advanced Methods of Instrumental Analysis:
This course includes the study of molecular absorption and emission, visible – ultraviolet, infrared, atomic absorption
and emission, nuclear magnetic resonance principles, instruments, recent
trends and analytical applications of these methods and electrochemical
methods of analysis. |
2602 (2) |
Quality Control in Pharmaceutical Industry:
This course includes total quality management, reference standard, development, optimization and validation of analytical
methods and good analytical practice [GAP] and good laboratory practice [GLP]. |
2603 (1) |
Biomathematics (I):
Determination of matrices – numerical integrations – curve filling approximation. |
2604 (2) |
Separation Analysis Techniques:
This course includes different chromatographic methods of analysis; gas chromatography high performance liquid chromatography
and electrophoresis especially principles – instruments and applications. |
2605 (2) |
Stability Indicating Methods of Analysis:
This course includes selective determination of intact drug in the presence of its degradation
products based on extraction techniques chromatographic and spectroscopic
techniques. |
2606(1) |
Biomathematics (II):
Energy level and molecular orbitals spectrophotometric
analysis pharmacokinetics [dilution problems]. |
2607(1) |
Functional Groups Analysis:
This course includes direct and indirect determination of pharmaceutical compounds through preliminary reactions
based on their function groups. |
2608 (1) |
Thermal Analysis:
Study of thermal techniques: Thermo gravity, derivative thermo gravity, differential thermal analysis, differential
scanning calometry, heating and cooling curves, dilatometry, evolved
gas deterction and analysis, .. etc, definitions, instruments, factors
affecting curves and application. |
2609 (1) |
Environmental Analysis:
Air pollution: Air pollutants, sampling, monitoring and methods of analysis [Sox, Nox,
Co, Pm, soots, metal ions].
Water pollution: Water pollutants, water quality parameters [TDS, TSS, DO, BOD, COD,
PH, temp., sediments, hardness, metal ions, oil grease, anions, …… etc]
soil analysis. |
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Master Degree in Pharmaceutical Sciences
[Biochemistry Chemistry]
The candidate studies (6) compulsory courses and chooses (2) elective courses as shown in the following table:
Semester |
Code No. |
Course Title |
Credits Hour |
Exam. Hours |
Exam. Marks |
First |
2701 |
Biochemistry (I). |
Compulsory Courses |
[3] |
3 |
150 |
2702 |
Biochemistry Laboratory Techniques. |
[1] |
1 |
50 |
Second |
2703 |
Biochemistry (II). |
[3] |
3 |
150 |
2704 |
Molecular Biology. |
[2] |
2 |
100 |
2507 |
Bioorganic Chemistry. |
[1] |
1 |
50 |
2705 |
Interaction of Nutrients and Drugs on Biochemical Laboratory Data. |
Elective Courses |
[1] |
1 |
50 |
2706 |
Nutrition in Disease Prevention and Cure. |
[1] |
1 |
50 |
2707 |
Seminar. |
[1] |
-- |
50 |
Total credit hours required |
12 |
|
|
Course Content of Master Degree in Pharmaceutical Sciences
[Biochemistry]
Code No.&Credit Hours |
Course Title and Content |
2701 (3) |
Biochemistry (I):
- Chemistry of biomolecules and how this relates to cell structure.
- Biomembranes: the structure and function of biological membranes with emphasis on membrane protein.
- Proteins and proteomics: protein structure and chemistry include structural motifs; ligand binding, conformational
changes, chemical modification; protein folding, structure prediction
by molecular modeling, post- translational modifications; protein-protein interaction and metalloproteins..
- Enzymology: The structure, mechanism and biological interactions of enzymes with regard to chemical principles of kinetics and reaction.
- Micronutrients: Vitamins and minerals. |
2702 (1) |
Biochemistry Laboratory Techniques:
Modern biochemical techniques for analysis of different biochemical molecules.
Laboratory safety, centrifugation, data analysis, use of radioisotopes, bioinformatics and a selection of protein
characterization techniques, chromatography, gel electrophoresis, ELISA
techniques and mass spectrometry. |
2703 (3) |
Biochemistry (II):
- Energy metabolism.
- Regulation of metabolism and signal transduction the structure, function, compartmentation of selected metabolic pathways in microbes, plants and animals (carbohydrate metabolism, lipid and steroidogenesis (biosynthesis) and nitrogen metabolism.
- Signal transduction pathways from the membrane to nucleus and structure and function of protein kinases and protein phosphatases.
- Hormones: actions and their metabolic roles.
- Metabolism of individual tissues.
- Cellular mechanisms of metabolic diseases. |
2704 (2) |
Molecular Biology:
Chemical structure and physical characterization of nucleic acids, DNA toplogy, the synthesis
of nucleotides, DNA,RNA and proteins. Nucleic acid-protein interaction
as related to transcription and chromosome structure.
Control mechanisms of transcription and gene expression.
Molecular biology techniques (Recombinant DNA and cloning of DNA molecules and their applications. |
2507 (1) |
Bioorganic Chemistry:
Carbohydrates: Structure ,stereochemistry, conformational analysis,
chemical reactions and structure determination of carbohydrates
Proteins: Classification, stereochemistry, synthesis, chemical and some biochemical
reactions of amino acids / secondry and tertiary structure of peptides / protein quaternary structure.
Lipids: Structure, stereochemistry, biosynthesis of fatty acids. phospholipids, prostaglandins, terpenes , steroids and
carotenoids. |
2705 (1) |
Interaction of Nutrients and Drugs on Biochemical Laboratory Data:
|
2706 (1) |
Nutrition in Disease Prevention and Cure:
|
2707 (1) |
Seminar:
Special topics of interest presented by students with free discussion. |
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Master Degree in Pharmaceutical Sciences
[Pharmaceutical Chemistry]
The candidate studies (6) compulsory courses and chooses (1) elective course as shown in the following table:
Semester |
Code No. |
Course Title |
Credit Hours |
Exam. Hours |
Exam. Marks |
First |
2801 |
Drug Design (I). |
Compulsory Courses |
[2] |
2 |
100 |
2802 |
Spectroscopic and Chromatographic Studies in Pharmaceutical Chemistry (I). |
[2] |
2 |
100 |
2803 |
Advances Synthesis of Drugs. |
[2] |
2 |
100 |
Second |
2804 |
Drug Design (II). |
[1] |
1 |
50 |
2805 |
Spectroscopic and Chromatographic Studies in Pharmaceutical Chemistry (II). |
[1] |
1 |
50 |
2806 |
Advanced Topics in Pharmaceutical Medicinal Chemistry. |
[2] |
2 |
100 |
2807 |
Toxicological Chemistry. |
Elective Courses |
[2] |
2 |
100 |
2808 |
Biopharmaceutical Reaction Mechanisms. |
[2] |
2 |
100 |
2809 |
Modern Techniques in Pharmaceutical Analysis. |
[2] |
2 |
100 |
Total credit hours required |
12 |
|
|
Course Content of Master Degree in Pharmaceutical Sciences
[Pharmaceutical Chemistry]
Code No.&Credit Hours |
Course Title and Content |
2801 (2) |
Drug Design (I):
Quantitative approaches to structure activity relationship, molecular modeling and computer aided drug design,
protein crystallography and drug discovery, combinatorial chemistry,
structure activity relationship by NMR and MS. |
2802 (2) |
Spectroscopic and Chromatographic Studies in Pharmaceutical Chemistry (I):
The course involves the utility of spectroscopy and chromatography for the elucidation of
chemical structure, separation and quantitation of drugs. Spectroscopy
comprises UV-visible, infrared, and mean, infrared absorption, also Raman scattering. are also included. |
2803 (2) |
Advances Synthesis of Drugs:
Study of new synthetic methods for the prepration of certain examples of drugs belonging to
different medicinal classes as: Antibacterial, anti-inflammatory selective
cyclogenase-II inhibitors, non sedating antihistaminic, antidepressant,
Antiasthmatic, triptans for migrane, atorvastatin calcium, Antithrombotics.
The synthetic methods includes: Microwave synthesis, biotechnological
methods and combinational chemistry, …. etc. |
2804 (1) |
Drug Design (II):
The design of peptidomimetics and enzyme inhibitors, the design of prodrug and bioprecursors, macromolecular
carriers for drug targeting, the chemical and physicochemical solution
to formulation problems. |
2805 (1) |
Spectroscopic and Chromatographic Studies in Pharmaceutical Chemistry (II):
The course involves the utility of spectroscopy and chromatography for the elucidation of chemical structure, separation and quantitation of drugs.
Fluorimetry, 1 HNMR, 13 CNMR and mass spectrometry are also included. |
2806 (2) |
Advanced Topics in Pharmaceutical Medicinal Chemistry:
This course will be designed by selecting advanced topics in pharmaceutical medicinal chemistry
for example alteration of drug metabolism through structural modifications.
Modernization in the design of synthetic pathways of drugs, solid phase as a useful method in drug synthesis, …….etc. |
2807 (2) |
Toxicological Chemistry:
Selective toxicity study, Comparative distribution, biochemistry, cytology, stereochemistry,
Selective toxicity examples; Cancer chemotherapy, antibiotics, sulfonamides,
anti-tubercular….etc. |
2808 (2) |
Biopharmaceutical Reaction Mechanisms:
The aim of this course is to relate chemical phenomena with biological activity. It includes:
the study of chemical aspects in drug, receptor interaction, major metabolic
pathways and activation of the drugs [with illustrative examples]. Coenzyme
catalysis and some biochemical reactions of amino acids, with discussion
of selected recent articles in the field , competitive, non-competitive,
and uncompetitive and other types of enzyme inactivators with illustrative
examples. |
2809 (2) |
Modern Techniques in Pharmaceutical Analysis:
The course includes modern techniques such as electrophoresis, near-infrared absorption,
high performance liquid chromatography in the analysis of drugs in their
either as single compartment (Pharmaceutical formulation) or in combination
with other drug. The course aims to study in the presence of exepients,
degradates or metabolites |
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Master Degree in Pharmaceutical Sciences
[Clinical Pharmacy]
The candidate studies (4) compulsory courses and chooses (1) elective course as shown in the following table:
Semester |
Code No. |
Course Title |
Credits Hour |
Exam. Hours |
Exam. Marks |
First |
2901 |
Pharmacotherapeutics (I). |
Compulsory Courses |
[3] |
3 |
150 |
2902 |
Clinical Pharmacokinetics. |
[4] |
3 |
200 |
Second |
2903 |
Pharmacotherapeutics (II). |
[3] |
3 |
150 |
2904 |
Pharmaceutical Care. |
[2] |
2 |
100 |
2905 |
Pharmacy Practice. |
Elective Courses |
[2] |
2 |
100 |
2906 |
Bases of Therapeutic Literature Evaluation and Biostatistics. |
[2] |
2 |
100 |
Total credit hours required |
14 |
|
|
Course Content of Master Degree in Pharmaceutical Sciences
[Clinical Pharmacy]
Code No.&Credit Hours |
Course Title and Content |
2901 (3) |
Pharmacotherapeutics (I):
Introduces different antibiotics, antifungal and antiviral therapy. Case discussion incorporated for various disease
states, with emphasis on drug interactions, adverse drug reactions,
dosing monitoring and patient counseling. It also provides fundamental
understanding of gastrointestinal tract and pathophysiology of different
diseases. Topics include conditions such as peptic ulcer, irritable
bowel syndrome, gastrointestinal reflux disease and drug induce peptic
ulcers will be discussed through the course with emphasis on therapeutic
option and significant drug interaction and patient counseling. Diseases
of upper and lower respiratory system will be also discussed and studied
in this class the class will discuss the cases of cardiology 1: ke hypertension
angina. |
2902 (4) |
Clinical Pharmacokinetics:
The class will deal with introduction to advanced concepts in clinical pharmacokinetics
with emphasis on special patient populations and specific drugs. Drug
dosing to renal impaired patients and patients with live problems will
be of interest. Mechanisms and kinetics of drug clearance through liver
enzymes and cytochrom P450 system will be discussed. |
2903 (3) |
Pharmacotherapeutics (II):
Topics include conditions such as diabetes mellitus; hyperthyroidism and hypothyroidism will be
discussed in details with emphasis on therapeutic choices, drug interactions,
therapeutic monitoring and patient counseling. The class will also provide
an understanding of basic principles of oncology. Topics such as breast
cancer, leukemia and liver cancer will be discussed with emphasis on
therapeutic choices, side effects, therapeutic monitoring, drug interaction
and patient counseling. Nutritional support and psychological state
of the cancer patients will be also introduced in brief. Nephrology
and kidney diseases will be also of interest in this class. Cases such
as acute and chronic glomerulonephritis, urinary tract infections, drug
induced renal disorders, acute and chronic renal failure and drug dosing
in renally impaired patients will be discussed and studied in this class. |
2904 (2) |
Pharmaceutical Care:
This course introduces students to the philosophy of practice, professionalism, patient adherence, patient counseling,
patient oriented pharmaceutical care, patient interview, review of medical
records, assessment of compliance, drug therapy assessment skills, and
monitoring and modifying the pharmaceutical care plan with the goal
of assuring the improvement of patient quality of life. |
2905 (2) |
Pharmacy Practice:
Pharmacy practice I provides fundamental understanding of functions, responsibities, and
outcomes of pharmacy practice in modern health care system. Introducing
fundamental concepts of pharmaceutical care and patient counseling with
emphasis on communication skills, patient interview and medical history
documentation. The course will also give special interest for
special patient groups [geriatric, pediatric, ….. etc] The course
also introduces the basic techniques of physical assessment. Student
will apply their medical information on several patient eases and therapeutic
plans through problem based learning technique. |
2906 (2) |
Bases of Therapeutic Literature Evaluation and Biostatistics:
Provides the basic information about literature criticism and how to evaluate information
through certain scientific criteria. Basic biostatistics with regard
to clinical trials using case study analysis. Introducing experimental
design for clinical studies and methods of analysis in each design. |
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